Detailed information NTG0513314

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: I6G42_RS07665
• Genome accession: NZ_CP065707
• Coordinates: 1570465..1571313 (-)
• Length: 282 a.a.
• NCBI ID: WP_038805368.1
• Uniprot ID: A0A7T3DY21
• Organism: Streptococcus oralis strain FDAARGOS_885
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1565465..1576313

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G42_RS07645 (I6G42_07645)	-	1566369..1567025 (-)	657	WP_038805364.1	MmcQ/YjbR family DNA-binding protein	-
I6G42_RS07650 (I6G42_07650)	-	1567069..1567701 (-)	633	WP_038805365.1	copper homeostasis protein CutC	-
I6G42_RS07655 (I6G42_07655)	-	1567794..1568153 (-)	360	WP_001220344.1	YbaN family protein	-
I6G42_RS07660 (I6G42_07660)	topA	1568259..1570346 (-)	2088	WP_038805367.1	type I DNA topoisomerase	-
I6G42_RS07665 (I6G42_07665)	dprA/cilB/dalA	1570465..1571313 (-)	849	WP_038805368.1	DNA-processing protein DprA	Machinery gene
I6G42_RS07670 (I6G42_07670)	lepA	1571480..1573303 (-)	1824	WP_038805369.1	translation elongation factor 4	-
I6G42_RS07675 (I6G42_07675)	-	1573382..1574110 (-)	729	WP_038805370.1	metallophosphoesterase family protein	-
I6G42_RS07680 (I6G42_07680)	recN	1574111..1575778 (-)	1668	WP_038805371.1	DNA repair protein RecN	-
I6G42_RS07685 (I6G42_07685)	-	1575785..1576216 (-)	432	WP_038805372.1	arginine repressor	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31289.74 Da
• Isoelectric Point: 5.0673

>NTDB_id=513314 I6G42_RS07665 WP_038805368.1 1570465..1571313(-) (dprA/cilB/dalA) [Streptococcus oralis strain FDAARGOS_885]
MKITNYEIYKLRKAGLTNQQILTVLEYDETVDQELLLGDIAEISGCRNPAVFMERYFQIDDAQLEKEFQKFPSFSILDDC
YPWDLSEIYDAPALLFYKGNLDLLKFPKVAVVGSRSCSSQGAKSVQKVIQGLENELIVVSGLAKGIDTAAHMAELQNGGR
TIAVIGTGLDVFYPRANKRLQEHIGNHHLVLSEYGPGEEPLKFHFPARNRIIAGLCRGVIVAEARMRSGSLITCERAMEE
GRDVFAIPGNILDGHSDGCHHLIQEGAKLISSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=513314 I6G42_RS07665 WP_038805368.1 1570465..1571313(-) (dprA/cilB/dalA) [Streptococcus oralis strain FDAARGOS_885]
ATGAAGATCACAAACTATGAGATTTACAAATTGAGAAAAGCTGGACTGACCAATCAACAAATTTTAACAGTTCTTGAATA
TGACGAGACTGTAGATCAGGAGCTCTTGCTAGGTGATATTGCTGAAATATCTGGGTGCCGTAATCCTGCTGTCTTTATGG
AACGCTATTTCCAGATAGATGATGCACAGTTGGAGAAGGAGTTCCAAAAATTTCCATCCTTCTCGATTCTTGATGACTGT
TATCCTTGGGATCTGAGTGAGATTTATGATGCTCCAGCGCTCTTGTTTTATAAAGGAAATCTGGACTTGTTGAAGTTTCC
AAAGGTTGCTGTTGTAGGGAGTCGTTCATGTTCTAGTCAGGGAGCAAAGTCGGTTCAGAAAGTCATTCAAGGTTTGGAAA
ACGAGTTAATCGTGGTCAGTGGTTTAGCCAAAGGGATTGATACGGCTGCCCATATGGCTGAACTCCAAAATGGAGGAAGA
ACGATTGCTGTCATTGGAACAGGGTTGGATGTTTTTTATCCCCGAGCCAATAAACGTTTGCAGGAACACATTGGCAATCA
CCATTTGGTACTTAGCGAGTACGGACCTGGTGAAGAACCCTTGAAATTTCACTTTCCAGCTCGTAATCGAATCATAGCAG
GACTGTGTCGCGGCGTTATTGTAGCAGAGGCAAGGATGCGTTCTGGTAGTCTCATCACTTGTGAGCGAGCTATGGAGGAA
GGGCGTGATGTTTTTGCCATTCCAGGAAACATTTTAGATGGCCATTCAGATGGCTGTCACCACCTGATCCAAGAGGGAGC
AAAGCTGATTTCCAGTGGTCAAGATGTGCTGGCTGAGTTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

3D structure

• AlphaFold DB: A0A7T3DY21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	91.135	100	0.911
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	90.78	100	0.908
dprA/cilB/dalA	Streptococcus pneumoniae D39	90.78	100	0.908
dprA/cilB/dalA	Streptococcus pneumoniae R6	90.78	100	0.908
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	90.78	100	0.908
dprA/cilB/dalA	Streptococcus mitis SK321	90.071	100	0.901
dprA	Streptococcus mutans UA159	60.714	99.291	0.603
dprA	Lactococcus lactis subsp. cremoris KW2	54.286	99.291	0.539