Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   Y1U_RS08020 Genome accession   NC_017927
Coordinates   1535634..1537787 (-) Length   717 a.a.
NCBI ID   WP_014727675.1    Uniprot ID   -
Organism   Streptococcus thermophilus MN-ZLW-002     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1530634..1542787
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Y1U_RS07985 (Y1U_C1576) - 1530754..1530984 (-) 231 WP_014608662.1 bacteriocin class II family protein -
  Y1U_RS07990 (Y1U_C1577) - 1531340..1531540 (-) 201 WP_011681569.1 hypothetical protein -
  Y1U_RS07995 (Y1U_C1578) - 1531559..1531735 (-) 177 WP_011681570.1 Blp family class II bacteriocin -
  Y1U_RS08000 (Y1U_C1579) - 1531986..1532723 (+) 738 WP_011681571.1 LytR/AlgR family response regulator transcription factor -
  Y1U_RS11935 - 1533221..1534057 (+) 837 WP_232973989.1 ATP-binding protein -
  Y1U_RS08010 (Y1U_C1581) - 1534075..1534236 (-) 162 WP_011681573.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  Y1U_RS08015 (Y1U_C1582) - 1534251..1535618 (-) 1368 WP_011681574.1 bacteriocin secretion accessory protein -
  Y1U_RS08020 (Y1U_C1583) comA/nlmT 1535634..1537787 (-) 2154 WP_014727675.1 peptide cleavage/export ABC transporter Regulator
  Y1U_RS08025 (Y1U_C1586) - 1538867..1540612 (-) 1746 WP_014727676.1 ABC transporter ATP-binding protein -
  Y1U_RS08030 (Y1U_C1587) - 1540605..1542242 (-) 1638 WP_014727677.1 ABC transporter ATP-binding protein -
  Y1U_RS11940 (Y1U_C1588) - 1542551..1542757 (-) 207 WP_002948879.1 hypothetical protein -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80653.45 Da        Isoelectric Point: 6.9295

>NTDB_id=51346 Y1U_RS08020 WP_014727675.1 1535634..1537787(-) (comA/nlmT) [Streptococcus thermophilus MN-ZLW-002]
MFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRELAKTNKEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDV
PYPFIAHVNKDGKLQHYYVIYKSTKDYLIIGDPDPSVKVTKMTKERFEKEWTGVTLFMGPEPSYKPHKDKKNGLWDFLPL
IFKQRSLIANIVFASLLVTLINILGSYYLQGILDEYVPNQMKSTLGIISIGLVVTYVLQQMMTFARDYLLTILSHRFTID
VILSYIRHIFELPMSFFATRRTGEVISRFSDANSIIDALASTILSLFLDFSIVIIVGGVLLIQNSNLFKLVLCSVPIYTL
IVFAFMKPFERMNHDVMQSNAMVNSAIIEDINGIETIKSLTSEEVCYQKIDGEFIDYLDNSFRLSKLSILQTSLKQGAQL
ILNVLILWTGAQLVMGNTISIGQLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRLNEVYLIESEFGQSDDTYQEGIA
DGDITVTDLSYKYGFGRDTLTDVSLTIRQGEKISFVGVSGSGKTTLAKMLVNFYQPYKGHIDFNGQNISRIDKKTLRQHI
NYLPQQSYIFSGSVLENLTLGAARGITQADILKACEIAEIRQDIENMPMGFQTELSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKQVIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDHGRVVETGSHQDLMSYPGFYYQLFRK

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=51346 Y1U_RS08020 WP_014727675.1 1535634..1537787(-) (comA/nlmT) [Streptococcus thermophilus MN-ZLW-002]
ATGTTTCGTTTTCGTAGGACTTTTGTCCCTCAAATAGACATGAGGGATTGTGGAGTTGCTGCCTTGGCATCAGTGGCCAA
GTACTATGGTTCAGATTATTCATTAGCACATCTGCGTGAGTTGGCGAAGACCAATAAAGAAGGGACAACTGCCTTAGGTC
TTGTAGAGGCTGCTAAAAAAATTGGCTTTGAAACGAGAGCTATAAAGGCTGAAATGTCGCTCTTTGAGATGGAAGATGTT
CCTTATCCTTTTATTGCTCATGTTAATAAAGATGGGAAGCTTCAACATTATTATGTTATTTATAAAAGCACCAAGGATTA
TCTGATAATTGGAGACCCTGATCCAAGTGTAAAAGTAACTAAAATGACTAAAGAGCGTTTTGAGAAAGAGTGGACAGGTG
TTACTCTTTTTATGGGACCGGAACCCAGTTATAAACCACATAAGGATAAGAAAAATGGACTCTGGGACTTTCTCCCTTTG
ATCTTTAAACAAAGGTCCTTGATAGCTAATATTGTCTTTGCCAGTCTCTTGGTTACTTTAATAAATATTTTAGGTTCCTA
TTATTTACAAGGTATTCTAGACGAATATGTCCCTAATCAAATGAAGTCTACCTTAGGAATTATCTCAATTGGATTAGTTG
TGACCTATGTTTTACAACAAATGATGACTTTTGCAAGAGATTATCTCTTAACCATACTGAGTCATCGATTTACCATTGAC
GTTATCTTGTCCTACATACGACATATCTTTGAACTCCCAATGTCTTTTTTTGCCACAAGACGTACAGGGGAGGTTATCTC
ACGTTTTAGTGATGCTAACTCTATTATCGATGCTCTGGCTTCGACGATATTATCACTTTTCCTTGATTTCTCTATTGTGA
TTATCGTAGGAGGCGTGTTATTGATACAAAATAGCAATCTCTTCAAGCTAGTTCTTTGTTCGGTTCCAATTTATACCCTT
ATCGTCTTTGCCTTTATGAAACCTTTTGAGCGAATGAATCATGACGTCATGCAGAGTAATGCTATGGTTAATTCAGCCAT
CATTGAGGACATTAATGGGATTGAAACCATAAAGTCACTAACCAGCGAAGAAGTATGCTATCAAAAGATTGATGGTGAGT
TTATTGACTATCTAGACAATTCTTTTCGCCTTTCTAAGTTATCCATACTACAAACATCATTGAAACAAGGTGCTCAACTT
ATTTTAAATGTACTTATCCTCTGGACAGGTGCTCAGTTGGTGATGGGAAATACCATTTCGATAGGACAATTGATTACTTT
TAATATGTTGCTTTCTTACTTCACGAATCCTTTGGAAAATATCATTAACCTGCAAACCAAGTTACAGTCTGCTAAGGTAG
CTAATACTAGGCTCAATGAGGTCTATCTGATTGAATCAGAGTTTGGACAAAGTGATGATACCTATCAAGAAGGCATTGCG
GATGGAGATATCACTGTTACGGATTTATCTTATAAATATGGTTTTGGTCGTGATACTTTGACTGATGTCAGTTTGACGAT
TAGACAAGGAGAAAAAATCAGTTTTGTTGGTGTCAGTGGATCTGGTAAGACTACTCTAGCTAAAATGTTGGTCAATTTTT
ATCAACCATATAAGGGGCACATAGATTTTAATGGTCAAAATATTAGTCGCATAGACAAGAAAACTCTTCGTCAACATATT
AACTATCTCCCTCAGCAATCCTATATATTTAGTGGTAGTGTTTTAGAAAATCTTACTTTAGGTGCAGCACGGGGTATTAC
GCAAGCTGATATTTTGAAAGCTTGTGAAATAGCAGAAATTCGTCAAGATATTGAAAACATGCCTATGGGGTTTCAGACAG
AGCTGTCTGATGGAGCAGGTCTGTCTGGAGGGCAAAAGCAACGTATCGCTTTGGCGCGTGCACTACTAACGAAATCTCCT
GTACTAATCTTAGATGAAGCAACTAGCGGATTGGATGTTTTGACAGAAAAGCAGGTTATTGATAACCTCCTAGCACTAAA
AGATAAAACGATCATCTTTGTAGCACACAGGCTTAGTATCGCTGAGCGGACCGACCGTATCGTAGTCATTGATCACGGAC
GCGTAGTGGAGACAGGTTCTCATCAAGACCTAATGTCTTATCCAGGTTTCTATTATCAATTATTTAGAAAGTGA

Domains

Predicted by InterProScan.

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter transmembrane region (ABC_membrane)

(170-438)

ABC transporter (ABC_tran)

(500-649)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

67.787

99.582

0.675
  comA Streptococcus mitis NCTC 12261

65.963

99.163

0.654
  comA Streptococcus pneumoniae Rx1

65.541

99.163

0.65
  comA Streptococcus pneumoniae D39

65.541

99.163

0.65
  comA Streptococcus pneumoniae R6

65.541

99.163

0.65
  comA Streptococcus mitis SK321

65.26

99.163

0.647
  comA Streptococcus pneumoniae TIGR4

65.12

99.163

0.646
  comA Streptococcus gordonii str. Challis substr. CH1

63.866

99.582

0.636

Multiple sequence alignment