Detailed information NTG0514288

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: STMM8_RS08525
• Genome accession: NZ_CP065787
• Coordinates: 1634828..1635928 (-)
• Length: 366 a.a.
• NCBI ID: WP_116920398.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain MM8
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1629828..1640928

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STMM8_RS08485 (STMM8_08450)	-	1630440..1630637 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
STMM8_RS08490 (STMM8_08455)	-	1630886..1632079 (-)	1194	WP_022096898.1	acetate kinase	-
STMM8_RS08495 (STMM8_08460)	comYH	1632135..1633091 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
STMM8_RS08500 (STMM8_08465)	comGG	1633136..1633453 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
STMM8_RS08505 (STMM8_08470)	comYF	1633431..1633868 (-)	438	WP_022096897.1	competence type IV pilus minor pilin ComGF	Machinery gene
STMM8_RS08510 (STMM8_08475)	comGE	1633852..1634145 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
STMM8_RS08515 (STMM8_08480)	comYD	1634117..1634545 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
STMM8_RS08520 (STMM8_08485)	comYC	1634505..1634831 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
STMM8_RS08525 (STMM8_08490)	comYB	1634828..1635928 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
STMM8_RS08530 (STMM8_08495)	comGA/cglA/cilD	1635810..1636751 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
STMM8_RS08535 (STMM8_08500)	-	1636832..1637194 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41797.91 Da
• Isoelectric Point: 10.1084

>NTDB_id=514288 STMM8_RS08525 WP_116920398.1 1634828..1635928(-) (comYB) [Streptococcus thermophilus strain MM8]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=514288 STMM8_RS08525 WP_116920398.1 1634828..1635928(-) (comYB) [Streptococcus thermophilus strain MM8]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTAAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.695	89.617	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413