Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   I6H73_RS01370 Genome accession   NZ_CP066073
Coordinates   263477..264238 (+) Length   253 a.a.
NCBI ID   WP_003054827.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1016     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 258477..269238
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H73_RS01355 (I6H73_01355) - 258766..260334 (-) 1569 WP_003054832.1 ABC transporter substrate-binding protein/permease -
  I6H73_RS01360 (I6H73_01360) - 260533..262428 (+) 1896 Protein_264 DUF2207 domain-containing protein -
  I6H73_RS01365 (I6H73_01365) - 262494..263333 (+) 840 WP_012766572.1 undecaprenyl-diphosphate phosphatase -
  I6H73_RS01370 (I6H73_01370) mecA 263477..264238 (+) 762 WP_003054827.1 adaptor protein MecA Regulator
  I6H73_RS01375 (I6H73_01375) - 264245..265414 (+) 1170 WP_003054822.1 MraY family glycosyltransferase -
  I6H73_RS01380 (I6H73_01380) sufC 265527..266297 (+) 771 WP_003054885.1 Fe-S cluster assembly ATPase SufC -
  I6H73_RS01385 (I6H73_01385) sufD 266393..267655 (+) 1263 WP_003054871.1 Fe-S cluster assembly protein SufD -
  I6H73_RS01390 (I6H73_01390) - 267686..268912 (+) 1227 WP_003054824.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29057.69 Da        Isoelectric Point: 4.0755

>NTDB_id=517160 I6H73_RS01370 WP_003054827.1 263477..264238(+) (mecA) [Streptococcus dysgalactiae strain FDAARGOS_1016]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKDLNLEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEMMEDVVEATLASQTEETAEEVGQEPELLDYVH
YVLDFATLSEAVAFSQTIDFPVEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEHASPGTKTRGYLQEHGVQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=517160 I6H73_RS01370 WP_003054827.1 263477..264238(+) (mecA) [Streptococcus dysgalactiae strain FDAARGOS_1016]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGGATGGAATT
AAAAGATTTCCTCATTCCTCAAGAAAAAACGGAAGAGTTCTTCTACTCTGTCATGGATGAGTTGGACCTACCAGACAATT
TCAAAGATAGTGGCATGCTTAGCTTTCGTGTGACCCCTAGAAAAGACCGTTTGGATGTCTTTGTAACCAAGTCTGAACTC
AATAAGGACCTTAATCTTGAAGATTTAGCTGACTTGGGAGATATCTCTCAAATGACTCCTGAAGACTTTTTCAAGAGCTT
GGAACAATCTATGCGAGAAAAAGGGGATGTTAATGCCCATGAGAAACTGGAAAAAATTGAAGAAATGATGGAAGATGTTG
TCGAAGCCACTCTAGCTAGTCAAACGGAAGAGACCGCTGAGGAAGTGGGTCAAGAACCAGAGCTGTTAGATTACGTGCAT
TATGTTTTGGACTTTGCAACACTTTCAGAGGCCGTCGCTTTTTCTCAGACAATTGATTTTCCTGTTGAAGCTTCAGAATT
GTACAAAGGTGACAGCCGTTATCATATGACGATTTTATTAGATGTTCAGCAGCAACCATCTTATTTTGCCAATGTGATGT
ATGCAAGACTGATTGAGCATGCTAGTCCTGGAACAAAAACCAGAGGTTACTTACAAGAGCATGGCGTACAATTGATTTTG
GATGGGGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.4

98.814

0.636
  mecA Streptococcus thermophilus LMD-9

57.43

98.419

0.565
  mecA Streptococcus thermophilus LMG 18311

56.627

98.419

0.557
  mecA Streptococcus pneumoniae Rx1

47.843

100

0.482
  mecA Streptococcus pneumoniae D39

47.843

100

0.482
  mecA Streptococcus pneumoniae R6

47.843

100

0.482
  mecA Streptococcus pneumoniae TIGR4

47.843

100

0.482