Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   I6H78_RS09000 Genome accession   NZ_CP066059
Coordinates   1842110..1842850 (+) Length   246 a.a.
NCBI ID   WP_000782704.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1837110..1847850
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS08990 (I6H78_08990) - 1837950..1840463 (+) 2514 WP_198459471.1 MBL fold metallo-hydrolase -
  I6H78_RS08995 (I6H78_08995) - 1840509..1841987 (-) 1479 WP_061413759.1 oligosaccharide flippase family protein -
  I6H78_RS09000 (I6H78_09000) mecA 1842110..1842850 (+) 741 WP_000782704.1 adaptor protein MecA Regulator
  I6H78_RS09005 (I6H78_09005) - 1842998..1844284 (+) 1287 WP_198459472.1 homoserine dehydrogenase -
  I6H78_RS09010 (I6H78_09010) thrB 1844286..1845155 (+) 870 WP_198459473.1 homoserine kinase -
  I6H78_RS09015 (I6H78_09015) msrB 1845369..1846307 (+) 939 WP_198459474.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28497.30 Da        Isoelectric Point: 4.1097

>NTDB_id=516996 I6H78_RS09000 WP_000782704.1 1842110..1842850(+) (mecA) [Streptococcus oralis strain FDAARGOS_1021]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAQMSPDEFLKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQADKETESKKEPYIYYILRFA
SLADLVAFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVLG
LQKIRS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=516996 I6H78_RS09000 WP_000782704.1 1842110..1842850(+) (mecA) [Streptococcus oralis strain FDAARGOS_1021]
ATGAAGATGAAACAAATTAGTGATACAACACTGAAAATCACGATGACTTTAGATGATTTGATGGATCGGGGAATGGAGAT
TGCAGACTTTCTCGTCCCTCAGGAGAAAACCGAAGAGTTTTTCTATGCTATTTTAGATGAGTTAGAGATGCCAGACAATT
TCTTGGATAGTGGCATGCTGAGTTTCCGCGTGACGCCAAAACCTGATAAGGTGGACGTCTTTGTGACCAAATCCAAGATT
GACCAAAATCTGGATTTTGAAGATTTGGCGGATCTACCAGACATGGAAGAATTAGCCCAAATGTCGCCGGATGAATTTCT
CAAAACCTTGGAAAAGAGCATTGCAGATAAGACCAAGGACGATATTGAGGCCATCCAATCTCTAGAGCAGGTCGAAGCAA
AGGAAGAAGAGCAAGAGCAGGCAGACAAGGAGACTGAGAGTAAGAAAGAACCTTATATATACTATATCCTGCGCTTTGCA
AGCCTTGCTGACTTGGTTGCTTTTGCAAAGACGGTTAACTACCAGATGGAAACATCTGAACTCTATAAGATGAATGGGCA
CTACTATTTGACAATCTTAGTCGATGTGGAAAATCATCCAAGTCCATATCCGGCTTGGCTCTTGGCTCGTATGCGTGAGT
TTGCAGACGACAGTGACATCAGCCGTTCAGTCTTGCAAGAGTATGGGCAAATATTGATTAACCATGACGCAGTTCTCGGC
CTGCAAAAGATTCGCTCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

90.984

99.187

0.902
  mecA Streptococcus pneumoniae D39

90.984

99.187

0.902
  mecA Streptococcus pneumoniae R6

90.984

99.187

0.902
  mecA Streptococcus pneumoniae TIGR4

90.574

99.187

0.898
  mecA Streptococcus thermophilus LMD-9

47.222

100

0.484
  mecA Streptococcus mutans UA159

48.361

99.187

0.48
  mecA Streptococcus thermophilus LMG 18311

46.825

100

0.48