Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   STMM8_RS01015 Genome accession   NZ_CP065787
Coordinates   171667..172416 (+) Length   249 a.a.
NCBI ID   WP_022096529.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain MM8     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 166667..177416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STMM8_RS00985 (STMM8_00975) - 167241..167411 (+) 171 WP_011680664.1 hypothetical protein -
  STMM8_RS00990 (STMM8_00980) - 167498..167605 (+) 108 WP_084829946.1 LPXTG cell wall anchor domain-containing protein -
  STMM8_RS00995 (STMM8_00985) - 167693..168433 (-) 741 WP_002949253.1 amino acid ABC transporter ATP-binding protein -
  STMM8_RS01000 (STMM8_00990) - 168433..169983 (-) 1551 WP_022096528.1 ABC transporter substrate-binding protein/permease -
  STMM8_RS01005 (STMM8_00995) - 170186..171040 (+) 855 WP_014607892.1 undecaprenyl-diphosphate phosphatase -
  STMM8_RS01010 (STMM8_01000) - 171186..171401 (-) 216 WP_011226805.1 DUF3021 family protein -
  STMM8_RS01015 (STMM8_01005) mecA 171667..172416 (+) 750 WP_022096529.1 adaptor protein MecA Regulator
  STMM8_RS01020 (STMM8_01010) - 172420..173577 (+) 1158 WP_002947632.1 glycosyltransferase family 4 protein -
  STMM8_RS01025 (STMM8_01015) sufC 173738..174508 (+) 771 WP_002947634.1 Fe-S cluster assembly ATPase SufC -
  STMM8_RS01030 (STMM8_01020) sufD 174545..175807 (+) 1263 WP_002947640.1 Fe-S cluster assembly protein SufD -
  STMM8_RS01035 (STMM8_01025) - 175861..177093 (+) 1233 WP_022096530.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29156.76 Da        Isoelectric Point: 4.1121

>NTDB_id=514240 STMM8_RS01015 WP_022096529.1 171667..172416(+) (mecA) [Streptococcus thermophilus strain MM8]
MEMKQINETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEALDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKKVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSEFYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=514240 STMM8_RS01015 WP_022096529.1 171667..172416(+) (mecA) [Streptococcus thermophilus strain MM8]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAATT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGCCCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGAGCCGGCTAAGAAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAATTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMG 18311

99.598

100

0.996
  mecA Streptococcus thermophilus LMD-9

98.795

100

0.988
  mecA Streptococcus mutans UA159

57.787

97.992

0.566
  mecA Streptococcus pneumoniae Rx1

46.586

100

0.466
  mecA Streptococcus pneumoniae D39

46.586

100

0.466
  mecA Streptococcus pneumoniae R6

46.586

100

0.466
  mecA Streptococcus pneumoniae TIGR4

46.586

100

0.466