Detailed information NTG0513711

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: I6G22_RS03105
• Genome accession: NZ_CP065737
• Coordinates: 563652..565862 (-)
• Length: 736 a.a.
• NCBI ID: WP_025016983.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain FDAARGOS_865
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 558652..570862

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G22_RS03075 (I6G22_03075)	atpA	558694..560196 (-)	1503	WP_004255265.1	F0F1 ATP synthase subunit alpha	-
I6G22_RS03080 (I6G22_03080)	-	560383..560910 (-)	528	WP_012898339.1	F0F1 ATP synthase subunit delta	-
I6G22_RS03085 (I6G22_03085)	atpF	560912..561418 (-)	507	WP_025016982.1	F0F1 ATP synthase subunit B	-
I6G22_RS03090 (I6G22_03090)	atpB	561433..562146 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
I6G22_RS03095 (I6G22_03095)	-	562191..562406 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
I6G22_RS03100 (I6G22_03100)	-	562591..563367 (-)	777	WP_023188533.1	alpha/beta hydrolase	-
I6G22_RS03105 (I6G22_03105)	comEC	563652..565862 (-)	2211	WP_025016983.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6G22_RS03110 (I6G22_03110)	comEA	565843..566490 (-)	648	WP_023188531.1	ComEA family DNA-binding protein	Machinery gene
I6G22_RS03115 (I6G22_03115)	-	566550..567911 (-)	1362	WP_025016984.1	ABC transporter permease	-
I6G22_RS03120 (I6G22_03120)	-	567908..568840 (-)	933	WP_025016985.1	ABC transporter ATP-binding protein	-
I6G22_RS03125 (I6G22_03125)	-	568945..569343 (-)	399	WP_025016986.1	hypothetical protein	-
I6G22_RS03130 (I6G22_03130)	-	569447..570010 (-)	564	WP_004255233.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84598.25 Da
• Isoelectric Point: 9.6911

>NTDB_id=513711 I6G22_RS03105 WP_025016983.1 563652..565862(-) (comEC) [Lactococcus lactis strain FDAARGOS_865]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLLCLILFIFSSLLASYRKYYLVIPFLLVMGSFFLVVKMDTIKNSENQPTTLS
KITMIPDTIQVNGDLLSFQGKERDQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQDI
YRQITIDKINKIVLNDTFDLRVLRRKAIVWSQTHFPKPMNDYMTGLLFGFLSKDFNQIGDIYSSLGIIHLFALLGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRLNPLDNLAVTTFLLMIVSPKFLLTTGGQLT
LFYAFVISMINHKFSELKGIRKLLTESSVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINHIFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLIDNLFKKRRQIIFAGLIVCSFFICKNPIYPSITAV
DIGQGDSIFLQDKFNKETILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANIAIHISKVGDKIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKVDVLKVGHHGSKTSSNSDFIKEINPKLALISVGEKNRYGHPNQETLETLKKNQIRILRTDQKGA
LKLMQINQQWRIRTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=513711 I6G22_RS03105 WP_025016983.1 563652..565862(-) (comEC) [Lactococcus lactis strain FDAARGOS_865]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTCAATTT
TAATTTACTTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTCATATAGAAAATATTATTTAGTCATCCCATTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAGTGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTACTAAGTTTTCAAGGAAAAGAAAGAGACCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGCCAGGATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCGTGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTCATTTTCCAAAGCCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATAGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATTGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCTT
TAGATAACCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAACAGGAGGACAACTAACT
TTATTTTATGCTTTTGTCATTTCAATGATTAATCATAAATTTTCAGAACTAAAAGGAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGCTTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGAACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATCATATTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCCTTACATTATCCTTTGGTTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTCTTTAAGAAAAGAA
GACAAATAATTTTTGCTGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAATTTACCCCAGTATCACAGCAGTT
GATATTGGTCAAGGAGATAGTATTTTTTTGCAAGATAAATTTAATAAAGAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAAATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAACTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATAAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTGAAAGTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACTCTGACTTTATTAAAGAAATTAATCCCAAACTTGCCCTCATTTCGGTTGGAGAGAAAAATCGAT
ATGGACATCCCAATCAAGAAACTTTAGAAACATTAAAAAAAAACCAAATCAGAATACTGAGAACCGATCAAAAGGGAGCG
CTTAAACTAATGCAAATCAATCAACAGTGGCGAATCCGAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (28-171)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

• Competence protein (Competence) (206-446)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	76.359	100	0.764
comEC/celB	Streptococcus mitis SK321	44.489	100	0.45
comEC/celB	Streptococcus mitis NCTC 12261	44.28	100	0.447
comEC/celB	Streptococcus pneumoniae TIGR4	43.28	100	0.438
comEC/celB	Streptococcus pneumoniae Rx1	42.876	100	0.433
comEC/celB	Streptococcus pneumoniae D39	42.876	100	0.433
comEC/celB	Streptococcus pneumoniae R6	42.876	100	0.433