Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   I6G22_RS05830 Genome accession   NZ_CP065737
Coordinates   1093070..1094575 (-) Length   501 a.a.
NCBI ID   WP_269670455.1    Uniprot ID   A0A0B8QXL5
Organism   Lactococcus lactis strain FDAARGOS_865     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1088070..1099575
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G22_RS05800 (I6G22_05805) - 1089605..1089757 (+) 153 WP_010905099.1 hypothetical protein -
  I6G22_RS05805 (I6G22_05810) - 1089767..1090048 (+) 282 WP_010905098.1 hypothetical protein -
  I6G22_RS05810 (I6G22_05815) - 1090151..1090807 (-) 657 WP_021214956.1 CPBP family intramembrane glutamic endopeptidase -
  I6G22_RS05815 (I6G22_05820) - 1090846..1091214 (-) 369 WP_223848592.1 transporter -
  I6G22_RS05820 (I6G22_05825) - 1091540..1091665 (-) 126 WP_021214955.1 lactococcin family bacteriocin -
  I6G22_RS13110 - 1091760..1092260 (-) 501 WP_223848591.1 HlyD family efflux transporter periplasmic adaptor subunit -
  I6G22_RS13115 - 1092555..1093043 (-) 489 WP_230494238.1 hypothetical protein -
  I6G22_RS05830 (I6G22_05835) comA 1093070..1094575 (-) 1506 WP_269670455.1 peptide cleavage/export ABC transporter Regulator
  I6G22_RS05835 (I6G22_05840) - 1095171..1095761 (-) 591 WP_023189481.1 flavin reductase family protein -
  I6G22_RS05840 (I6G22_05845) - 1095772..1096941 (-) 1170 WP_010905093.1 ring-cleaving dioxygenase -
  I6G22_RS05845 (I6G22_05850) - 1096992..1097613 (-) 622 Protein_1090 alpha/beta hydrolase -
  I6G22_RS05850 (I6G22_05855) - 1097644..1097841 (-) 198 WP_012896939.1 DUF4649 domain-containing protein -
  I6G22_RS05855 (I6G22_05860) - 1097969..1098436 (-) 468 WP_010905090.1 universal stress protein -

Sequence

Protein


Download         Length: 501 a.a.        Molecular weight: 56302.21 Da        Isoelectric Point: 8.9296

>NTDB_id=513723 I6G22_RS05830 WP_269670455.1 1093070..1094575(-) (comA) [Lactococcus lactis strain FDAARGOS_865]
MKFKKKNYTSQVDEMDCGCAALSMILKSYGTEKSLASLRLLAGTTIEGTSALGIKKAGEGLGFVVQVLRADASLFEMKKV
PYPFIAHVIKNQKYPHYYVITGANKNSVFIADPDPTVKMTKLSKEVFLSEWTGISLFLSPTPSYQPTKEKTSSLLSFIPI
ITRQKKVILNIVIASFIVTLINILGSYYLQSMIDSYIPNALMGTLGIISVGLLLTYIIQQVLEFAKAFLLNVLSQRLAID
VILSYIRHIFQLPMSFFSTRRTGEITSRFSDASSILDAIASTILSLFLDLTIVLMTGLILGLQNMQLFLLVLLAIPLYIV
VIIIFTPLFERQNHEVMQTNAILNSSIIEDINGIETIKALASEQERYQKIDYEFASYLKEAFTLQQSEAIQTAIKTTVQL
VLNVLILWFGATLVMHQKITLGQFITFNALLSYFTNPITNIINLQTKLQKARVANERLNEVYLVPSEFEEKKTELSLSHF
NLNMSEISYQFFHFLSFLLGG

Nucleotide


Download         Length: 1506 bp        

>NTDB_id=513723 I6G22_RS05830 WP_269670455.1 1093070..1094575(-) (comA) [Lactococcus lactis strain FDAARGOS_865]
ATGAAATTTAAAAAGAAAAATTATACCTCCCAAGTAGATGAAATGGATTGTGGATGTGCTGCTTTATCAATGATTTTAAA
ATCCTATGGGACAGAAAAATCGCTTGCCTCTCTTCGTTTACTTGCTGGTACAACAATCGAGGGAACTTCCGCTTTAGGAA
TAAAAAAAGCAGGAGAAGGTTTAGGTTTTGTAGTTCAAGTACTAAGAGCTGATGCAAGCCTTTTTGAAATGAAGAAAGTC
CCTTACCCTTTTATTGCTCATGTCATCAAGAACCAAAAGTATCCACACTACTATGTGATAACTGGCGCAAATAAAAATTC
GGTATTCATCGCAGATCCTGACCCAACCGTTAAAATGACAAAACTTTCAAAAGAAGTTTTCTTATCAGAGTGGACAGGCA
TTAGCTTATTTCTTTCACCTACCCCATCCTATCAGCCCACTAAAGAAAAAACTTCTTCATTATTATCTTTTATCCCAATT
ATCACCCGTCAAAAGAAAGTCATTCTCAATATTGTAATTGCCTCATTCATTGTAACGTTGATTAATATTCTAGGGTCTTA
CTACCTCCAGAGCATGATTGATAGTTACATTCCAAATGCCTTAATGGGAACTTTAGGGATTATCTCAGTAGGGCTATTGT
TAACTTATATTATCCAACAAGTCTTAGAGTTTGCTAAGGCTTTCTTACTAAACGTTCTTTCTCAAAGATTAGCCATTGAT
GTCATCCTTTCCTATATTAGACACATTTTCCAACTCCCGATGTCTTTCTTTTCGACTAGAAGAACAGGGGAAATTACCAG
TCGGTTTTCCGATGCCAGTTCTATTTTGGATGCTATTGCCTCAACGATTCTTTCGCTCTTTTTAGATTTAACCATTGTTC
TTATGACAGGACTGATTTTAGGGCTTCAAAATATGCAACTCTTTCTTCTCGTTCTTTTGGCAATCCCACTTTATATTGTT
GTTATTATTATTTTTACTCCGCTTTTTGAAAGACAAAATCATGAAGTTATGCAAACCAATGCCATCTTAAATTCCTCAAT
TATTGAAGACATTAATGGGATTGAAACCATCAAAGCGCTCGCCAGTGAACAAGAGAGATATCAAAAAATTGACTACGAAT
TTGCAAGTTATCTAAAAGAGGCTTTCACTTTACAACAGTCAGAAGCCATTCAGACGGCAATAAAAACGACAGTACAACTT
GTACTAAATGTTCTTATTTTATGGTTTGGTGCAACTTTAGTCATGCATCAAAAAATTACCCTCGGACAATTCATTACTTT
TAATGCCTTGCTTTCTTACTTTACAAATCCAATTACTAATATCATTAACCTTCAAACAAAACTACAAAAGGCAAGGGTAG
CCAATGAACGATTAAATGAGGTCTATCTTGTACCCAGTGAATTTGAAGAAAAGAAAACAGAACTGTCCCTCTCACATTTT
AATTTAAACATGTCTGAGATTTCATATCAATTCTTCCACTTTTTATCCTTCTTGTTGGGGGGGTAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(169-437)

Peptidase C39 family (Peptidase_C39)

(6-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B8QXL5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

60.243

98.403

0.593
  comA Streptococcus mitis NCTC 12261

57.685

100

0.577
  comA Streptococcus pneumoniae Rx1

57.809

98.403

0.569
  comA Streptococcus pneumoniae D39

57.809

98.403

0.569
  comA Streptococcus pneumoniae R6

57.809

98.403

0.569
  comA Streptococcus mitis SK321

57.809

98.403

0.569
  comA Streptococcus pneumoniae TIGR4

57.809

98.403

0.569
  comA/nlmT Streptococcus mutans UA159

56.478

98.603

0.557