Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   KW2_RS09665 Genome accession   NC_022369
Coordinates   2027062..2028939 (-) Length   625 a.a.
NCBI ID   WP_021037829.1    Uniprot ID   -
Organism   Lactococcus cremoris subsp. cremoris KW2     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 2022062..2033939
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KW2_RS09635 (kw2_1938) - 2022485..2023165 (-) 681 WP_011676892.1 5'-methylthioadenosine/adenosylhomocysteine nucleosidase -
  KW2_RS09640 (kw2_1939) macP 2023193..2023471 (-) 279 WP_011676893.1 cell wall synthase accessory phosphoprotein MacP -
  KW2_RS09645 (kw2_1940) - 2023464..2024048 (-) 585 WP_021037826.1 NUDIX hydrolase -
  KW2_RS09650 (kw2_1941) glmU 2024149..2025525 (-) 1377 WP_021037827.1 bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU -
  KW2_RS09655 (kw2_1942) proC 2025747..2026538 (+) 792 WP_021037828.1 pyrroline-5-carboxylate reductase -
  KW2_RS09660 (kw2_1943) rpsO 2026622..2026891 (-) 270 WP_010906184.1 30S ribosomal protein S15 -
  KW2_RS09665 (kw2_1944) pknB 2027062..2028939 (-) 1878 WP_021037829.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  KW2_RS09670 (kw2_1945) - 2028939..2029715 (-) 777 WP_011676898.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  KW2_RS09675 (kw2_1946) rsmB 2029838..2031112 (-) 1275 WP_021037830.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  KW2_RS09680 (kw2_1947) - 2031306..2031812 (-) 507 WP_011676957.1 Asp23/Gls24 family envelope stress response protein -
  KW2_RS09685 (kw2_1948) - 2031822..2032010 (-) 189 WP_011676958.1 DUF2273 domain-containing protein -
  KW2_RS09690 (kw2_1949) amaP 2032021..2032581 (-) 561 WP_021037831.1 alkaline shock response membrane anchor protein AmaP -
  KW2_RS09695 (kw2_1950) - 2032609..2032851 (-) 243 WP_011676960.1 GlsB/YeaQ/YmgE family stress response membrane protein -

Sequence

Protein


Download         Length: 625 a.a.        Molecular weight: 67376.59 Da        Isoelectric Point: 4.8769

>NTDB_id=51684 KW2_RS09665 WP_021037829.1 2027062..2028939(-) (pknB) [Lactococcus cremoris subsp. cremoris KW2]
MIQIGKIFADRYRIIKEIGRGGMANVYQGEDTFLGDRKVAIKVLRSNFENDDIAIARFQREAFAMAELSHPNIVGISDVG
EFESQQYIVMEFVDGMTLKQYINQNAPLANDEAIEIITEILSAMDMAHSHGIIHRDLKPQNVLVSSSGTVKVTDFGIAKA
LSETSLTQTNTMFGSVHYLSPEQARGSNATVQSDIYAIGIILFELLTGQIPFDGDSAVAIALKHFQENIPSIINLNPEVP
QALENVVIKATAKDINNRYADVEEMMTDVATSTSLDRRGEEKLVFNKDHDETKIMPANLINPYDTKPLIDKKTDDQEKAQ
SESSTTENNKNKNKKSKKGLIISLVVLLLVIGGGAFAWAVSTPTNVKVPNVTNNLTLDQAKKKIKAADLKVGTVHKQQST
TVAEGKVIKTDPASGATVRSKSSVDIYVSSGNENIIKMKDFVGEKIDDAMATLLKDYGIDESQVVQTSVPSDSYAAGTII
KQTPKKGSSFDVTSGDKITFEVSSGKQIAIPSYTNQDAESYKAILKQAGFTNVTLNYIDTPGSPTGWVFGVTPTVGELVS
IDAPIVVKVTQAVEQSSSESSVSTSETSTSESTSASSSTTSSSSSSTTEQSPENSTSSSTTTSHS

Nucleotide


Download         Length: 1878 bp        

>NTDB_id=51684 KW2_RS09665 WP_021037829.1 2027062..2028939(-) (pknB) [Lactococcus cremoris subsp. cremoris KW2]
ATGATTCAAATCGGTAAAATCTTTGCCGATCGTTATCGGATTATCAAAGAAATCGGACGTGGGGGAATGGCAAACGTTTA
TCAAGGAGAAGATACTTTCCTTGGTGATCGAAAAGTTGCAATTAAAGTACTTCGTTCTAATTTTGAAAATGATGACATTG
CAATCGCTCGTTTTCAAAGAGAAGCTTTTGCGATGGCGGAACTCTCTCATCCGAATATCGTAGGTATTTCTGACGTCGGT
GAATTCGAAAGTCAACAATACATTGTAATGGAATTTGTTGATGGTATGACGCTCAAACAATACATCAACCAAAATGCTCC
TCTAGCTAATGATGAAGCCATTGAAATTATTACAGAAATTCTATCAGCAATGGATATGGCTCATTCACATGGAATTATTC
ACCGTGATTTAAAACCACAAAATGTTTTAGTTTCAAGTAGTGGAACGGTAAAAGTAACAGATTTCGGAATTGCAAAGGCC
CTTTCTGAAACTTCACTCACTCAAACAAATACGATGTTTGGCTCAGTTCATTATCTATCACCTGAACAAGCGCGTGGTTC
AAATGCTACTGTACAATCAGACATTTATGCCATTGGGATTATTTTATTTGAGCTTTTAACAGGTCAAATACCTTTTGATG
GGGATTCAGCCGTAGCAATTGCCCTCAAACATTTCCAAGAAAATATTCCAAGCATCATAAATCTCAACCCAGAAGTTCCG
CAAGCATTGGAAAATGTCGTCATCAAAGCAACAGCAAAAGATATCAACAATCGATATGCTGATGTTGAAGAAATGATGAC
AGATGTAGCTACTTCGACTAGTCTTGATCGACGTGGGGAAGAAAAATTAGTTTTCAACAAGGACCATGATGAAACAAAAA
TCATGCCTGCCAATCTAATTAATCCTTATGATACTAAGCCTTTGATTGATAAGAAAACAGATGATCAGGAAAAAGCGCAA
TCAGAATCATCAACTACAGAAAACAATAAGAATAAAAATAAAAAGTCTAAAAAAGGATTGATTATCAGTCTTGTTGTTCT
CCTTCTTGTCATTGGTGGTGGAGCCTTTGCATGGGCTGTTTCTACACCGACAAATGTTAAGGTTCCTAATGTGACTAATA
ACTTAACATTGGATCAAGCGAAGAAAAAGATTAAAGCAGCTGATCTTAAGGTGGGAACGGTTCATAAACAACAAAGCACA
ACCGTTGCAGAAGGTAAAGTGATTAAAACTGATCCAGCAAGTGGGGCTACCGTAAGGTCTAAAAGTTCTGTTGATATTTA
CGTTTCATCTGGAAATGAAAATATTATCAAAATGAAAGACTTTGTTGGTGAAAAAATTGATGATGCAATGGCCACTCTGC
TTAAAGATTATGGTATTGATGAAAGTCAAGTGGTCCAAACCTCTGTCCCTAGTGATTCTTATGCCGCAGGTACAATCATT
AAACAAACACCTAAAAAGGGTTCTAGTTTTGATGTGACAAGTGGTGATAAAATTACATTTGAAGTTTCAAGTGGAAAACA
AATTGCCATTCCATCTTACACTAATCAGGATGCTGAAAGCTATAAAGCAATTTTGAAACAAGCTGGCTTCACTAATGTTA
CTTTAAACTATATTGATACTCCAGGAAGTCCGACAGGATGGGTATTTGGAGTTACTCCAACTGTTGGTGAATTGGTTTCG
ATAGATGCCCCAATTGTTGTTAAGGTTACTCAGGCAGTTGAGCAATCATCCTCAGAATCTTCTGTTTCTACATCAGAAAC
ATCAACTTCTGAATCAACATCAGCTTCAAGCTCAACAACGAGCTCGTCTTCTTCAAGTACAACTGAGCAATCGCCAGAAA
ATTCTACTTCAAGTTCGACAACAACATCACATAGTTAA

Domains

Predicted by InterProScan.

PASTA domain (PASTA)

(509-570)

PASTA domain (PASTA)

(366-429)

PASTA domain (PASTA)

(436-503)

Protein kinase domain (Pkinase)

(12-259)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

48.27

92.48

0.446
  stkP/pknB Streptococcus salivarius strain HSISS4

49.27

87.68

0.432
  stkP Streptococcus pneumoniae TIGR4

46.053

85.12

0.392
  stkP Streptococcus pneumoniae D39

45.865

85.12

0.39
  stkP Streptococcus pneumoniae R6

45.865

85.12

0.39
  stkP Streptococcus pneumoniae Rx1

45.677

85.12

0.389

Multiple sequence alignment