Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   I6H60_RS00630 Genome accession   NZ_CP065993
Coordinates   122055..123188 (+) Length   377 a.a.
NCBI ID   WP_010295968.1    Uniprot ID   -
Organism   Leuconostoc pseudomesenteroides strain FDAARGOS_1003     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 117055..128188
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H60_RS00610 (I6H60_00610) yycF 117171..117878 (+) 708 WP_004911084.1 response regulator YycF -
  I6H60_RS00615 (I6H60_00615) walK 117943..119808 (+) 1866 WP_010295976.1 cell wall metabolism sensor histidine kinase WalK -
  I6H60_RS00620 (I6H60_00620) - 119798..121096 (+) 1299 WP_010295972.1 hypothetical protein -
  I6H60_RS00625 (I6H60_00625) yycI 121260..121991 (+) 732 WP_010295970.1 two-component system regulatory protein YycI -
  I6H60_RS00630 (I6H60_00630) htrA 122055..123188 (+) 1134 WP_010295968.1 trypsin-like peptidase domain-containing protein Regulator
  I6H60_RS00635 (I6H60_00635) rlmH 123818..124297 (+) 480 WP_010295966.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6H60_RS00640 (I6H60_00640) - 124337..125020 (-) 684 WP_031941381.1 NAD(P)H-hydrate epimerase -
  I6H60_RS00645 (I6H60_00645) - 125079..125900 (-) 822 WP_010295962.1 serine hydrolase -
  I6H60_RS00650 (I6H60_00650) alr 126293..127405 (+) 1113 WP_010295960.1 alanine racemase -

Sequence

Protein


Download         Length: 377 a.a.        Molecular weight: 39133.44 Da        Isoelectric Point: 9.6575

>NTDB_id=516082 I6H60_RS00630 WP_010295968.1 122055..123188(+) (htrA) [Leuconostoc pseudomesenteroides strain FDAARGOS_1003]
MAQSTLTKTVLTGVIAGLVGGGVILYAQKGIEQSTTQTTVRTTATKTSSIAKNATATTAYNKVSDAVVSVLNFSKSGQNY
EESSEGSGVIYKKADQSAFIVTNNHVIDGAAKIQVMLHNGKKVDATLVGKDAMTDLAVLKIASDNVTTTAEFGDSSKIAV
GENVLAIGSPLGSEYASSVTQGIISAKKRLVEATSENGQNYGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLSTS
SSGTSVEGMGFAIPSDQVVDVVNKLVKDGKITRPAIGIGLVNLSEVTADDQKSTLKIPDSVTGGVVVMSLTKKGPADTAG
LKKYDVIVGIDGKKVTTQADLREELYKHKLGDTVTLTYYHHSNKKTVKVKLTQKLAS

Nucleotide


Download         Length: 1134 bp        

>NTDB_id=516082 I6H60_RS00630 WP_010295968.1 122055..123188(+) (htrA) [Leuconostoc pseudomesenteroides strain FDAARGOS_1003]
ATGGCACAATCAACATTAACAAAAACAGTGTTAACTGGCGTCATTGCAGGGCTAGTTGGCGGAGGCGTTATTTTATACGC
ACAAAAAGGAATCGAACAGAGTACCACACAAACGACAGTGCGTACAACGGCAACCAAAACGTCGTCAATTGCGAAAAATG
CCACTGCCACAACAGCGTATAATAAAGTTTCAGATGCGGTTGTGTCTGTATTGAATTTTAGTAAATCGGGACAAAATTAT
GAAGAATCATCTGAAGGTTCTGGTGTCATTTACAAAAAAGCAGATCAATCAGCGTTTATTGTAACAAATAATCATGTCAT
TGATGGTGCAGCTAAAATTCAAGTAATGCTCCACAATGGTAAAAAAGTGGATGCTACCTTGGTTGGTAAAGATGCTATGA
CTGACTTAGCGGTTCTAAAGATTGCGAGTGACAATGTGACAACAACTGCTGAGTTTGGTGATTCTAGTAAAATAGCGGTT
GGAGAAAATGTGTTAGCGATTGGCTCTCCTCTAGGATCAGAATATGCCTCTTCGGTTACGCAAGGCATAATTTCAGCTAA
AAAACGATTAGTCGAAGCCACTTCTGAAAATGGTCAAAATTATGGTGGTTCAACTGTTATTCAAACAGATGCCGCGATTA
ATCCGGGCAATTCCGGTGGGCCTTTAATTAATTTTGCTGGTCAAGTTATTGGAATTAATTCAATGAAGTTATCTACTTCG
TCATCAGGTACAAGTGTTGAGGGAATGGGATTTGCTATTCCCTCAGATCAAGTGGTAGACGTTGTCAATAAGTTGGTTAA
GGATGGGAAGATTACGCGGCCGGCCATTGGCATTGGTTTAGTTAATTTGTCAGAAGTGACTGCTGACGATCAAAAGTCTA
CACTCAAAATTCCTGATAGTGTCACTGGTGGTGTGGTTGTTATGAGTTTGACGAAAAAAGGACCGGCTGATACTGCTGGG
TTGAAGAAGTATGATGTAATTGTGGGTATTGATGGCAAGAAAGTGACAACACAAGCTGACCTACGTGAAGAGCTGTATAA
ACATAAATTAGGTGATACGGTTACACTGACATATTACCACCACAGTAATAAGAAAACAGTTAAAGTTAAATTAACTCAAA
AATTAGCAAGCTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(86-232)

PDZ domain (PDZ_2)

(274-371)

Peptidase family M50 (Peptidase_M50)

(185-373)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

49.067

99.469

0.488
  htrA Streptococcus pneumoniae Rx1

52.187

90.981

0.475
  htrA Streptococcus pneumoniae D39

52.187

90.981

0.475
  htrA Streptococcus pneumoniae R6

52.187

90.981

0.475
  htrA Streptococcus pneumoniae TIGR4

52.187

90.981

0.475
  htrA Streptococcus mutans UA159

52.647

90.186

0.475
  htrA Streptococcus gordonii str. Challis substr. CH1

45.91

100

0.462