Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   I6H78_RS03270 Genome accession   NZ_CP066059
Coordinates   680569..682470 (-) Length   633 a.a.
NCBI ID   WP_198460020.1    Uniprot ID   A0A7T4ITX7
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 675569..687470
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS03250 (I6H78_03250) - 676701..677975 (-) 1275 WP_198460016.1 hydroxymethylglutaryl-CoA reductase, degradative -
  I6H78_RS03255 (I6H78_03255) - 677975..679147 (-) 1173 WP_198460018.1 hydroxymethylglutaryl-CoA synthase -
  I6H78_RS03260 (I6H78_03260) - 679266..679721 (-) 456 WP_044021233.1 threonine/serine exporter family protein -
  I6H78_RS03265 (I6H78_03265) - 679723..680481 (-) 759 WP_049519326.1 threonine/serine exporter family protein -
  I6H78_RS03270 (I6H78_03270) stkP 680569..682470 (-) 1902 WP_198460020.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  I6H78_RS03275 (I6H78_03275) - 682467..683207 (-) 741 WP_000401527.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  I6H78_RS03280 (I6H78_03280) rsmB 683223..684536 (-) 1314 WP_198460022.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  I6H78_RS03285 (I6H78_03285) fmt 684529..685464 (-) 936 WP_198460024.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 68851.08 Da        Isoelectric Point: 9.1506

>NTDB_id=516939 I6H78_RS03270 WP_198460020.1 680569..682470(-) (stkP) [Streptococcus oralis strain FDAARGOS_1021]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLSDRYQSVSEMYVDLSTSLSYNRRNEPKLVFDDASKADTKTLPKVPQSTLTSIPKAPAQEERPQPK
KPTQPVAEPAPAPKPAKKRKFKARYMILLASLLLVAASLVWILSRTPATIAIPNVAGQTVAEAKEALKKSKFEAGEEKSE
ASDTVAEGRVIRTDPEAGSGRKEGTKVNLIVSSGKQSFQLSNYVGRKYTEVVAELKEKKVPENLIKMEEEESNESEPGTV
LRQTPASGSTYDLSKATTITLTVAKKVTSVSMPNYIGSSLEFTKNNLTQIVGVKEANIEVVEVSTAPEGTAEGTVVSQTP
RAGEQVDLASTRIKLSIYKPKTPPSTSSSNPAQRGNQGSPTSPNQGNQQGNQQGNTPSSSSSNSEGTHESSRD

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=516939 I6H78_RS03270 WP_198460020.1 680569..682470(-) (stkP) [Streptococcus oralis strain FDAARGOS_1021]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTGTCAAGCAGATTGGTCGAGGAGGCATGGCAGATGTTTA
CTTGGCCAAGGATTTGATCCTAGACGGGGAAGAAGTGGCAGTGAAGGTCCTGAGGACCAACTACCAGACGGACCCGATTG
CTGTGGCACGTTTCCAGCGTGAAGCGAGGGCCATGGCGGATCTGGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTACCTAGCTATGGAATACGTAGCAGGTCTTGACCTCAAGCGTTATATCAAAGAACACTATCC
TCTTTCAAATGAAGAAGCAGTTCGGATCATGGGGCAAATCCTCTTGGCCATGCGCTTAGCCCATACTCGAGGAATTGTTC
ACCGGGATTTGAAACCTCAAAATATCCTCTTGACACCAGACGGCACAGCTAAGGTCACGGACTTTGGGATTGCAGTAGCC
TTTGCGGAGACCAGTCTGACCCAGACGAACTCAATGCTGGGTTCTGTTCATTATTTGTCACCTGAGCAAGCACGTGGTTC
TAAAGCGACCTTCCAGAGTGATATCTATGCAATGGGGATTATCTTCTATGAGATGCTGACGGGACATATCCCTTATGATG
GGGATAGTGCGGTTACGATTGCCCTCCAGCATTTCCAGAAGCCACTACCGTCCGTCATAGCTGAAAATCCATCTGTCCCT
CAGGCTTTAGAAAATGTTGTCATCAAGGCAACTGCTAAGAAGTTGTCAGACCGTTATCAGTCTGTTTCAGAAATGTATGT
GGACTTGTCAACTAGCTTGTCTTATAATCGTCGGAATGAACCGAAACTGGTCTTTGACGATGCGAGTAAGGCAGACACTA
AGACTTTACCTAAAGTTCCACAAAGTACACTGACATCGATTCCTAAAGCTCCGGCGCAGGAAGAACGCCCTCAGCCAAAG
AAACCAACTCAACCAGTGGCAGAGCCGGCTCCAGCGCCAAAGCCAGCCAAGAAACGGAAGTTTAAGGCTCGCTATATGAT
TCTTTTGGCCAGTCTTCTATTGGTTGCAGCCTCTTTGGTCTGGATTTTGTCAAGAACACCAGCAACGATTGCTATTCCTA
ACGTGGCTGGACAAACCGTTGCAGAGGCTAAGGAAGCTCTTAAAAAATCCAAGTTTGAAGCCGGTGAAGAAAAGTCAGAA
GCCAGCGATACCGTAGCAGAAGGACGTGTTATTCGAACGGATCCAGAAGCTGGTAGTGGCCGAAAAGAAGGAACCAAGGT
CAATTTGATCGTTTCTTCTGGTAAGCAATCCTTCCAATTAAGCAATTATGTCGGACGCAAGTATACGGAAGTTGTAGCTG
AACTCAAGGAGAAGAAGGTTCCTGAAAATCTAATCAAGATGGAAGAGGAAGAATCCAATGAAAGCGAACCTGGAACCGTC
CTCAGACAGACCCCTGCATCGGGTTCGACCTATGATCTCTCAAAAGCCACTACGATTACTTTAACAGTAGCTAAGAAGGT
GACTAGTGTCAGCATGCCGAACTACATTGGTTCAAGTCTCGAGTTTACAAAGAATAACTTGACTCAGATTGTCGGTGTGA
AGGAAGCAAATATTGAGGTTGTAGAAGTATCGACTGCTCCTGAAGGAACGGCAGAAGGAACTGTTGTAAGCCAAACGCCA
AGAGCAGGAGAACAGGTTGATCTTGCAAGTACGCGTATCAAACTTTCTATCTACAAACCAAAAACACCACCATCAACTTC
ATCCTCTAACCCTGCCCAACGTGGGAACCAGGGTTCTCCTACAAGTCCAAACCAGGGGAACCAACAAGGAAATCAACAAG
GGAATACTCCTTCTAGCAGTTCATCCAATAGTGAAGGAACTCACGAAAGTTCTCGAGATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(371-432)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T4ITX7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

78.669

92.575

0.728
  stkP Streptococcus pneumoniae D39

78.328

92.575

0.725
  stkP Streptococcus pneumoniae R6

78.328

92.575

0.725
  stkP Streptococcus pneumoniae Rx1

78.157

92.575

0.724
  pknB Streptococcus mutans UA159

56.153

91.153

0.512
  stkP/pknB Streptococcus salivarius strain HSISS4

52.445

93.681

0.491