Detailed information NTG0516933

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: I6H78_RS01790
• Genome accession: NZ_CP066059
• Coordinates: 375510..377750 (-)
• Length: 746 a.a.
• NCBI ID: WP_198459754.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain FDAARGOS_1021
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 370510..382750

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H78_RS01760 (I6H78_01760)	rplT	371844..372203 (-)	360	WP_000124830.1	50S ribosomal protein L20	-
I6H78_RS01765 (I6H78_01765)	rpmI	372255..372455 (-)	201	WP_001125942.1	50S ribosomal protein L35	-
I6H78_RS01770 (I6H78_01770)	infC	372488..373018 (-)	531	WP_000848184.1	translation initiation factor IF-3	-
I6H78_RS01775 (I6H78_01775)	-	373325..374509 (-)	1185	WP_198459751.1	hypothetical protein	-
I6H78_RS01780 (I6H78_01780)	-	374513..375100 (-)	588	WP_198459752.1	ATP-binding cassette domain-containing protein	-
I6H78_RS01785 (I6H78_01785)	-	375133..375321 (-)	189	WP_061419442.1	hypothetical protein	-
I6H78_RS01790 (I6H78_01790)	comEC/celB	375510..377750 (-)	2241	WP_198459754.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6H78_RS01795 (I6H78_01795)	comEA/celA/cilE	377734..378384 (-)	651	WP_198459755.1	helix-hairpin-helix domain-containing protein	Machinery gene
I6H78_RS01800 (I6H78_01800)	-	378451..379020 (-)	570	WP_198459756.1	GNAT family N-acetyltransferase	-
I6H78_RS01805 (I6H78_01805)	ald	379197..380309 (+)	1113	WP_198459757.1	alanine dehydrogenase	-
I6H78_RS01810 (I6H78_01810)	tnpA	380469..380932 (-)	464	Protein_360	IS200/IS605 family transposase	-
I6H78_RS01815 (I6H78_01815)	-	381122..382108 (-)	987	WP_125425819.1	PhoH family protein	-
I6H78_RS01820 (I6H78_01820)	-	382189..382404 (-)	216	WP_198459758.1	YozE family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84552.79 Da
• Isoelectric Point: 8.7852

>NTDB_id=516933 I6H78_RS01790 WP_198459754.1 375510..377750(-) (comEC/celB) [Streptococcus oralis strain FDAARGOS_1021]
MSQWIKNSPIPLIYLSFLLLWLYYAIFGASYLALLGFVFLLVCLFFQFPWKSAGKVLAICGVFGFWFLFQNWQQTQVSQK
LVDSVEKVRILPDTIKVNGDSLSFRGKADGRTFQVYYKLQSEEEKEQFQALTDLHEIELEGKLSEPEGQRNFGGFDYQAY
LKTQGIYQTLTIKNIQSLKQVSSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDAFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTILVLFII
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDVVFLPLLSI
LFILSFVYPVTQFNFVFEWLEGVIRLVSQLASRPLVFGQPNAWLLILLLVSLALVYDMRKNIKRLAGFSLFIVCLFFLTK
HPLENEITMLDVGQGESIFLRDVTSKTILIDVGGKVEASKKIGVWQEKVTTSNAQRTLIPYLKSRGVDKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLTQKEFVAELEASQTKVRSVTVGENLPIFGSQLEVLSPRQIGDDDRDGSLVLYGKL
LDKHFLFTGNLKEKGEKDLLKQYPDLEVEVLKAGQHGAKTSSNPAFLENLKPEITLISVGKNNLAKLPHQETLTRLETIK
SKIYRTDQQGAIRFKGWNSWRMESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=516933 I6H78_RS01790 WP_198459754.1 375510..377750(-) (comEC/celB) [Streptococcus oralis strain FDAARGOS_1021]
ATGTCACAGTGGATTAAGAATTCCCCTATCCCCCTAATCTATCTGAGTTTTCTGTTACTCTGGCTTTACTATGCCATTTT
TGGAGCGTCCTATCTCGCACTGCTAGGTTTTGTTTTTTTGCTTGTCTGTCTCTTTTTCCAATTTCCTTGGAAATCGGCTG
GAAAAGTTCTAGCGATTTGTGGAGTTTTTGGATTTTGGTTTCTGTTTCAAAATTGGCAACAGACACAAGTTAGTCAAAAG
TTAGTGGATTCTGTTGAGAAGGTACGGATTTTACCAGATACTATCAAAGTCAATGGAGATAGTCTGTCCTTTCGGGGCAA
GGCTGACGGCCGCACCTTCCAAGTTTACTATAAACTCCAGTCCGAGGAGGAGAAAGAGCAATTTCAAGCCTTGACAGACC
TTCATGAGATAGAACTAGAAGGAAAACTTTCAGAGCCTGAAGGTCAGAGGAATTTTGGTGGATTTGACTATCAAGCCTAT
CTAAAGACTCAAGGGATTTACCAGACATTGACTATCAAGAACATCCAGTCACTTAAACAGGTTAGCAGTTGGGATATAGG
AGAAAATCTGTCCAGTTTACGTCGAAAGGCTGTAGTTTGGATAAAGACGCACTTTCCAGATCCTATGCGCAACTATATGA
CAGGTCTTCTTTTAGGACATTTGGACACGGACTTTGAGGAGATGAATGAGCTCTATTCCAGTCTTGGAATTATCCATCTC
TTTGCCTTGTCGGGTATGCAGGTGGGCTTCTTTATGGATGCCTTTAAGAAACTCCTCTTACGATTGGGCTTGACCCAAGA
AAAGTTGAAGTGGCTGACCTATCCCTTTTCCCTTATCTATGCAGGTCTGACAGGATTTTCAGCTTCGGTCATTCGCAGTC
TCTTGCAAAAGTTACTAGCCCAACATGGTGTTAAAGGTTTGGATAATTTTGCCTTGACGATCCTTGTCCTTTTTATCATT
ATGCCCAACTTTTTCCTAACTGCAGGAGGAGTCTTGTCCTGCGCCTATGCTTTTATCTTGACCATGACAAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCCAGAGAAAGTTTGGTCATTTCTTTGGGAATATTGCCCATTCTATCCTTCTATTTTGCAG
AATTTCAGCCTTGGTCTATTCTTTTGACCTTTGTTTTTTCCTTTCTGTTTGATGTGGTATTCTTACCGCTTTTGTCCATC
TTATTCATTCTGTCTTTTGTTTACCCAGTCACTCAGTTTAACTTTGTCTTTGAGTGGTTAGAGGGCGTCATTCGCTTGGT
ATCGCAGCTGGCAAGCAGGCCTCTGGTCTTTGGTCAACCCAACGCATGGCTGTTGATTCTACTGTTAGTTTCATTAGCCT
TAGTCTATGACATGAGGAAAAACATTAAAAGACTAGCAGGATTTAGTCTCTTTATTGTGTGTCTCTTTTTCCTGACCAAG
CATCCACTTGAAAATGAAATTACCATGCTGGATGTTGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTAGTAAAAC
TATTCTCATAGATGTTGGTGGTAAGGTAGAAGCTAGTAAGAAAATCGGGGTTTGGCAAGAAAAGGTGACGACCAGCAATG
CTCAGAGAACCTTGATTCCCTATCTTAAAAGTCGAGGAGTAGACAAGATTGACCAGCTGATTTTGACCAATACAGACAAG
GAGCATGTTGGAGATTTACTAGAGGTGACCAAGGCTTTCCATGTTGGGGAGATTTTAGTATCAAAAGGAAGTCTGACACA
GAAGGAATTTGTAGCAGAATTAGAAGCAAGCCAAACCAAGGTGCGCAGTGTAACAGTAGGGGAGAACTTGCCGATTTTTG
GGAGTCAGTTAGAAGTCCTATCTCCAAGGCAGATTGGAGATGATGATCGTGATGGTTCCCTGGTTCTTTATGGAAAACTT
TTGGATAAGCACTTTCTCTTCACAGGAAATTTGAAAGAGAAGGGAGAGAAAGACTTGCTGAAGCAATACCCTGACCTAGA
GGTGGAGGTCTTGAAAGCAGGCCAGCATGGTGCTAAAACCTCATCCAATCCAGCTTTCCTAGAAAACCTCAAACCAGAAA
TTACTCTCATCTCAGTTGGAAAAAACAATCTTGCGAAACTCCCCCATCAGGAAACCTTGACTCGACTAGAAACCATCAAG
AGTAAGATTTACCGAACTGACCAGCAAGGGGCTATCCGCTTTAAAGGGTGGAATAGTTGGCGAATGGAAAGTGTTCGTTA
G

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-458)

• Domain of unknown function (DUF4131) (DUF4131) (31-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-637)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	88.472	100	0.885
comEC/celB	Streptococcus mitis NCTC 12261	88.322	99.866	0.882
comEC/celB	Streptococcus pneumoniae TIGR4	87.131	100	0.871
comEC/celB	Streptococcus pneumoniae Rx1	86.729	100	0.867
comEC/celB	Streptococcus pneumoniae D39	86.729	100	0.867
comEC/celB	Streptococcus pneumoniae R6	86.729	100	0.867
comEC	Lactococcus lactis subsp. cremoris KW2	44.804	99.33	0.445