Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   I6H76_RS04080 Genome accession   NZ_CP065994
Coordinates   810303..811016 (-) Length   237 a.a.
NCBI ID   WP_006530958.1    Uniprot ID   A0A380KMR6
Organism   Streptococcus infantarius strain FDAARGOS_1019     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 805303..816016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H76_RS04060 (I6H76_04060) - 805683..806915 (-) 1233 WP_006530954.1 cysteine desulfurase -
  I6H76_RS04065 (I6H76_04065) sufD 806917..808179 (-) 1263 WP_014334313.1 Fe-S cluster assembly protein SufD -
  I6H76_RS04070 (I6H76_04070) sufC 808254..809024 (-) 771 WP_006530956.1 Fe-S cluster assembly ATPase SufC -
  I6H76_RS04075 (I6H76_04075) - 809138..810301 (-) 1164 WP_006530957.1 glycosyltransferase family 4 protein -
  I6H76_RS04080 (I6H76_04080) mecA 810303..811016 (-) 714 WP_006530958.1 adaptor protein MecA Regulator
  I6H76_RS04085 (I6H76_04085) - 811120..811959 (-) 840 WP_006530959.1 undecaprenyl-diphosphate phosphatase -
  I6H76_RS04090 (I6H76_04090) - 812011..813903 (-) 1893 WP_174221226.1 DUF2207 domain-containing protein -
  I6H76_RS04095 (I6H76_04095) - 814040..815611 (+) 1572 WP_006530981.1 ABC transporter permease subunit -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27282.96 Da        Isoelectric Point: 4.0947

>NTDB_id=516124 I6H76_RS04080 WP_006530958.1 810303..811016(-) (mecA) [Streptococcus infantarius strain FDAARGOS_1019]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRIDVFVTKSEI
NKDINFEDLAAFDDVSNMSPEEFFKTLEQTMLSKGDTEAHEKLGKIEEMMEGAVEDVNPSDYVHYVLDFPSLEATVAFAK
AIDFPVEASELYKMDGAYYMTVLIDLQNHPSYYANLMYARMLEYAGAGTKTRAYLQEHAVELLTDDAVEKLKMIELV

Nucleotide


Download         Length: 714 bp        

>NTDB_id=516124 I6H76_RS04080 WP_006530958.1 810303..811016(-) (mecA) [Streptococcus infantarius strain FDAARGOS_1019]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATTTAGAAGAACGCGGAATGGAGTT
GAAAGACTTCTTGATTCCACAAGAAAAGACAGAAGAGTTCTTCTATTCAGTAATGGATGAATTGGATTTACCAGATAATT
TCAAAGACAGTGGCATGCTTAGTTTCCGTGTGACACCACGTAAAGACCGCATTGATGTCTTTGTTACCAAATCTGAAATC
AATAAAGATATAAACTTTGAAGATCTAGCAGCCTTTGATGATGTTTCAAACATGTCACCTGAGGAATTTTTCAAGACTTT
AGAGCAGACAATGTTGTCTAAAGGCGACACGGAAGCTCACGAAAAATTAGGTAAGATTGAAGAAATGATGGAAGGTGCTG
TTGAAGATGTGAATCCATCAGATTATGTTCACTATGTCTTGGATTTTCCAAGCTTAGAAGCTACTGTTGCTTTTGCTAAG
GCTATTGATTTTCCAGTTGAAGCTTCAGAGCTTTATAAGATGGATGGGGCTTACTACATGACAGTTCTCATTGATTTGCA
AAATCACCCATCTTATTATGCAAATTTGATGTATGCTCGTATGTTAGAATACGCTGGCGCTGGTACAAAAACTCGTGCTT
ATTTACAAGAGCATGCGGTTGAATTATTGACGGATGATGCCGTCGAAAAATTAAAAATGATTGAGTTGGTATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380KMR6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

69.038

100

0.696
  mecA Streptococcus thermophilus LMD-9

59.016

100

0.608
  mecA Streptococcus thermophilus LMG 18311

58.197

100

0.599
  mecA Streptococcus pneumoniae Rx1

50.41

100

0.519
  mecA Streptococcus pneumoniae D39

50.41

100

0.519
  mecA Streptococcus pneumoniae R6

50.41

100

0.519
  mecA Streptococcus pneumoniae TIGR4

50.41

100

0.519