Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   I6H78_RS00135 Genome accession   NZ_CP066059
Coordinates   26765..27613 (+) Length   282 a.a.
NCBI ID   WP_198459526.1    Uniprot ID   A0A7T4M0K1
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 21765..32613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS00120 (I6H78_00120) - 23290..24018 (+) 729 WP_198459524.1 metallophosphoesterase -
  I6H78_RS00125 (I6H78_00125) lepA 24097..25920 (+) 1824 WP_001047158.1 translation elongation factor 4 -
  I6H78_RS00130 (I6H78_00130) - 26059..26682 (+) 624 WP_198459525.1 hypothetical protein -
  I6H78_RS00135 (I6H78_00135) dprA/cilB/dalA 26765..27613 (+) 849 WP_198459526.1 DNA-processing protein DprA Machinery gene
  I6H78_RS00140 (I6H78_00140) topA 27731..29818 (+) 2088 WP_198459527.1 type I DNA topoisomerase -
  I6H78_RS00145 (I6H78_00145) - 29925..30284 (+) 360 WP_007516860.1 YbaN family protein -
  I6H78_RS00150 (I6H78_00150) - 30378..31010 (+) 633 WP_198459528.1 copper homeostasis protein CutC -
  I6H78_RS00155 (I6H78_00155) - 31054..31710 (+) 657 WP_198459529.1 MmcQ/YjbR family DNA-binding protein -

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31289.74 Da        Isoelectric Point: 5.2027

>NTDB_id=516924 I6H78_RS00135 WP_198459526.1 26765..27613(+) (dprA/cilB/dalA) [Streptococcus oralis strain FDAARGOS_1021]
MKITNYEIYKLRKAGLTNQQILTVLEYDETVDQELLLGDIAELSGCRNPAVFMERYFQIDDAQLEKEFQKFPSFSILDDC
YPWDLSEIYDAPALLFYKGNLDLLKFPKVAVVGSRSCSSQGAKSVQRVIQGLENELIVVSGLAKGIDTAAHMAALQNGGR
TIAVIGTGLDVFYPRTNKRLQEHIGNHHLVLSEYGPGEEPLKFHFPARNRIIAGLCRGVIVAEARMRSGSLITCERAMEE
GRDVFAIPGNILDGHSDGCHHLIQEGAKLISSGQDVLAEFEF

Nucleotide


Download         Length: 849 bp        

>NTDB_id=516924 I6H78_RS00135 WP_198459526.1 26765..27613(+) (dprA/cilB/dalA) [Streptococcus oralis strain FDAARGOS_1021]
ATGAAGATCACAAACTATGAGATTTACAAATTGAGAAAAGCTGGGCTGACCAATCAACAAATTTTAACTGTTCTTGAATA
CGATGAGACTGTAGATCAGGAGCTCTTGTTAGGTGACATTGCGGAACTATCGGGATGCCGTAATCCTGCTGTCTTTATGG
AACGCTATTTCCAGATAGATGATGCACAGTTGGAGAAGGAGTTTCAGAAATTTCCATCCTTTTCTATTCTTGATGACTGT
TATCCTTGGGATCTGAGTGAGATTTATGATGCTCCAGCGCTCTTGTTTTATAAAGGAAATCTGGACTTGTTGAAGTTTCC
AAAGGTTGCTGTTGTAGGGAGCCGTTCATGTTCTAGTCAGGGAGCAAAGTCGGTTCAGAGAGTCATTCAAGGTTTGGAAA
ACGAGTTAATCGTGGTCAGTGGTTTAGCCAAAGGGATTGATACGGCTGCCCATATGGCTGCACTCCAGAATGGAGGAAGA
ACAATTGCTGTCATTGGAACAGGATTGGATGTTTTTTATCCCCGCACCAATAAACGTTTGCAGGAACACATTGGCAATCA
CCATTTGGTACTTAGCGAGTACGGACCTGGTGAAGAACCCTTGAAATTTCACTTTCCAGCCCGTAATCGCATCATTGCTG
GACTGTGCCGTGGTGTGATTGTAGCAGAGGCAAGGATGCGTTCTGGTAGTCTCATCACCTGTGAGCGAGCTATGGAGGAA
GGGCGTGATGTTTTTGCCATTCCAGGAAACATTTTAGATGGCCATTCAGATGGCTGTCACCACCTGATCCAAGAGGGAGC
AAAACTGATTTCCAGCGGGCAAGATGTGCTAGCTGAGTTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(75-271)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(3-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T4M0K1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

90.426

100

0.904
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

90.071

100

0.901
  dprA/cilB/dalA Streptococcus pneumoniae D39

90.071

100

0.901
  dprA/cilB/dalA Streptococcus pneumoniae R6

90.071

100

0.901
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

90.071

100

0.901
  dprA/cilB/dalA Streptococcus mitis SK321

89.362

100

0.894
  dprA Streptococcus mutans UA159

60.357

99.291

0.599
  dprA Lactococcus lactis subsp. cremoris KW2

54.286

99.291

0.539