Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   I6H76_RS03510 Genome accession   NZ_CP065994
Coordinates   697237..699126 (-) Length   629 a.a.
NCBI ID   WP_006531174.1    Uniprot ID   -
Organism   Streptococcus infantarius strain FDAARGOS_1019     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 692237..704126
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H76_RS03485 (I6H76_03485) - 692914..693270 (-) 357 WP_006531179.1 S1 RNA-binding domain-containing protein -
  I6H76_RS03490 (I6H76_03490) - 693270..694670 (-) 1401 WP_081442254.1 Cof-type HAD-IIB family hydrolase -
  I6H76_RS03495 (I6H76_03495) - 694794..695438 (-) 645 WP_006531177.1 response regulator transcription factor -
  I6H76_RS03500 (I6H76_03500) - 695422..696447 (-) 1026 WP_006531176.1 sensor histidine kinase -
  I6H76_RS03505 (I6H76_03505) liaF 696444..697139 (-) 696 WP_006531175.1 cell wall-active antibiotics response protein LiaF -
  I6H76_RS03510 (I6H76_03510) stkP/pknB 697237..699126 (-) 1890 WP_006531174.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  I6H76_RS03515 (I6H76_03515) - 699126..699863 (-) 738 WP_043878264.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  I6H76_RS03520 (I6H76_03520) rsmB 699901..701223 (-) 1323 WP_006531172.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  I6H76_RS03525 (I6H76_03525) fmt 701213..702148 (-) 936 WP_006531171.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 629 a.a.        Molecular weight: 68493.54 Da        Isoelectric Point: 7.6405

>NTDB_id=516118 I6H76_RS03510 WP_006531174.1 697237..699126(-) (stkP/pknB) [Streptococcus infantarius strain FDAARGOS_1019]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSRERKLVFEDTENTKTLPKVTTSTPVPSTKEQLLKKQKAAKVN
REAADNKIAKAKTKKKKSHRMFGTLVKIFFAVVVVAIAIFTYLTLSTPASVNVPNVAGTSLQAAKTSLTSAGLKVGKTRK
IYSDTVPSGQVIETNPKAGTSKKEGAKVDIYVSKGTSGFKMKDYTGQNYQEVIKELKDKHGISSDKIDVEWITGTNYDGG
TIISQTPEKGTKVVSEDKITFKVAAYVMPNLIGYTYQDAIAELTALGLSSSHITVFQADATSSTGYSQVKTPSASAVVVE
QYPYFGAAIEGNVKLFFSAGSESQSSEVAPSQSVPESSETSETSESSSSSSSSSSTEESSQTDSSSVEQ

Nucleotide


Download         Length: 1890 bp        

>NTDB_id=516118 I6H76_RS03510 WP_006531174.1 697237..699126(-) (stkP/pknB) [Streptococcus infantarius strain FDAARGOS_1019]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTCAAATCTATCGGACGGGGTGGAATGGCAGATGTTTA
TCTTGCCAAAGATTTGATTCTTGATAATGAAGAAGTGGCAATCAAGGTCCTTCGGACGAATTATCAAACAGATCAAATTG
CCGTTGCTCGTTTCCAACGTGAAGCGCGTGCCATGGCAGAGCTGAACCATCCAAATATTGTTTCGATTCGTGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGCTCGGACTTGAAGAAATACATTCAAGACCATGCCCC
TCTTTCTAATAATGAAGTTGTTAGAATCATGGAAGAAGTCTTGTCTGCGATGACTTTGGCTCATCAACAAGGAATTGTTC
ACCGTGATTTGAAACCACAAAATATCTTGTTAACCAAAGACGGAACGGTTAAAGTTACCGACTTTGGTATCGCTGTAGCT
TTTGCAGAAACAAGTTTAACACAGACAAACTCAATGCTTGGTAGTGTACACTATTTATCACCTGAACAAGCGCGTGGATC
AAAAGCCACTGTTCAAAGTGATATCTACGCTATGGGGATTATGTTGTTTGAAATGTTGACTGGTCACATCCCATATGATG
GTGATTCAGCTGTTACAATTGCTCTTCAACATTTCCAAAAACCACTTCCATCAATCATTGATGAAAATAAAAATGTTCCA
CAAGCTTTGGAAAATGTTGTCATTAAAGCAACTGCAAAACGTCTGAGTGATCGCTACGCCTCAACTTTTGAGATGAGCCG
TGATTTAATGACTGCTCTTTCATATAACCGCAGTCGTGAACGCAAACTTGTCTTTGAAGATACAGAAAATACGAAGACAC
TTCCAAAAGTAACAACTTCAACACCTGTTCCCTCAACTAAAGAACAATTGTTGAAAAAACAAAAAGCGGCTAAAGTTAAT
CGTGAAGCTGCGGATAATAAAATTGCAAAAGCGAAAACGAAGAAGAAAAAATCACATCGTATGTTTGGTACTTTAGTGAA
AATTTTCTTTGCGGTCGTAGTAGTTGCAATTGCTATCTTTACTTACTTGACGCTAAGCACACCAGCTTCAGTCAACGTTC
CAAATGTAGCTGGAACAAGTTTACAAGCTGCTAAGACAAGTCTTACATCAGCAGGGCTTAAAGTTGGAAAGACCAGGAAA
ATTTATAGTGACACTGTTCCAAGTGGTCAGGTTATTGAGACTAATCCGAAAGCTGGCACATCTAAGAAAGAAGGTGCCAA
AGTTGATATTTATGTATCAAAAGGAACTTCAGGCTTCAAGATGAAAGATTATACTGGTCAAAACTATCAGGAAGTTATCA
AAGAACTCAAAGATAAGCACGGTATTTCAAGTGATAAGATTGATGTTGAATGGATAACAGGTACTAACTATGACGGTGGT
ACTATCATTAGTCAAACACCTGAAAAAGGTACAAAAGTAGTTAGTGAAGATAAGATTACTTTCAAGGTTGCAGCTTATGT
GATGCCGAACTTAATTGGTTATACTTATCAAGATGCAATTGCTGAATTGACTGCACTTGGCTTATCAAGCTCACATATTA
CAGTATTCCAAGCTGATGCTACTTCATCAACTGGATACTCTCAAGTCAAAACACCATCTGCTTCTGCAGTTGTTGTGGAA
CAATATCCTTATTTCGGTGCAGCTATTGAAGGAAATGTGAAACTTTTCTTCTCAGCTGGAAGTGAATCTCAGTCTTCAGA
AGTCGCACCATCTCAATCTGTTCCTGAGTCATCTGAGACAAGTGAAACTAGTGAGTCAAGTTCTTCAAGTAGCAGCAGTA
GCAGCACTGAAGAAAGTTCACAAACCGACTCATCATCAGTTGAACAATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-247)

PASTA domain (PASTA)

(440-503)

PASTA domain (PASTA)

(507-575)

PASTA domain (PASTA)

(371-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

60.224

99.523

0.599
  pknB Streptococcus mutans UA159

65.674

90.779

0.596
  stkP Streptococcus pneumoniae TIGR4

58.192

84.42

0.491
  stkP Streptococcus pneumoniae D39

58.004

84.42

0.49
  stkP Streptococcus pneumoniae R6

58.004

84.42

0.49
  stkP Streptococcus pneumoniae Rx1

57.815

84.42

0.488