NTDB

Overview

Name	dprA/cilB/dalA	Type	Machinery gene
Locus tag	I6I32_RS09510	Genome accession	NZ_CP066041
Coordinates	1986812..1987660 (+)	Length	282 a.a.
NCBI ID	WP_084859836.1	Uniprot ID	A0A1X1HTU0
Organism	Streptococcus oralis strain FDAARGOS_1075
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1981812..1992660

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I32_RS09495 (I6I32_09495)	-	1983334..1984062 (+)	729	WP_084921810.1	metallophosphoesterase family protein	-
I6I32_RS09500 (I6I32_09500)	lepA	1984141..1985964 (+)	1824	WP_049505907.1	translation elongation factor 4	-
I6I32_RS09505 (I6I32_09505)	-	1986105..1986728 (+)	624	WP_084859835.1	hypothetical protein	-
I6I32_RS09510 (I6I32_09510)	dprA/cilB/dalA	1986812..1987660 (+)	849	WP_084859836.1	DNA-processing protein DprA	Machinery gene
I6I32_RS09515 (I6I32_09515)	topA	1987778..1989865 (+)	2088	WP_057489171.1	type I DNA topoisomerase	-
I6I32_RS09520 (I6I32_09520)	-	1989972..1990331 (+)	360	WP_001237224.1	YbaN family protein	-
I6I32_RS09525 (I6I32_09525)	-	1990425..1991057 (+)	633	WP_198464612.1	copper homeostasis protein CutC	-
I6I32_RS09530 (I6I32_09530)	-	1991101..1991757 (+)	657	WP_198464613.1	MmcQ/YjbR family DNA-binding protein	-

Sequence

Protein

Download Length: 282 a.a. Molecular weight: 31273.78 Da Isoelectric Point: 5.2027

                                >NTDB_id=516686 I6I32_RS09510 WP_084859836.1 1986812..1987660(+) (dprA/cilB/dalA) [Streptococcus oralis strain FDAARGOS_1075]

MKITNYDIYKLRKAGLTNQQILTVLEYDETVDQELLLGEIAEISGCRNPAVFMERYFQIDDAQLEKEFQKFPSFSILDDC

YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRSCSSQGAKSVQKIIQGLENELIVVSGLAKGIDTAAHMAALQNGGR

TIAVIGTGLDVFYPRANKRLQEHIGNHHLVLSEYGPGEEPLKFHFPARNRIIAGLCRGVIVAEARMRSGSLITCERAMEE

GRDVFAIPGNILDGHSDGCHHLIQEGAKLISSGQDVLAEFEF

Nucleotide

Download Length: 849 bp

                                >NTDB_id=516686 I6I32_RS09510 WP_084859836.1 1986812..1987660(+) (dprA/cilB/dalA) [Streptococcus oralis strain FDAARGOS_1075]

ATGAAGATTACAAACTATGATATTTACAAATTAAGAAAAGCAGGTTTGACCAATCAACAGATTTTAACTGTCCTTGAATA

CGATGAGACTGTAGATCAGGAGCTCTTGCTAGGTGAGATTGCAGAAATATCTGGGTGTCGTAATCCTGCAGTCTTTATGG

AACGCTATTTCCAGATAGATGATGCACAGTTGGAGAAGGAGTTTCAGAAATTTCCATCCTTTTCTATTCTTGATGACTGT

TATCCTTGGGATCTGAGTGAGATTTATGATGCTCCAGTGCTCTTGTTTTACAAAGGGAATCTGGACTTATTGAAATTTCC

CAAGGTTGCTGTTGTGGGGAGTCGTTCTTGTTCGAGCCAAGGAGCTAAGTCAGTCCAGAAAATTATCCAAGGTTTAGAAA

ACGAGTTAATCGTGGTCAGTGGTTTAGCCAAAGGGATTGATACAGCTGCCCATATGGCTGCACTCCAGAATGGAGGAAGA

ACAATTGCTGTCATTGGAACAGGATTGGATGTTTTCTATCCCCGCGCCAATAAACGTTTGCAGGAACACATTGGAAATCA

CCATTTGGTACTTAGCGAGTACGGACCTGGTGAGGAACCCTTGAAATTTCACTTTCCAGCTCGTAATCGAATCATAGCAG

GACTATGTCGAGGGGTCATTGTAGCAGAGGCAAGGATGCGTTCTGGTAGTCTTATTACTTGTGAGCGAGCTATGGAAGAA

GGGCGTGATGTCTTTGCCATTCCAGGAAACATTTTAGATGGGCATTCAGATGGCTGTCACCACCTGATTCAAGAGGGAGC

AAAGCTGATTTCCAGCGGTCAAGATGTGTTGGCTGAGTTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(75-271)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(3-64)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A1X1HTU0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	90.78	100	0.908
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	90.426	100	0.904
dprA/cilB/dalA	Streptococcus pneumoniae D39	90.426	100	0.904
dprA/cilB/dalA	Streptococcus pneumoniae R6	90.426	100	0.904
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	90.426	100	0.904
dprA/cilB/dalA	Streptococcus mitis SK321	90.426	100	0.904
dprA	Streptococcus mutans UA159	61.071	99.291	0.606
dprA	Lactococcus lactis subsp. cremoris KW2	55.714	99.291	0.553

Detailed information NTG0516686