Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   I6G43_RS06600 Genome accession   NZ_CP065706
Coordinates   1376172..1376912 (-) Length   246 a.a.
NCBI ID   WP_000782713.1    Uniprot ID   A0A7T3DUI5
Organism   Streptococcus oralis strain FDAARGOS_886     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1371172..1381912
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G43_RS06585 (I6G43_06585) msrB 1372677..1373615 (-) 939 WP_000818183.1 peptide-methionine (R)-S-oxide reductase MsrB -
  I6G43_RS06590 (I6G43_06590) thrB 1373866..1374735 (-) 870 WP_000692411.1 homoserine kinase -
  I6G43_RS06595 (I6G43_06595) - 1374737..1376023 (-) 1287 WP_000216343.1 homoserine dehydrogenase -
  I6G43_RS06600 (I6G43_06600) mecA 1376172..1376912 (-) 741 WP_000782713.1 adaptor protein MecA Regulator
  I6G43_RS06605 (I6G43_06605) - 1377035..1378513 (+) 1479 WP_000789698.1 oligosaccharide flippase family protein -
  I6G43_RS06610 (I6G43_06610) - 1378561..1381086 (-) 2526 WP_000792194.1 MBL fold metallo-hydrolase -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28555.33 Da        Isoelectric Point: 4.0799

>NTDB_id=513229 I6G43_RS06600 WP_000782713.1 1376172..1376912(-) (mecA) [Streptococcus oralis strain FDAARGOS_886]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLTDLPDMEELAQMSPDEFLKTLEKSIAEKTKDDIEAIQSLEQVEAKEEEQEQADKETESKKEPYIYYILRFA
SLADLVAFSKTVNYQMETSELYKMNGYYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGRILINHDAVLG
LQKVNS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=513229 I6G43_RS06600 WP_000782713.1 1376172..1376912(-) (mecA) [Streptococcus oralis strain FDAARGOS_886]
ATGAAGATGAAACAAATTAGTGATACAACACTGAAAATCACGATGACTTTAGATGATTTGATGGATCGGGGAATGGAAAT
CGCAGACTTTCTTGTTCCTCAGGAAAAAACAGAAGAGTTTTTCTATGCTATTTTAGATGAATTAGAGATGCCAGACAATT
TCTTGGATAGTGGCATGCTGAGTTTTCGTGTGACGCCAAAACCTGATAAGGTCGATGTCTTTGTGACCAAGTCTAAGATT
GACCAAAATCTAGATTTTGAAGATTTGACGGATCTGCCAGATATGGAAGAATTGGCCCAAATGTCGCCGGACGAATTTCT
CAAAACATTGGAAAAGAGTATTGCAGAAAAGACCAAAGATGATATTGAGGCCATCCAGTCTCTAGAACAGGTAGAAGCTA
AAGAAGAAGAGCAAGAGCAGGCGGACAAGGAAACTGAGAGCAAGAAAGAACCTTATATCTACTATATCCTGCGCTTTGCA
AGCCTTGCTGACTTAGTTGCTTTTTCAAAGACGGTTAACTACCAGATGGAAACATCTGAACTCTATAAGATGAATGGATA
CTATTATTTGACAATCTTAGTCGATGTTGAAAATCATCCTAGTCCATATCCAGCCTGGCTCTTGGCTCGTATGCGTGAGT
TTGCAGACGACAGTGATATCAGTCGTTCGGTTTTACAAGAGTATGGTCGCATCTTGATTAATCACGACGCTGTGCTCGGT
CTTCAAAAAGTTAATTCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T3DUI5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

88.98

99.593

0.886
  mecA Streptococcus pneumoniae D39

88.98

99.593

0.886
  mecA Streptococcus pneumoniae R6

88.98

99.593

0.886
  mecA Streptococcus pneumoniae TIGR4

88.571

99.593

0.882
  mecA Streptococcus thermophilus LMD-9

46.988

100

0.476
  mecA Streptococcus mutans UA159

47.755

99.593

0.476
  mecA Streptococcus thermophilus LMG 18311

46.586

100

0.472