Detailed information NTG0514285

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: STMM8_RS08505
• Genome accession: NZ_CP065787
• Coordinates: 1633431..1633868 (-)
• Length: 145 a.a.
• NCBI ID: WP_022096897.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain MM8
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1628431..1638868

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STMM8_RS08470 (STMM8_08435)	-	1628491..1629152 (-)	662	Protein_1610	CPBP family intramembrane glutamic endopeptidase	-
STMM8_RS08475 (STMM8_08440)	-	1629255..1629698 (-)	444	WP_002946118.1	hypothetical protein	-
STMM8_RS08480	-	1629772..1630197 (-)	426	WP_014608739.1	CPBP family intramembrane glutamic endopeptidase	-
STMM8_RS08485 (STMM8_08450)	-	1630440..1630637 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
STMM8_RS08490 (STMM8_08455)	-	1630886..1632079 (-)	1194	WP_022096898.1	acetate kinase	-
STMM8_RS08495 (STMM8_08460)	comYH	1632135..1633091 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
STMM8_RS08500 (STMM8_08465)	comGG	1633136..1633453 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
STMM8_RS08505 (STMM8_08470)	comYF	1633431..1633868 (-)	438	WP_022096897.1	competence type IV pilus minor pilin ComGF	Machinery gene
STMM8_RS08510 (STMM8_08475)	comGE	1633852..1634145 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
STMM8_RS08515 (STMM8_08480)	comYD	1634117..1634545 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
STMM8_RS08520 (STMM8_08485)	comYC	1634505..1634831 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
STMM8_RS08525 (STMM8_08490)	comYB	1634828..1635928 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
STMM8_RS08530 (STMM8_08495)	comGA/cglA/cilD	1635810..1636751 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
STMM8_RS08535 (STMM8_08500)	-	1636832..1637194 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16375.89 Da
• Isoelectric Point: 8.9784

>NTDB_id=514285 STMM8_RS08505 WP_022096897.1 1633431..1633868(-) (comYF) [Streptococcus thermophilus strain MM8]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=514285 STMM8_RS08505 WP_022096897.1 1633431..1633868(-) (comYF) [Streptococcus thermophilus strain MM8]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae Rx1	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae R6	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae TIGR4	48.571	96.552	0.469
comGF/cglF	Streptococcus mitis NCTC 12261	46.809	97.241	0.455
comGF/cglF	Streptococcus mitis SK321	46.099	97.241	0.448
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441