Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   I6I32_RS09045 Genome accession   NZ_CP066041
Coordinates   1893706..1894446 (+) Length   246 a.a.
NCBI ID   WP_198465085.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1075     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1888706..1899446
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I32_RS09035 (I6I32_09035) - 1889546..1892059 (+) 2514 WP_198464578.1 MBL fold metallo-hydrolase -
  I6I32_RS09040 (I6I32_09040) - 1892105..1893583 (-) 1479 WP_000789703.1 oligosaccharide flippase family protein -
  I6I32_RS09045 (I6I32_09045) mecA 1893706..1894446 (+) 741 WP_198465085.1 adaptor protein MecA Regulator
  I6I32_RS09050 (I6I32_09050) - 1894594..1895880 (+) 1287 WP_198464579.1 homoserine dehydrogenase -
  I6I32_RS09055 (I6I32_09055) thrB 1895882..1896751 (+) 870 WP_198464580.1 homoserine kinase -
  I6I32_RS09060 (I6I32_09060) msrB 1896965..1897903 (+) 939 WP_084857679.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28655.41 Da        Isoelectric Point: 4.0929

>NTDB_id=516684 I6I32_RS09045 WP_198465085.1 1893706..1894446(+) (mecA) [Streptococcus oralis strain FDAARGOS_1075]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAQMSPDEFLKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQEDKETENKKEPYIYYILRFS
SLADLVAFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVLN
LQKIRS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=516684 I6I32_RS09045 WP_198465085.1 1893706..1894446(+) (mecA) [Streptococcus oralis strain FDAARGOS_1075]
ATGAAGATGAAACAAATTAGTGATACAACACTGAAAATCACGATGACTTTAGATGATTTGATGGATCGAGGAATGGAGAT
TGCAGACTTTCTCGTTCCTCAGGAAAAAACCGAAGAGTTTTTCTATGCTATTTTAGATGAGTTAGAGATGCCAGACAATT
TCTTGGATAGTGGCATGCTGAGTTTCCGCGTGACGCCAAAACCTGATAAGGTGGACGTCTTTGTGACCAAGTCCAAGATT
GACCAGAATTTGGATTTTGAAGATTTGGCGGATCTACCAGACATGGAAGAATTAGCCCAAATGTCGCCGGATGAATTTCT
CAAAACCTTGGAAAAGAGTATTGCAGATAAGACCAAGGACGATATTGAGGCCATCCAATCTCTAGAGCAGGTCGAAGCAA
AGGAAGAAGAGCAAGAGCAGGAAGACAAGGAGACTGAGAATAAGAAAGAACCTTATATCTACTATATCCTGCGCTTTTCA
AGCCTTGCTGACTTGGTTGCTTTTGCAAAGACGGTTAACTACCAGATGGAAACATCTGAACTCTATAAGATGAATGGGCA
CTACTATTTGACAATCTTAGTCGATGTGGAAAATCATCCAAGTCCATATCCGGCTTGGCTCTTGGCTCGTATGCGTGAGT
TTGCAGACGACAGTGACATCAGTCGTTCAGTCTTGCAAGAGTATGGGCAAATCTTGATCAATCACGATGCAGTTCTTAAT
CTGCAAAAGATTCGTTCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

90.164

99.187

0.894
  mecA Streptococcus pneumoniae D39

90.164

99.187

0.894
  mecA Streptococcus pneumoniae R6

90.164

99.187

0.894
  mecA Streptococcus pneumoniae TIGR4

89.754

99.187

0.89
  mecA Streptococcus thermophilus LMD-9

48.016

100

0.492
  mecA Streptococcus thermophilus LMG 18311

47.619

100

0.488
  mecA Streptococcus mutans UA159

48.361

99.187

0.48