Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   KW2_RS01960 Genome accession   NC_022369
Coordinates   395335..396762 (-) Length   475 a.a.
NCBI ID   WP_021036729.1    Uniprot ID   -
Organism   Lactococcus cremoris subsp. cremoris KW2     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 390335..401762
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KW2_RS01930 (kw2_0390) nox 390344..391684 (+) 1341 WP_011834457.1 H2O-forming NADH oxidase -
  KW2_RS01935 (kw2_0391) ssbB 391775..392164 (+) 390 WP_021036727.1 single-stranded DNA-binding protein Machinery gene
  KW2_RS01940 (kw2_0392) groES 392283..392567 (+) 285 WP_011834459.1 co-chaperone GroES -
  KW2_RS01945 (kw2_0393) groL 392654..394282 (+) 1629 WP_011675465.1 chaperonin GroEL -
  KW2_RS01950 (kw2_0394) vicX 394332..395144 (-) 813 WP_021036728.1 MBL fold metallo-hydrolase Regulator
  KW2_RS01960 (kw2_0395) vicK 395335..396762 (-) 1428 WP_021036729.1 sensor histidine kinase Regulator
  KW2_RS01965 (kw2_0396) yycF 396755..397456 (-) 702 WP_003131580.1 response regulator YycF -
  KW2_RS01970 (kw2_0397) tmk 397634..398269 (+) 636 WP_021036730.1 dTMP kinase -
  KW2_RS01975 (kw2_0398) - 398403..399263 (+) 861 WP_021036731.1 DNA polymerase III subunit delta' -
  KW2_RS01980 (kw2_0399) yaaT 399313..400095 (+) 783 WP_011834464.1 PSP1 domain-containing protein Regulator
  KW2_RS01985 (kw2_0400) yabA 400088..400414 (+) 327 WP_011675472.1 DNA replication initiation control protein YabA -
  KW2_RS01990 (kw2_0401) rsmI 400414..401289 (+) 876 WP_011834466.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  KW2_RS01995 (kw2_0402) - 401367..401558 (-) 192 WP_011675474.1 hypothetical protein -

Sequence

Protein


Download         Length: 475 a.a.        Molecular weight: 54127.70 Da        Isoelectric Point: 4.7356

>NTDB_id=51646 KW2_RS01960 WP_021036729.1 395335..396762(-) (vicK) [Lactococcus cremoris subsp. cremoris KW2]
MIKFFNSMIFKGVVAHLLLFVILFMSNFDYNLIHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYEEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTSNELLMEKNIVD
VLKIADQYNFYDLLEKEPEITIETHDAGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIDDKETASSFIGVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEIINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSDKPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVETRERDVLISIKDEGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEDKGTTFSFTLPYSSETSEYWDDAADDFE

Nucleotide


Download         Length: 1428 bp        

>NTDB_id=51646 KW2_RS01960 WP_021036729.1 395335..396762(-) (vicK) [Lactococcus cremoris subsp. cremoris KW2]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCCCACCTACTTCTTTTTGTCATTCTTTTCATGAGCAA
TTTCGATTATAATCTCATTCATCTTAGTACTTTTATTGGTTATTATTTATTTTCACTCGTTTTTGTTCTGGTTTTTCTCA
ATCAGCAACATCGAATGATTGTGAATGTTTCTAAACAAATGAACGATATAAAAAACGGTTATTTGAATAGAGATAAAATT
CCAAAAGGGACAAGTGAAATCAATGAATTATATGAAGAAATTTTGAAGCTTGGTGAGGACATTGTTCGGACTCAAAATAA
TCTTGAAAATCAACGCAATCAATTAGATAGCATTCTTGCCTACATGGTTGACGGAGTGATTGCCACAGATCGCCGTGGTA
ATATCATCATGGCTAATAAGTCAGCCCTCCATTACCTAAACACAAGTAATGAGCTTCTAATGGAAAAGAATATTGTTGAT
GTTTTGAAAATCGCAGACCAGTATAACTTTTATGATTTACTTGAAAAAGAACCTGAAATAACCATCGAAACACACGATGC
TGGGAATGAATCAATTTCACTCCACATCAAATTTGCACTCTTTCGTCGTGAGTCAGGGTTCATTTCAGGAATTATTGCTG
TCTTGCACGACATGACCGAACAAGATAAAGCAGAACGTGAACGTCGTCTTTTTGTTTCTAACGTCTCGCATGAATTAAGA
ACTCCTCTTACTTCCGTCAAGGCCTATCTTGAAGCATTAGAAGATGGCGCAATTGATGATAAAGAAACAGCCTCTTCATT
CATCGGTGTTTCACTAACCGAAACCAATCGAATGATTCGGATGATTTCTGATCTTTTAACATTGTCAAGAATGGACCAAG
ATCGAATTGTTCTTAATAAAGAAATCATTAATTTAATTGCCTTTTTAGACTATCAAATTAATCGATTAGACCAGATTTTA
GAAACTGAATCAAATGATTTAATTTCATCCAATTTTACACTCGTTAGAAAGTATTCTGACAAGCCAATCTGGGTAGAAAT
TGATACCGATAAAATCGCCCAAGTCATTGATAATATCATTGGTAATGCCATTAAATATTCACCAAAAGGTGGTACAATTA
CAATTTCCGTTGAAACTCGTGAACGAGATGTCTTAATTTCGATTAAAGACGAAGGAATGGGAATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTATCGAGTAGATAATGCTTCAAGAAATTCAAAAGTAGGTGGAACAGGTTTAGGCTTATC
TATTGTCCATGACATTGTCAAAATACATGGCGGAACAATTTTTGCAAGCTCCGAAGGCGAAGACAAAGGAACAACTTTCA
GTTTCACACTGCCATATTCTTCTGAAACTTCCGAATATTGGGATGACGCTGCTGATGATTTTGAATAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.905

88.421

0.459
  micB Streptococcus pneumoniae Cp1015

47.991

94.316

0.453