Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   I6H76_RS05810 Genome accession   NZ_CP065994
Coordinates   1117681..1118931 (-) Length   416 a.a.
NCBI ID   WP_006531186.1    Uniprot ID   A0A380KRK9
Organism   Streptococcus infantarius strain FDAARGOS_1019     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1112681..1123931
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H76_RS05785 (I6H76_05785) - 1112758..1112949 (-) 192 WP_006531193.1 DUF951 domain-containing protein -
  I6H76_RS05790 (I6H76_05790) - 1112960..1113844 (-) 885 Protein_1089 diacylglycerol/lipid kinase family protein -
  I6H76_RS05795 (I6H76_05795) dnaN 1113975..1115111 (-) 1137 WP_006531189.1 DNA polymerase III subunit beta -
  I6H76_RS05800 (I6H76_05800) dnaA 1115270..1116628 (-) 1359 WP_006531188.1 chromosomal replication initiator protein DnaA -
  I6H76_RS05805 (I6H76_05805) spo0J 1116832..1117614 (-) 783 WP_006531187.1 ParB/RepB/Spo0J family partition protein Regulator
  I6H76_RS05810 (I6H76_05810) htrA 1117681..1118931 (-) 1251 WP_006531186.1 S1C family serine protease Regulator
  I6H76_RS05815 (I6H76_05815) rlmH 1119146..1119625 (+) 480 WP_006531185.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6H76_RS05835 (I6H76_05835) - 1120486..1121837 (+) 1352 WP_115283723.1 IS3 family transposase -

Sequence

Protein


Download         Length: 416 a.a.        Molecular weight: 43339.49 Da        Isoelectric Point: 4.6661

>NTDB_id=516140 I6H76_RS05810 WP_006531186.1 1117681..1118931(-) (htrA) [Streptococcus infantarius strain FDAARGOS_1019]
MKKIKFQKVNYKKILKPLSVILVGFIGGVAGTLLILNMAGISINNVSSSSTKTTTSKVSYSNTNDTTKAVEKVREAVVSV
INYQSNSSSDDLYMQMFGGNLDNNTNNGSDSDLSIASEGSGVIYKKDGNSAYVVTNNHVVDGASQIEIMLSDGTKVVGEL
VGTDTYSDIAVVKIASDKVTTVAEFADSDKVTVGETAIAIGSPLGTDYANSVTQGIVSSLSRTVTMTNDDGDTISTNAIQ
TDAAINPGNSGGALINIEGQVIGINSSKISSTSDSGSGNSVEGMGFAIPANDVVKIINQLEANGKVIRPALGITMANLSD
LSTTTISRLNIPTSVTSGIVVASVQSGMPAEGTLKKYDVITAIDDKDVSSITDLQSVLYGHSTGDSIKVTFYRGTDKKTE
TIKLTKTTQDLSSSNQ

Nucleotide


Download         Length: 1251 bp        

>NTDB_id=516140 I6H76_RS05810 WP_006531186.1 1117681..1118931(-) (htrA) [Streptococcus infantarius strain FDAARGOS_1019]
GTGAAAAAAATAAAATTTCAAAAAGTCAATTACAAAAAAATCCTTAAACCACTATCCGTTATTTTAGTTGGTTTCATCGG
AGGAGTTGCTGGGACCTTACTCATTTTGAATATGGCTGGCATCTCAATCAATAATGTTAGTAGTTCAAGTACAAAAACTA
CAACAAGTAAAGTAAGTTACTCAAATACTAATGATACGACAAAAGCTGTCGAAAAAGTGAGAGAAGCAGTCGTATCAGTC
ATCAATTATCAATCAAATAGCTCTTCAGATGATTTGTATATGCAAATGTTTGGTGGAAATTTAGACAATAACACTAATAA
TGGATCAGATAGTGATTTAAGTATCGCTAGTGAAGGTTCTGGGGTTATTTACAAAAAAGACGGCAATTCTGCTTATGTTG
TTACTAATAACCACGTTGTCGATGGTGCTAGTCAAATCGAAATTATGCTTTCTGACGGTACAAAAGTAGTCGGTGAATTA
GTCGGTACCGATACATACTCAGATATCGCCGTTGTCAAAATTGCTTCTGATAAAGTCACAACGGTAGCTGAATTTGCTGA
TTCAGATAAAGTTACTGTTGGTGAAACAGCCATCGCTATTGGTAGCCCTCTAGGTACTGATTATGCTAACTCTGTGACAC
AAGGAATTGTCTCAAGTCTAAGCCGTACAGTTACAATGACTAACGACGATGGCGACACAATTTCAACCAATGCTATCCAA
ACTGATGCCGCTATTAACCCAGGTAACTCTGGTGGTGCTTTGATTAACATTGAAGGACAAGTAATCGGTATTAATTCAAG
TAAAATCTCTTCTACCTCAGATTCTGGATCAGGTAATTCTGTAGAAGGTATGGGATTTGCTATTCCAGCTAATGATGTGG
TTAAAATTATTAATCAATTAGAAGCAAACGGAAAAGTTATTCGTCCAGCACTTGGTATCACAATGGCTAACCTAAGCGAT
TTATCAACAACAACAATCAGTCGACTAAATATTCCAACTAGCGTCACATCTGGTATCGTCGTTGCTTCAGTTCAATCAGG
TATGCCTGCTGAAGGAACACTTAAAAAATACGATGTAATCACAGCTATCGATGATAAAGATGTCTCTTCTATCACAGATC
TTCAAAGTGTTCTTTACGGTCATTCAACTGGAGATTCTATTAAAGTAACCTTCTATCGTGGTACTGACAAGAAAACAGAA
ACTATTAAATTAACGAAAACAACACAAGACCTCTCTTCATCAAATCAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(119-264)

PDZ domain (PDZ_2)

(309-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380KRK9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

64.339

96.394

0.62
  htrA Streptococcus gordonii str. Challis substr. CH1

61.235

97.356

0.596
  htrA Streptococcus mitis NCTC 12261

59.124

98.798

0.584
  htrA Streptococcus pneumoniae TIGR4

58.881

98.798

0.582
  htrA Streptococcus pneumoniae D39

58.881

98.798

0.582
  htrA Streptococcus pneumoniae Rx1

58.881

98.798

0.582
  htrA Streptococcus pneumoniae R6

58.881

98.798

0.582