Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   I6H72_RS04390 Genome accession   NZ_CP066055
Coordinates   892615..893370 (-) Length   251 a.a.
NCBI ID   WP_003070299.1    Uniprot ID   F9P4C7
Organism   Streptococcus constellatus strain FDAARGOS_1015     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 887615..898370
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H72_RS04370 (I6H72_04370) - 888045..889277 (-) 1233 WP_198458369.1 cysteine desulfurase -
  I6H72_RS04375 (I6H72_04375) sufD 889294..890556 (-) 1263 WP_198458370.1 Fe-S cluster assembly protein SufD -
  I6H72_RS04380 (I6H72_04380) sufC 890596..891366 (-) 771 WP_006267171.1 Fe-S cluster assembly ATPase SufC -
  I6H72_RS04385 (I6H72_04385) - 891458..892624 (-) 1167 WP_022524656.1 glycosyltransferase family 4 protein -
  I6H72_RS04390 (I6H72_04390) mecA 892615..893370 (-) 756 WP_003070299.1 adaptor protein MecA Regulator
  I6H72_RS04395 (I6H72_04395) - 893495..894337 (-) 843 WP_003070301.1 undecaprenyl-diphosphate phosphatase -
  I6H72_RS04400 (I6H72_04400) - 894404..896280 (-) 1877 Protein_878 DUF2207 family protein -
  I6H72_RS04405 (I6H72_04405) - 896408..897973 (+) 1566 WP_198458371.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29014.77 Da        Isoelectric Point: 4.1166

>NTDB_id=516851 I6H72_RS04390 WP_003070299.1 892615..893370(-) (mecA) [Streptococcus constellatus strain FDAARGOS_1015]
MEMKQISDTTIKITIKLEDLEERGMEMADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDRLDVFVTKSKI
DKNLNFDDLADLPDVEELSQMSPDEFLKTLEKNIFEKSKDDIEAVRSLETAEAENNMSTSDIEDQEENSDDLTQKYIYYI
LKFSSLKEAIVFSKTVDYAVNTSELYKMDGYYYLTILVDIEGHPKRYPAWLLASMREHAEDTDVTRAVLQEHGYLLLVNE
AVASLQKVKCS

Nucleotide


Download         Length: 756 bp        

>NTDB_id=516851 I6H72_RS04390 WP_003070299.1 892615..893370(-) (mecA) [Streptococcus constellatus strain FDAARGOS_1015]
ATGGAAATGAAGCAAATTAGTGATACAACGATTAAGATCACAATAAAATTAGAAGATTTAGAAGAACGTGGAATGGAGAT
GGCAGATTTTCTCGTTCCGCAAGAAAAGACAGAAGAGTTTTTCTATGCAATTTTAGATGAGTTGGAAATGCCCGAGAGTT
TTTTGGATAGCGGTATGCTCAGTTTTCGTGTAACTCCTAAACCAGACCGACTGGATGTTTTTGTCACCAAGTCTAAGATT
GATAAGAATCTGAACTTTGATGATTTGGCAGATTTACCAGATGTAGAAGAGCTGTCTCAAATGTCTCCAGATGAATTTTT
AAAGACATTAGAAAAAAATATTTTTGAGAAAAGCAAAGACGATATTGAAGCTGTTCGGTCTTTGGAAACGGCAGAAGCAG
AAAATAATATGAGCACTTCTGACATAGAAGATCAAGAAGAAAACAGTGACGACCTTACTCAAAAATATATCTATTATATC
TTGAAATTTTCCAGCTTGAAAGAAGCGATTGTCTTTTCTAAAACAGTAGACTATGCTGTTAACACTTCGGAGTTGTACAA
AATGGATGGTTACTATTATTTAACAATCTTGGTTGATATTGAAGGACATCCTAAGCGTTATCCAGCTTGGCTTTTGGCTT
CTATGCGTGAACATGCAGAAGACACAGATGTGACAAGAGCTGTTTTACAAGAGCATGGTTATTTATTACTTGTCAACGAG
GCGGTTGCTAGTCTTCAAAAGGTTAAATGCTCATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9P4C7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

66.532

98.805

0.657
  mecA Streptococcus pneumoniae D39

66.532

98.805

0.657
  mecA Streptococcus pneumoniae R6

66.532

98.805

0.657
  mecA Streptococcus pneumoniae TIGR4

66.129

98.805

0.653
  mecA Streptococcus mutans UA159

50

98.805

0.494
  mecA Streptococcus thermophilus LMD-9

46.304

100

0.474
  mecA Streptococcus thermophilus LMG 18311

45.914

100

0.47