Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   I6H78_RS05535 Genome accession   NZ_CP066059
Coordinates   1136946..1137608 (+) Length   220 a.a.
NCBI ID   WP_198459047.1    Uniprot ID   A0A7T4IRA7
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 1138433..1138897 1136946..1137608 flank 825


Gene organization within MGE regions


Location: 1136946..1138897
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS05535 (I6H78_05535) comFC/cflB 1136946..1137608 (+) 663 WP_198459047.1 ComF family protein Machinery gene
  I6H78_RS05540 (I6H78_05540) hpf 1137688..1138236 (+) 549 WP_198459048.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  I6H78_RS05545 (I6H78_05545) tnpA 1138433..1138897 (+) 465 WP_198459049.1 IS200/IS605 family transposase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24881.93 Da        Isoelectric Point: 8.1486

>NTDB_id=516973 I6H78_RS05535 WP_198459047.1 1136946..1137608(+) (comFC/cflB) [Streptococcus oralis strain FDAARGOS_1021]
MNCLLCGQTTKGELTFSSLFLLKDDCSYLCSDCASSFEKIGENYCPNCMKTGMSTKCQDCKLWCKEGVWVDHKAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFAPVLAEELKKYKGYQFVVIPLSPGRLLERGFNQVEGLVEAAGFSFKDILGKREESASSS
KSRLERLATEIPFFIKDGISLPKKILLIDDIYTTGATVNRVKRLLEEAGALEVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=516973 I6H78_RS05535 WP_198459047.1 1136946..1137608(+) (comFC/cflB) [Streptococcus oralis strain FDAARGOS_1021]
ATGAATTGTTTACTATGTGGCCAGACTACAAAGGGTGAGCTTACTTTTAGTAGTCTCTTCCTTTTGAAGGATGACTGCAG
TTATCTTTGTTCAGATTGTGCTTCTAGTTTTGAGAAGATTGGTGAGAATTATTGCCCAAACTGTATGAAAACAGGCATGT
CAACTAAGTGTCAAGATTGTAAACTTTGGTGTAAAGAAGGAGTTTGGGTTGATCATAAGGCAATCTTTACCTATAATCAA
GCTATGAAAGACTTTTTCAGTCGCTATAAGTTTGATGGCGATTTTTTGCTTAGAAAAGTTTTTGCTCCTGTTCTTGCTGA
GGAGCTGAAAAAGTATAAAGGTTATCAATTTGTTGTAATTCCCCTAAGTCCTGGAAGATTGCTTGAGAGGGGGTTCAACC
AAGTCGAGGGTTTGGTTGAGGCAGCAGGCTTTTCTTTTAAAGATATATTAGGAAAAAGAGAAGAGAGCGCTAGTTCTTCT
AAAAGCCGTTTGGAAAGGTTGGCTACTGAAATTCCATTTTTTATTAAAGATGGAATCTCACTTCCTAAGAAGATTTTGCT
GATTGATGACATCTATACAACAGGGGCAACTGTGAATCGTGTGAAACGACTTTTGGAAGAAGCAGGTGCTTTGGAAGTTA
AAACTTTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(181-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T4IRA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus mitis NCTC 12261

80

100

0.8
  comFC/cflB Streptococcus pneumoniae TIGR4

79.091

100

0.791
  comFC/cflB Streptococcus mitis SK321

79.091

100

0.791
  comFC/cflB Streptococcus pneumoniae D39

79.091

100

0.791
  comFC/cflB Streptococcus pneumoniae R6

79.091

100

0.791
  comFC/cflB Streptococcus pneumoniae Rx1

79.091

100

0.791
  comFC Bacillus subtilis subsp. subtilis str. 168

35.242

100

0.364