Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   KX728_RS03685 Genome accession   NZ_CP079724
Coordinates   735995..736735 (+) Length   246 a.a.
NCBI ID   WP_215804968.1    Uniprot ID   -
Organism   Streptococcus oralis strain 34     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 730995..741735
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KX728_RS03675 (KX728_03670) - 731819..734347 (+) 2529 WP_215804781.1 MBL fold metallo-hydrolase -
  KX728_RS03680 (KX728_03675) - 734394..735872 (-) 1479 WP_215804780.1 oligosaccharide flippase family protein -
  KX728_RS03685 (KX728_03680) mecA 735995..736735 (+) 741 WP_215804968.1 adaptor protein MecA Regulator
  KX728_RS03690 (KX728_03685) - 736883..738169 (+) 1287 WP_215804779.1 homoserine dehydrogenase -
  KX728_RS03695 (KX728_03690) thrB 738171..739040 (+) 870 WP_215804778.1 homoserine kinase -
  KX728_RS03700 (KX728_03695) msrB 739300..740238 (+) 939 WP_215804777.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28484.30 Da        Isoelectric Point: 4.1097

>NTDB_id=514611 KX728_RS03685 WP_215804968.1 735995..736735(+) (mecA) [Streptococcus oralis strain 34]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQTLDFEDLADLPDMEELAQMSPDEFLKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQADKETESKKEPYIYYILRFA
SLADLVAFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVLG
LQKIRS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=514611 KX728_RS03685 WP_215804968.1 735995..736735(+) (mecA) [Streptococcus oralis strain 34]
ATGAAGATGAAACAAATTAGTGATACAACACTGAAAATCACGATGACTTTAGATGATTTGATGGATAGAGGAATGGAGAT
TGCAGACTTTCTCGTTCCTCAGGAAAAAACCGAAGAGTTTTTCTATGCTATTTTAGATGAGTTAGAGATGCCAGACAATT
TCTTGGATAGTGGTATGCTGAGTTTCCGCGTGACGCCAAAACCTGATAAGGTGGACGTCTTTGTGACCAAATCCAAGATT
GACCAAACTCTGGATTTTGAAGATTTGGCGGATCTACCAGACATGGAAGAATTAGCCCAAATGTCGCCAGATGAATTTCT
CAAAACCTTGGAAAAGAGTATTGCAGATAAAACCAAGGACGATATTGAGGCCATCCAATCTCTAGAGCAGGTCGAAGCAA
AGGAAGAAGAGCAAGAGCAGGCAGACAAGGAGACTGAGAGTAAGAAAGAACCTTATATCTACTATATCCTGCGCTTTGCA
AGCCTTGCTGACTTAGTTGCTTTTGCAAAGACGGTTAACTACCAGATGGAAACATCTGAACTCTATAAGATGAATGGACA
CTATTATTTGACAATCTTAGTCGATGTGGAAAATCATCCAAGTCCATATCCGGCTTGGCTCTTGGCTCGTATGCGTGAGT
TTGCAGACGACAGTGACATCAGTCGTTCAGTCTTGCAAGAGTATGGGCAAATATTGATTAACCATGACGCAGTTCTCGGT
CTGCAAAAGATTCGTTCATAA

Domains

Predicted by InterProScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

90.574

99.187

0.898
  mecA Streptococcus pneumoniae D39

90.574

99.187

0.898
  mecA Streptococcus pneumoniae R6

90.574

99.187

0.898
  mecA Streptococcus pneumoniae TIGR4

90.164

99.187

0.894
  mecA Streptococcus thermophilus LMD-9

47.222

100

0.484
  mecA Streptococcus thermophilus LMG 18311

47.222

100

0.484
  mecA Streptococcus mutans UA159

47.951

99.187

0.476