Detailed information NTG0513728

Bioinformatically predicted

Overview

• Name: pilU
• Type: Machinery gene
• Locus tag: KWY95_RS01845
• Genome accession: NZ_CP078117
• Coordinates: 344540..345766 (-)
• Length: 408 a.a.
• NCBI ID: WP_003690199.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain SK92679
• Function: mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 339540..350766

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KWY95_RS01830 (KWY95_01830)	-	340276..340560 (+)	285	WP_003701816.1	GIY-YIG nuclease family protein	-
KWY95_RS01835 (KWY95_01835)	-	341256..341540 (+)	285	WP_003701816.1	GIY-YIG nuclease family protein	-
KWY95_RS01840 (KWY95_01840)	yccS	342273..344423 (-)	2151	WP_003690198.1	YccS family putative transporter	-
KWY95_RS01845 (KWY95_01845)	pilU	344540..345766 (-)	1227	WP_003690199.1	PilT/PilU family type 4a pilus ATPase	Machinery gene
KWY95_RS01850 (KWY95_01850)	pilT	345930..346973 (-)	1044	WP_003690200.1	type IV pilus twitching motility protein PilT	Machinery gene
KWY95_RS01855 (KWY95_01855)	-	347093..347779 (+)	687	WP_003699139.1	YggS family pyridoxal phosphate-dependent enzyme	-
KWY95_RS01860 (KWY95_01860)	-	347779..348186 (+)	408	WP_003701818.1	hypothetical protein	-
KWY95_RS01865 (KWY95_01865)	proC	348217..349026 (+)	810	WP_228547131.1	pyrroline-5-carboxylate reductase	-
KWY95_RS01870 (KWY95_01870)	dksA	349175..349591 (+)	417	WP_003692108.1	RNA polymerase-binding protein DksA	-

Sequence

Protein

• Length: 408 a.a.
• Molecular weight: 45672.29 Da
• Isoelectric Point: 7.3203

>NTDB_id=513728 KWY95_RS01845 WP_003690199.1 344540..345766(-) (pilU) [Neisseria gonorrhoeae strain SK92679]
MNTDNLHDILDETVQVYSQKKQSRSETPAEIGTHFHPLLDRLCETAEAQNASDILISKGFPPSLKINSALTPQPQKALTG
EETAAIAASTMNAEQSEIFRRDGEINYSVQSRSGTRYRANAYHSQGSAGLVLRRINHVIPQMRELGLPEKLKDLAVAPRG
LLIIVGPTGSGKSTTMATMLEHRNKTLPGHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSPDVVCIGE
VRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKKDKTGRTAVVDLL
INTPAIQDFILKGDLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDR
VNGLNLIS

Nucleotide

• Length: 1227 bp

>NTDB_id=513728 KWY95_RS01845 WP_003690199.1 344540..345766(-) (pilU) [Neisseria gonorrhoeae strain SK92679]
ATGAATACCGATAACCTGCACGACATCTTGGACGAAACGGTTCAAGTGTATTCTCAAAAAAAACAAAGCCGATCCGAAAC
CCCGGCCGAAATCGGCACACACTTCCACCCGCTGCTCGACCGCCTGTGCGAAACCGCAGAAGCACAAAACGCGTCCGACA
TCCTTATCAGCAAAGGATTCCCGCCCTCGTTGAAAATCAACAGCGCATTAACCCCGCAGCCGCAAAAGGCTCTGACGGGC
GAGGAAACCGCCGCCATCGCCGCATCGACGATGAACGCCGAACAATCGGAAATATTCCGGCGCGACGGCGAAATCAACTA
CTCCGTCCAATCGCGCAGCGGCACGCGCTACCGCGCCAACGCCTACCACAGCCAAGGCAGCGCAGGTTTGGTTTTGCGGC
GCATCAACCACGTCATCCCGCAAATGCGGGAATTGGGCTTGCCCGAAAAACTCAAAGACCTCGCCGTCGCACCGCGCGGG
CTGCTGATTATCGTCGGGCCTACCGGTTCGGGCAAATCCACCACGATGGCGACTATGCTCGAACACCGCAACAAAACCCT
GCCCGGCCATATCGTTACCATCGAAGACCCGATTGAGTTTATCTACAAACCGCGCCGCTGCATCTTTACCCAGCGCGAAA
TCGGCGTCGACACCATAAACTGGCAGACGGCGGTACAAAACGCTATGCGCCAATCCCCAGACGTGGTCTGTATCGGCGAA
GTCCGCAGCAGGGAAAGTATGGAATACGCGATGCAGCTCGCCCAAACCGGCCACCTGTGCATTTTTACGCTCCACGCCAA
CACCGCGCCGCAGTCGCTCGAACGCATACTCAACTTCTACCCCAAAGAACAGCACAACCAAATACTGATTGACATCGCCC
TCAATCTGACCGGCATCATCTGCCAACGCCTCGCCCTCAAAAAAGACAAAACGGGCAGGACGGCGGTTGTCGACTTGCTC
ATCAACACGCCCGCCATCCAAGACTTCATCCTGAAGGGCGACCTGATGAACATCAGTAAAATCATGGAAACCGCCAAAAC
CGACGGAATGCAGACGATGGACCAAAACCTTTTCGAACTGTACCGTCACGGCATCATCAGTTACGAAGAAGCCCTGCGCC
AGTCCGTTTCCGCCAACAACCTGCGATTGCACATCCAACTGCACAAAGAAGGCAAAACGCCCGAACTCCTTTACGACAGG
GTCAACGGTCTCAACCTCATTTCCTGA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (49-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilU	Acinetobacter baylyi ADP1	44.875	88.48	0.397
pilU	Pseudomonas stutzeri DSM 10701	44.944	87.255	0.392
pilU	Vibrio cholerae strain A1552	47.024	82.353	0.387