Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   I6H72_RS04225 Genome accession   NZ_CP066055
Coordinates   856042..857925 (-) Length   627 a.a.
NCBI ID   WP_020997630.1    Uniprot ID   -
Organism   Streptococcus constellatus strain FDAARGOS_1015     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 851042..862925
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H72_RS04195 (I6H72_04195) - 851184..851501 (+) 318 WP_006269734.1 DUF960 domain-containing protein -
  I6H72_RS04200 (I6H72_04200) - 851621..852013 (-) 393 WP_020997633.1 S1 RNA-binding domain-containing protein -
  I6H72_RS04205 (I6H72_04205) - 852015..853415 (-) 1401 WP_198458350.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I6H72_RS04210 (I6H72_04210) - 853455..854087 (-) 633 WP_198458351.1 response regulator transcription factor -
  I6H72_RS04215 (I6H72_04215) - 854089..855084 (-) 996 WP_198458352.1 sensor histidine kinase -
  I6H72_RS04220 (I6H72_04220) liaF 855081..855779 (-) 699 WP_198458353.1 cell wall-active antibiotics response protein LiaF -
  I6H72_RS04225 (I6H72_04225) stkP 856042..857925 (-) 1884 WP_020997630.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  I6H72_RS04230 (I6H72_04230) - 857922..858662 (-) 741 WP_003028411.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  I6H72_RS04235 (I6H72_04235) rsmB 858681..859994 (-) 1314 WP_198458354.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  I6H72_RS04240 (I6H72_04240) fmt 859984..860919 (-) 936 WP_198458355.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 67999.20 Da        Isoelectric Point: 9.6707

>NTDB_id=516849 I6H72_RS04225 WP_020997630.1 856042..857925(-) (stkP) [Streptococcus constellatus strain FDAARGOS_1015]
MIQVGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKEHAPLSNEEAVRIMGQILLAMRLAHTHGIVHRDLKPQNVLLTPDGDAKVTDFGIAVA
FAETSLTQTNSMLGTVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPNVP
QPLENVVIKATAKKLTDRYQSVAEMYVDLSSCLSADRRNEKKLVFDDTAKADTKTLPKVSQNTLISASKPTTPTPIKETV
SSNSQPTTKPKTKKKRRLRTRYKVLLSAVVLVIAALVALVYLSPSNVKIPDVTGKTVAQARSAIEAAGLKVGKEKDEYSD
SAKKDSVIRTNPQAGTQRREGSTVDLIVSKGPKTFTMEDYSGQKKADAINSLVQKYKVSKGLIKIEEVESSDYAAGTVVS
QTPAAGSTYDLTSKNRITLKVAKTVSSVTMPSYIGSTYEFAYNNLTEVIGVQGANVEKRIVTTAPAGTQAHTIIKQSPEA
KRPLNLKNDRIVLYVYEPKTEESSTSESSSQSGSSSNKNSPSSSSSSSSGNDGSSSKTPDTSASASN

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=516849 I6H72_RS04225 WP_020997630.1 856042..857925(-) (stkP) [Streptococcus constellatus strain FDAARGOS_1015]
ATGATTCAAGTCGGCAAGATATTTGCCGGGCGATATAGAATCATCAAACAAATTGGGCGAGGTGGCATGGCAGATGTTTA
CTTGGCCAAAGATTTGATTTTAGACGGGGAAGAAGTCGCGGTGAAAGTTCTAAGAACGAATTACCAGACGGATCCGATTG
CTGTGGCGCGCTTTCAAAGAGAGGCGCGAGCGATGGCAGACTTGGATCATCCTCATATTGTCCGGATTACCGATATTGGA
GAAGAAGAAGGTCAGCAATATCTAGCAATGGAGTATGTGGCTGGGCTTGACTTAAAACGCTATATTAAAGAGCATGCTCC
TTTATCTAATGAAGAAGCGGTTCGGATTATGGGACAAATTCTTTTGGCAATGCGTTTGGCGCATACGCATGGAATTGTTC
ATCGTGATTTGAAGCCACAAAATGTCCTTTTAACTCCAGATGGCGATGCAAAAGTAACGGACTTTGGAATTGCAGTAGCT
TTTGCTGAAACGAGCCTGACGCAAACAAATTCAATGCTGGGAACTGTGCATTATCTATCACCAGAACAAGCGCGTGGTTC
AAAAGCGACCGTTCAAAGCGATATTTACGCTATGGGGATCATTTTCTATGAAATGTTGACAGGACATATCCCTTATGATG
GGGATAGTGCTGTCACAATTGCTTTGCAACATTTCCAAAAGCCTCTTCCTTCTGTGATTGCTGAAAATCCAAATGTGCCA
CAGCCTCTAGAAAATGTAGTCATCAAGGCAACGGCTAAAAAATTAACAGATCGTTATCAATCTGTTGCAGAAATGTATGT
GGATTTATCAAGCTGCTTATCCGCAGATCGCCGAAATGAGAAAAAGTTGGTTTTTGATGATACTGCCAAAGCAGATACCA
AGACGCTTCCTAAAGTGTCACAAAATACCTTAATTTCTGCAAGCAAACCAACTACTCCTACGCCTATAAAAGAAACAGTC
AGTAGTAATTCTCAACCCACAACCAAGCCAAAAACAAAGAAAAAACGTCGTTTAAGAACGCGTTATAAAGTGTTGTTGTC
GGCAGTAGTCTTAGTTATTGCAGCTTTGGTGGCTTTAGTCTATTTGAGTCCCTCAAATGTAAAAATACCAGATGTTACTG
GAAAAACCGTTGCGCAAGCACGTTCCGCGATTGAAGCTGCAGGTTTGAAAGTTGGCAAGGAGAAAGACGAATACAGTGAT
TCTGCTAAGAAAGATTCTGTCATTCGTACGAATCCACAAGCGGGAACACAACGTCGCGAAGGAAGCACAGTAGATTTGAT
TGTCTCAAAAGGGCCGAAAACATTTACTATGGAAGATTATAGCGGTCAAAAAAAAGCAGATGCTATCAACAGTTTGGTGC
AAAAATACAAAGTTTCAAAGGGCTTGATTAAAATTGAAGAAGTCGAAAGTAGTGACTATGCAGCAGGAACTGTTGTTAGT
CAGACGCCTGCAGCAGGTAGTACGTATGATTTGACTTCAAAAAATCGGATTACGTTAAAAGTAGCGAAGACGGTTTCAAG
TGTTACAATGCCAAGTTATATAGGTTCCACTTATGAATTTGCCTATAATAACCTTACCGAAGTTATTGGCGTTCAAGGAG
CTAATGTTGAAAAACGAATAGTTACAACAGCTCCAGCAGGAACACAGGCACACACGATTATTAAACAAAGCCCAGAAGCA
AAGAGGCCTCTAAATTTAAAAAATGATCGTATTGTCTTATATGTATATGAGCCAAAAACTGAAGAATCATCTACATCTGA
AAGTAGTTCGCAATCTGGAAGCAGTTCAAATAAAAATAGTCCATCATCTAGTAGTTCGTCGAGTAGCGGTAACGATGGAT
CAAGTTCGAAAACACCAGACACAAGCGCTAGTGCAAGTAATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(436-503)

PASTA domain (PASTA)

(508-576)

PASTA domain (PASTA)

(367-430)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

66.209

92.982

0.616
  stkP Streptococcus pneumoniae D39

65.866

92.982

0.612
  stkP Streptococcus pneumoniae R6

65.866

92.982

0.612
  stkP Streptococcus pneumoniae Rx1

65.695

92.982

0.611
  pknB Streptococcus mutans UA159

58.632

93.301

0.547
  stkP/pknB Streptococcus salivarius strain HSISS4

58.519

86.124

0.504