Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   I6G42_RS04245 Genome accession   NZ_CP065707
Coordinates   863330..865213 (+) Length   627 a.a.
NCBI ID   WP_038804822.1    Uniprot ID   A0A7T2ZYL1
Organism   Streptococcus oralis strain FDAARGOS_885     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 858330..870213
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G42_RS04230 (I6G42_04230) fmt 860336..861271 (+) 936 WP_000163668.1 methionyl-tRNA formyltransferase -
  I6G42_RS04235 (I6G42_04235) rsmB 861264..862577 (+) 1314 WP_038805610.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  I6G42_RS04240 (I6G42_04240) - 862593..863333 (+) 741 WP_038804821.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  I6G42_RS04245 (I6G42_04245) stkP 863330..865213 (+) 1884 WP_038804822.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  I6G42_RS04250 (I6G42_04250) - 865301..866059 (+) 759 WP_038804824.1 threonine/serine exporter family protein -
  I6G42_RS04255 (I6G42_04255) - 866061..866516 (+) 456 WP_038804825.1 threonine/serine exporter family protein -
  I6G42_RS04260 (I6G42_04260) - 866635..867807 (+) 1173 WP_038805611.1 hydroxymethylglutaryl-CoA synthase -
  I6G42_RS04265 (I6G42_04265) - 867807..869081 (+) 1275 WP_038804826.1 hydroxymethylglutaryl-CoA reductase, degradative -
  I6G42_RS04270 (I6G42_04270) - 869223..870188 (-) 966 WP_000225991.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 68374.68 Da        Isoelectric Point: 9.2160

>NTDB_id=513298 I6G42_RS04245 WP_038804822.1 863330..865213(+) (stkP) [Streptococcus oralis strain FDAARGOS_885]
MIQIGKIFAGRYRIIKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHSPLSNEEAVRIMGQILLAMRLAHTRGIIHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPAVP
QALENVVIKATAKKLTDRYQSVSEMYVDLSSCLSHNRRREPKLVFDEASKVDTKTLPKVPQSTLTSIPKAKPQLERPQSK
QQTQQVVDEAPVPKPAKKRKFKARYMILLASALLVAASLIWIFSRTPATIAIPDVSGQTVAEAKETLKKANFEVGEEKTE
ASDTVAEGRVIRTDPEARSGRKEGSKVNLIVSSGKQSFQLSNYVGRKSSDVVAELKEKKVPENLIKIEEEESSESDPGTV
IRQTPAAGSTYDLTKASTITLTVAKKVTSVSMPSYIGSSLEFTKNNLTQIVGVKEANIEVVEVSTAPEGTTAGTVVSQDP
KPGEKVDLNKTRVKISIYKPKPLPSSSSSSQHGNSGTDTTPSQSNNQGSNPTTDSSDGSRTSSNERN

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=513298 I6G42_RS04245 WP_038804822.1 863330..865213(+) (stkP) [Streptococcus oralis strain FDAARGOS_885]
ATGATCCAGATCGGCAAGATTTTTGCCGGACGATATCGGATTATCAAACAGATTGGTCGAGGAGGCATGGCGGATGTTTA
CTTGGCCAAGGATTTGATCCTAGACGGGGAAGAAGTGGCGGTTAAGGTCCTGAGGACTAACTATCAGACAGATCCGATTG
CTGTGGCACGTTTTCAACGTGAAGCGAGAGCCATGGCGGATCTGGATCATCCCCATATCGTTCGAATAACAGATATCGGT
GAAGAAGACGGTCAGCAGTATCTGGCTATGGAGTATGTGGCAGGGCTTGATCTCAAACGTTATATCAAAGAACACTCCCC
TCTCTCAAACGAAGAAGCCGTCCGTATTATGGGACAGATTCTCTTGGCGATGCGTCTGGCGCATACGAGAGGGATTATCC
ACCGAGATTTGAAACCTCAAAATATCCTATTGACACCAGATGGAACTGCCAAAGTTACAGACTTTGGGATTGCCGTGGCT
TTTGCAGAGACCAGTCTGACACAGACTAACTCCATGCTCGGTTCAGTCCACTATCTCTCACCTGAGCAGGCCCGTGGTTC
CAAGGCAACTGTGCAGAGTGACATCTATGCTATGGGGATTATTTTCTATGAGATGTTGACAGGACATATCCCTTATGATG
GGGATAGTGCAGTGACTATTGCCCTCCAGCATTTCCAAAAACCACTTCCATCTGTTATTGCTGAGAATCCAGCAGTACCA
CAAGCTTTGGAAAATGTTGTTATCAAGGCAACGGCCAAGAAATTGACAGATCGCTATCAGTCTGTATCAGAAATGTATGT
GGACTTGTCAAGTTGTTTGTCTCACAATCGTAGGAGAGAACCAAAGCTAGTCTTTGATGAGGCAAGCAAGGTTGATACCA
AGACCTTGCCTAAAGTTCCACAAAGCACTCTGACCTCTATTCCGAAGGCTAAGCCACAATTAGAGCGACCTCAATCAAAA
CAGCAGACTCAGCAGGTGGTAGATGAAGCACCAGTACCAAAACCAGCGAAAAAACGGAAGTTTAAAGCTCGCTACATGAT
TTTACTGGCCAGTGCCTTGCTAGTTGCAGCCTCTTTGATTTGGATCTTCTCCCGAACTCCAGCGACTATTGCTATTCCAG
ATGTATCGGGACAGACAGTTGCTGAAGCTAAAGAGACACTGAAGAAAGCTAATTTTGAAGTAGGTGAAGAAAAGACAGAG
GCCAGCGACACAGTAGCCGAAGGTCGCGTCATTCGAACAGATCCAGAAGCTAGAAGCGGTCGAAAAGAAGGAAGCAAAGT
AAATCTAATCGTTTCATCAGGTAAGCAATCCTTCCAACTAAGTAACTATGTAGGACGTAAGTCCTCGGATGTTGTCGCGG
AGCTCAAAGAGAAAAAGGTTCCAGAAAACCTCATTAAGATCGAGGAAGAGGAATCTAGCGAAAGCGATCCAGGAACAGTC
ATTAGGCAAACCCCAGCTGCAGGAAGCACTTACGATCTCACGAAAGCCAGCACGATTACCTTAACAGTTGCTAAGAAGGT
AACCAGCGTTTCGATGCCAAGTTACATTGGTTCAAGTCTCGAATTTACTAAGAACAATTTGACTCAGATTGTTGGTGTAA
AAGAGGCCAATATCGAAGTTGTGGAAGTATCAACTGCTCCTGAAGGAACTACTGCAGGAACAGTTGTTAGTCAGGACCCT
AAACCTGGAGAAAAGGTAGATCTCAATAAAACACGTGTTAAGATTTCTATTTATAAACCAAAACCACTTCCTTCTTCATC
AAGTTCGTCTCAACACGGAAATTCAGGAACAGACACGACGCCTTCACAGAGTAACAATCAAGGTAGCAACCCTACAACGG
ATTCTTCAGATGGCAGTAGAACGTCAAGTAATGAACGAAATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(371-432)

PASTA domain (PASTA)

(510-579)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T2ZYL1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

77.187

92.982

0.718
  stkP Streptococcus pneumoniae D39

76.844

92.982

0.715
  stkP Streptococcus pneumoniae R6

76.844

92.982

0.715
  stkP Streptococcus pneumoniae Rx1

76.672

92.982

0.713
  pknB Streptococcus mutans UA159

56.282

92.663

0.522
  stkP/pknB Streptococcus salivarius strain HSISS4

50.918

95.534

0.486