Detailed information NTG0513305

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: I6G42_RS05885
• Genome accession: NZ_CP065707
• Coordinates: 1205360..1207600 (+)
• Length: 746 a.a.
• NCBI ID: WP_038805080.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain FDAARGOS_885
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1200360..1212600

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G42_RS05855 (I6G42_05855)	-	1200867..1201472 (+)	606	WP_038805073.1	GrpB family protein	-
I6G42_RS05860 (I6G42_05860)	-	1201469..1201684 (+)	216	WP_038805074.1	YozE family protein	-
I6G42_RS05865 (I6G42_05865)	-	1201765..1202751 (+)	987	WP_038805075.1	PhoH family protein	-
I6G42_RS05870 (I6G42_05870)	ald	1202801..1203913 (-)	1113	WP_038805076.1	alanine dehydrogenase	-
I6G42_RS05875 (I6G42_05875)	-	1204090..1204659 (+)	570	WP_038805078.1	GNAT family N-acetyltransferase	-
I6G42_RS05880 (I6G42_05880)	comEA/celA/cilE	1204726..1205376 (+)	651	WP_038805079.1	helix-hairpin-helix domain-containing protein	Machinery gene
I6G42_RS05885 (I6G42_05885)	comEC/celB	1205360..1207600 (+)	2241	WP_038805080.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6G42_RS05890 (I6G42_05890)	infC	1207820..1208350 (+)	531	WP_000848184.1	translation initiation factor IF-3	-
I6G42_RS05895 (I6G42_05895)	rpmI	1208383..1208583 (+)	201	WP_001125942.1	50S ribosomal protein L35	-
I6G42_RS05900 (I6G42_05900)	rplT	1208635..1208994 (+)	360	WP_000124830.1	50S ribosomal protein L20	-
I6G42_RS05905 (I6G42_05905)	-	1209053..1209433 (+)	381	WP_038805081.1	VOC family protein	-
I6G42_RS05910 (I6G42_05910)	-	1209680..1210480 (+)	801	WP_038805082.1	dihydroorotate dehydrogenase electron transfer subunit	-
I6G42_RS05915 (I6G42_05915)	-	1210443..1211429 (+)	987	WP_080641291.1	dihydroorotate dehydrogenase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84494.79 Da
• Isoelectric Point: 9.2903

>NTDB_id=513305 I6G42_RS05885 WP_038805080.1 1205360..1207600(+) (comEC/celB) [Streptococcus oralis strain FDAARGOS_885]
MSQWIKNFPIPLIYLSFLLLWLYYAIFGASYLALLGFVFLLVCLFFQFPWKSAGKVLAICGVFGFWFLFQTWQQTQASQN
LVDSVEKVKILPDTIKVNGDSLSFRGKADGHTFQVYYKLQSEEEKEQFQTLTDLHEIELEGKVSEPEGQRNFGGFNYQAY
LKTQGIYQTLTIKRIQSVKQISSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDAFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGIKGLDNFALTVLVLFII
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDVVFLPLLSI
LFILSFVYPITQLNLVFEWLEDIIRLVSQLASRPLVFGQPNAWLLILLLISLAILYDFRKNIKRVAGVSLLIIGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKAILIDVGGKAESDKKIEKWQEKATTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGILTQKEFVAELEASQTKVRSVTAGENLPIFGSQLEVLSPRQIGDGDRDGSLVLYGKL
LDKHFLFTGNLKEKGEKDILKQYPNLEVDVLKVGQHGSKTSSNPAFLEKLKPEISLISVGKNNRAKLPHQETLTRLETIK
SKIYRTDQQGAIRFKGWNSWRIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=513305 I6G42_RS05885 WP_038805080.1 1205360..1207600(+) (comEC/celB) [Streptococcus oralis strain FDAARGOS_885]
ATGTCACAGTGGATTAAGAATTTCCCTATTCCTCTAATCTATCTGAGCTTTCTGTTGCTCTGGCTTTACTATGCCATTTT
TGGAGCGTCCTATCTCGCACTGCTAGGTTTTGTTTTTTTGCTCGTCTGTCTCTTTTTTCAATTTCCTTGGAAATCTGCTG
GAAAAGTTCTAGCGATTTGTGGAGTTTTTGGATTTTGGTTTCTGTTTCAAACTTGGCAACAGACACAAGCTAGTCAAAAC
CTAGTGGATTCTGTTGAAAAGGTGAAGATCTTGCCTGATACCATCAAAGTCAATGGAGACAGTCTGTCCTTTCGGGGCAA
GGCTGACGGCCATACCTTCCAAGTTTACTATAAACTCCAGTCTGAGGAGGAGAAAGAGCAATTTCAAACCTTAACAGATC
TTCATGAGATTGAACTAGAAGGGAAAGTTTCAGAGCCTGAAGGTCAGAGGAATTTTGGTGGATTTAACTACCAAGCCTAC
CTGAAGACTCAAGGGATTTACCAGACACTGACTATCAAGAGAATCCAGTCAGTTAAACAGATTAGCAGTTGGGATATAGG
TGAAAATTTATCAAGTTTACGTCGAAAGGCTGTAGTTTGGATCAAGACGCACTTTCCAGACCCTATGCGCAACTATATGA
CAGGTCTTCTGTTAGGACATCTGGATACGGACTTTGAGGAGATGAATGAACTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCTTGTCGGGTATGCAGGTGGGATTCTTTATGGATGCCTTTAAGAAACTCCTCTTGCGATTGGGCTTGACTCAAGA
AAAGTTGAAGTGGCTGACCTATCCCTTTTCCCTTATCTATGCAGGTCTGACAGGATTTTCAGCTTCAGTCATTCGCAGTC
TCTTGCAAAAGTTACTAGCACAACATGGTATTAAGGGCTTGGATAATTTTGCCTTGACAGTCCTTGTCCTCTTTATCATC
ATGCCCAACTTTTTCTTGACAGCTGGAGGGGTCTTGTCCTGCGCTTATGCTTTTATCTTGACTATGACAAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCCAGAGAAAGTTTGGTCATTTCCTTGGGAATATTGCCTATTTTGTCCTTTTATTTTGCAG
AATTTCAGCCTTGGTCAATTCTTTTAACCTTTGTCTTTTCCTTTCTGTTTGATGTTGTCTTCTTGCCGCTTTTGTCCATC
TTATTTATTCTGTCTTTTGTTTACCCAATCACCCAGCTTAACCTTGTCTTTGAGTGGTTGGAGGACATCATTCGCTTGGT
ATCGCAGCTGGCAAGCAGGCCCCTGGTCTTTGGTCAACCCAACGCATGGCTGTTGATTCTACTATTAATTTCCTTGGCAA
TACTGTATGATTTTAGGAAAAACATCAAAAGAGTAGCTGGAGTCAGCTTATTGATTATAGGTCTCTTTTTCCTAACCAAA
CATCCGCTGGAAAATGAAATCACCATGCTGGATGTCGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGTAAAGC
CATTCTCATAGATGTGGGAGGCAAGGCAGAGTCTGATAAGAAAATCGAAAAATGGCAAGAAAAGGCGACGACCAGCAATG
CCCAGAGAACCTTGATTCCCTATCTTAAAAGTCGTGGGGTAGCCAAGATTGACCAGCTGATTTTGACCAACACAGATAAA
GAACATGTTGGAGATTTGCTGGAGGTGACCAAGGCTTTCCATGTTGGGGAGATTTTAGTATCAAAAGGAATTCTGACACA
GAAGGAATTTGTAGCAGAACTAGAAGCAAGCCAAACCAAGGTGCGCAGTGTGACAGCAGGGGAGAACTTGCCAATTTTTG
GAAGTCAGTTAGAAGTCCTATCTCCAAGGCAGATTGGAGATGGAGATCGTGATGGTTCCCTGGTTCTTTATGGAAAACTT
TTGGATAAGCACTTTCTCTTTACAGGAAACTTGAAAGAGAAGGGAGAGAAGGATATTCTAAAGCAATACCCTAACTTAGA
GGTGGATGTCTTGAAAGTCGGTCAACATGGTTCTAAAACATCATCAAATCCAGCTTTTCTAGAAAAACTTAAACCAGAGA
TTTCTCTCATCTCAGTTGGAAAGAACAATCGTGCGAAACTCCCCCATCAGGAAACCTTGACTCGACTAGAGACCATCAAG
AGTAAGATTTACCGAACTGACCAGCAAGGAGCTATTCGCTTTAAAGGATGGAATAGTTGGCGAATTGAAACGGTTCGATA
A

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-457)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-638)

• Domain of unknown function (DUF4131) (DUF4131) (31-176)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	88.472	100	0.885
comEC/celB	Streptococcus mitis NCTC 12261	88.322	99.866	0.882
comEC/celB	Streptococcus pneumoniae TIGR4	86.997	100	0.87
comEC/celB	Streptococcus pneumoniae D39	86.595	100	0.866
comEC/celB	Streptococcus pneumoniae Rx1	86.595	100	0.866
comEC/celB	Streptococcus pneumoniae R6	86.595	100	0.866
comEC	Lactococcus lactis subsp. cremoris KW2	45.074	99.33	0.448