Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   I6G43_RS06090 Genome accession   NZ_CP065706
Coordinates   1280636..1281484 (-) Length   282 a.a.
NCBI ID   WP_000705335.1    Uniprot ID   A0A7T2ZM88
Organism   Streptococcus oralis strain FDAARGOS_886     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1275636..1286484
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G43_RS06070 (I6G43_06070) - 1276541..1277197 (-) 657 WP_038806051.1 MmcQ/YjbR family DNA-binding protein -
  I6G43_RS06075 (I6G43_06075) - 1277241..1277873 (-) 633 WP_000638782.1 copper homeostasis protein CutC -
  I6G43_RS06080 (I6G43_06080) - 1277966..1278325 (-) 360 WP_001211121.1 YbaN family protein -
  I6G43_RS06085 (I6G43_06085) topA 1278431..1280518 (-) 2088 WP_000179667.1 type I DNA topoisomerase -
  I6G43_RS06090 (I6G43_06090) dprA/cilB/dalA 1280636..1281484 (-) 849 WP_000705335.1 DNA-processing protein DprA Machinery gene
  I6G43_RS06095 (I6G43_06095) lepA 1281652..1283475 (-) 1824 WP_001047195.1 translation elongation factor 4 -
  I6G43_RS06100 (I6G43_06100) - 1283554..1284282 (-) 729 WP_038806050.1 metallophosphoesterase family protein -
  I6G43_RS06105 (I6G43_06105) recN 1284283..1285950 (-) 1668 WP_038806049.1 DNA repair protein RecN -
  I6G43_RS06110 (I6G43_06110) - 1285957..1286388 (-) 432 WP_001034389.1 arginine repressor -

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31206.69 Da        Isoelectric Point: 4.9345

>NTDB_id=513227 I6G43_RS06090 WP_000705335.1 1280636..1281484(-) (dprA/cilB/dalA) [Streptococcus oralis strain FDAARGOS_886]
MKITNYEIYKLRKAGLTNQQILTVLEYDETVDQELLLGDIAEISGCRNPAVFMERYFQIDDAQLEKEFQKFPSFSILDDC
YPWDLSEIYDAPALLFYKGNLDLLKFPKVAVVGSRSCSSQGAKSVQRVIQGLENELIVVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQEYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEARMRSGSLITCERAMEE
GRDVFAIPGNILDGHSDGCHHLIQEGAKLISSGQDVLAEFEF

Nucleotide


Download         Length: 849 bp        

>NTDB_id=513227 I6G43_RS06090 WP_000705335.1 1280636..1281484(-) (dprA/cilB/dalA) [Streptococcus oralis strain FDAARGOS_886]
ATGAAGATAACAAACTATGAGATTTACAAATTGAGAAAAGCAGGGCTGACCAATCAACAAATTTTAACTGTCCTTGAATA
TGACGAGACTGTAGATCAAGAACTTTTATTAGGAGATATTGCAGAAATCTCTGGTTGCAGAAATCCCGCTGTCTTTATGG
AACGCTATTTCCAGATAGATGATGCACAGTTGGAGAAAGAGTTCCAAAAATTTCCATCCTTCTCGATTCTTGATGACTGT
TATCCTTGGGATCTGAGTGAGATTTATGATGCTCCAGCGCTCTTGTTTTATAAGGGAAATCTAGACTTGCTGAAGTTTCC
AAAGGTTGCTGTTGTAGGGAGCCGTTCATGTTCTAGTCAGGGAGCAAAGTCGGTTCAGAGAGTCATTCAAGGTTTGGAAA
ACGAGTTAATCGTGGTCAGTGGTTTGGCTAAAGGGATTGATACGGCTGCCCACATGGCTGCACTCCAGAATGGTGGAAAA
ACGATTGCTGTGATTGGAACAGGATTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAGGAGTATATTGGCAATGA
CCATCTGGTTCTCAGTGAATATGGACCTGGCGAGCAACCTCTGAAATTTCATTTTCCAGCTCGAAATCGTATCATTGCAG
GACTTTGCCGTGGAGTTATTGTAGCAGAGGCAAGAATGCGTTCAGGGAGTCTCATCACCTGTGAGCGAGCTATGGAGGAA
GGTCGCGATGTCTTTGCTATTCCAGGGAACATTCTTGATGGCCATTCAGATGGTTGCCACCACTTGATCCAAGAGGGGGC
AAAACTGATTTCCAGCGGTCAAGATGTGCTGGCTGAGTTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(3-64)

DNA recombination-mediator protein A (DNA_processg_A)

(75-271)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T2ZM88

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

92.908

100

0.929
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

92.553

100

0.926
  dprA/cilB/dalA Streptococcus pneumoniae D39

92.553

100

0.926
  dprA/cilB/dalA Streptococcus pneumoniae R6

92.553

100

0.926
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

92.553

100

0.926
  dprA/cilB/dalA Streptococcus mitis SK321

91.844

100

0.918
  dprA Streptococcus mutans UA159

61.429

99.291

0.61
  dprA Lactococcus lactis subsp. cremoris KW2

54.643

99.291

0.543