Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   I6H74_RS10740 Genome accession   NZ_CP066069
Coordinates   2163173..2163934 (-) Length   253 a.a.
NCBI ID   WP_003059809.1    Uniprot ID   A0A9X5LVZ2
Organism   Streptococcus dysgalactiae strain FDAARGOS_1017     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2158173..2168934
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H74_RS10720 (I6H74_10715) - 2158499..2159725 (-) 1227 WP_003062308.1 cysteine desulfurase -
  I6H74_RS10725 (I6H74_10720) sufD 2159756..2161018 (-) 1263 WP_048327757.1 Fe-S cluster assembly protein SufD -
  I6H74_RS10730 (I6H74_10725) sufC 2161114..2161884 (-) 771 WP_003061584.1 Fe-S cluster assembly ATPase SufC -
  I6H74_RS10735 (I6H74_10730) - 2161997..2163166 (-) 1170 WP_003054822.1 MraY family glycosyltransferase -
  I6H74_RS10740 (I6H74_10735) mecA 2163173..2163934 (-) 762 WP_003059809.1 adaptor protein MecA Regulator
  I6H74_RS10745 (I6H74_10740) - 2164078..2164917 (-) 840 WP_115256751.1 undecaprenyl-diphosphate phosphatase -
  I6H74_RS10750 (I6H74_10745) - 2164984..2166909 (-) 1926 WP_115256750.1 DUF2207 domain-containing protein -
  I6H74_RS10755 (I6H74_10750) - 2167108..2168676 (+) 1569 WP_115256749.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29071.72 Da        Isoelectric Point: 4.0755

>NTDB_id=517131 I6H74_RS10740 WP_003059809.1 2163173..2163934(-) (mecA) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKDLNLEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEMMEDVVEATLASQTEETAEEVGQEPELLDYVH
YVLDFATLSEAVAFSQTIDFPVEASELYKGDSRYHMTILLDVQQQPSYFANVMYARLIEHASPGTKTRAYLQEHGVQLIL
DGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=517131 I6H74_RS10740 WP_003059809.1 2163173..2163934(-) (mecA) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGGATGGAATT
AAAAGATTTCCTCATTCCTCAAGAAAAAACGGAAGAGTTCTTCTACTCTGTCATGGATGAGTTGGACCTACCAGACAATT
TCAAAGATAGTGGCATGCTTAGCTTTCGTGTGACCCCTAGAAAAGACCGTTTGGATGTCTTTGTAACCAAGTCTGAACTC
AATAAGGACCTTAATCTTGAAGATTTAGCTGACTTGGGAGATATCTCTCAAATGACTCCTGAAGACTTTTTCAAGAGCTT
GGAACAATCTATGCGAGAAAAAGGGGATGTTAATGCTCATGAGAAACTGGAAAAAATTGAAGAAATGATGGAAGATGTTG
TCGAAGCCACTCTAGCTAGTCAAACGGAAGAGACCGCTGAGGAAGTGGGTCAAGAACCAGAGCTGTTAGATTACGTGCAT
TATGTTTTGGACTTTGCAACACTTTCAGAGGCCGTCGCTTTTTCTCAGACAATTGATTTTCCTGTTGAAGCTTCAGAATT
GTACAAAGGTGACAGCCGTTATCATATGACGATTTTATTAGATGTTCAGCAGCAACCATCTTATTTTGCCAATGTGATGT
ATGCAAGACTGATTGAGCATGCTAGTCCTGGAACAAAAACCAGAGCTTACTTACAAGAGCATGGCGTACAATTGATTTTG
GATGGGGCTGTTGAGCAATTACGAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

64.8

98.814

0.64
  mecA Streptococcus thermophilus LMD-9

57.43

98.419

0.565
  mecA Streptococcus thermophilus LMG 18311

56.627

98.419

0.557
  mecA Streptococcus pneumoniae Rx1

47.843

100

0.482
  mecA Streptococcus pneumoniae D39

47.843

100

0.482
  mecA Streptococcus pneumoniae R6

47.843

100

0.482
  mecA Streptococcus pneumoniae TIGR4

47.843

100

0.482