Detailed information NTG0513218

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: I6G43_RS04425
• Genome accession: NZ_CP065706
• Coordinates: 933003..935243 (+)
• Length: 746 a.a.
• NCBI ID: WP_038805080.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain FDAARGOS_886
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 928003..940243

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G43_RS04395 (I6G43_04395)	-	928498..929076 (+)	579	WP_009014028.1	GrpB family protein	-
I6G43_RS04400 (I6G43_04400)	-	929100..929315 (+)	216	WP_001232084.1	YozE family protein	-
I6G43_RS04405 (I6G43_04405)	-	929396..930382 (+)	987	WP_000658176.1	PhoH family protein	-
I6G43_RS04410 (I6G43_04410)	ald	930444..931556 (-)	1113	WP_038806202.1	alanine dehydrogenase	-
I6G43_RS04415 (I6G43_04415)	-	931733..932302 (+)	570	WP_038805078.1	GNAT family N-acetyltransferase	-
I6G43_RS04420 (I6G43_04420)	comEA/celA/cilE	932369..933019 (+)	651	WP_038805079.1	helix-hairpin-helix domain-containing protein	Machinery gene
I6G43_RS04425 (I6G43_04425)	comEC/celB	933003..935243 (+)	2241	WP_038805080.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I6G43_RS04430 (I6G43_04430)	infC	935463..935993 (+)	531	WP_000848184.1	translation initiation factor IF-3	-
I6G43_RS04435 (I6G43_04435)	rpmI	936026..936226 (+)	201	WP_001125942.1	50S ribosomal protein L35	-
I6G43_RS04440 (I6G43_04440)	rplT	936278..936637 (+)	360	WP_000124830.1	50S ribosomal protein L20	-
I6G43_RS04445 (I6G43_04445)	-	936696..937076 (+)	381	WP_038806201.1	VOC family protein	-
I6G43_RS04450 (I6G43_04450)	-	937323..938123 (+)	801	WP_038806200.1	dihydroorotate dehydrogenase electron transfer subunit	-
I6G43_RS04455 (I6G43_04455)	-	938086..939072 (+)	987	WP_161603075.1	dihydroorotate dehydrogenase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84494.79 Da
• Isoelectric Point: 9.2903

>NTDB_id=513218 I6G43_RS04425 WP_038805080.1 933003..935243(+) (comEC/celB) [Streptococcus oralis strain FDAARGOS_886]
MSQWIKNFPIPLIYLSFLLLWLYYAIFGASYLALLGFVFLLVCLFFQFPWKSAGKVLAICGVFGFWFLFQTWQQTQASQN
LVDSVEKVKILPDTIKVNGDSLSFRGKADGHTFQVYYKLQSEEEKEQFQTLTDLHEIELEGKVSEPEGQRNFGGFNYQAY
LKTQGIYQTLTIKRIQSVKQISSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDAFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGIKGLDNFALTVLVLFII
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDVVFLPLLSI
LFILSFVYPITQLNLVFEWLEDIIRLVSQLASRPLVFGQPNAWLLILLLISLAILYDFRKNIKRVAGVSLLIIGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKAILIDVGGKAESDKKIEKWQEKATTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGILTQKEFVAELEASQTKVRSVTAGENLPIFGSQLEVLSPRQIGDGDRDGSLVLYGKL
LDKHFLFTGNLKEKGEKDILKQYPNLEVDVLKVGQHGSKTSSNPAFLEKLKPEISLISVGKNNRAKLPHQETLTRLETIK
SKIYRTDQQGAIRFKGWNSWRIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=513218 I6G43_RS04425 WP_038805080.1 933003..935243(+) (comEC/celB) [Streptococcus oralis strain FDAARGOS_886]
ATGTCACAGTGGATTAAGAATTTCCCTATTCCTCTAATCTATCTGAGCTTTCTGTTGCTCTGGCTTTACTATGCCATTTT
TGGAGCGTCCTATCTCGCACTGCTAGGTTTTGTTTTTTTGCTCGTCTGTCTCTTTTTTCAATTTCCTTGGAAATCTGCTG
GAAAAGTTCTAGCGATTTGTGGAGTTTTTGGATTTTGGTTTCTGTTTCAAACTTGGCAACAGACACAAGCTAGTCAAAAC
CTAGTGGATTCTGTTGAAAAGGTGAAGATCTTGCCTGATACCATCAAAGTCAATGGAGACAGTCTGTCCTTTCGGGGCAA
GGCTGACGGCCATACCTTCCAAGTTTACTATAAACTCCAGTCTGAGGAGGAGAAAGAGCAATTTCAAACCTTAACAGATC
TTCATGAGATTGAACTAGAAGGGAAAGTTTCAGAGCCTGAAGGTCAGAGGAATTTTGGTGGATTTAACTACCAAGCCTAC
CTGAAGACTCAAGGGATTTACCAGACACTGACTATCAAGAGAATCCAGTCAGTTAAACAGATTAGCAGTTGGGATATAGG
TGAAAATTTATCAAGTTTACGTCGAAAGGCTGTAGTTTGGATCAAGACGCACTTTCCAGACCCTATGCGCAACTATATGA
CAGGTCTTCTGTTAGGACATCTGGATACGGACTTTGAGGAGATGAATGAACTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCTTGTCGGGTATGCAGGTGGGATTCTTTATGGATGCCTTTAAGAAACTCCTCTTGCGATTGGGCTTGACTCAAGA
AAAGTTGAAGTGGCTGACCTATCCCTTTTCCCTTATCTATGCAGGTCTGACAGGATTTTCAGCTTCAGTCATTCGCAGTC
TCTTGCAAAAGTTACTAGCACAACATGGTATTAAGGGCTTGGATAATTTTGCCTTGACAGTCCTTGTCCTCTTTATCATC
ATGCCCAACTTTTTCTTGACAGCTGGAGGGGTCTTGTCCTGCGCTTATGCTTTTATCTTGACTATGACAAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCCAGAGAAAGTTTGGTCATTTCCTTGGGAATATTGCCTATTTTGTCCTTTTATTTTGCAG
AATTTCAGCCTTGGTCAATTCTTTTAACCTTTGTCTTTTCCTTTCTGTTTGATGTTGTCTTCTTGCCGCTTTTGTCCATC
TTATTTATTCTGTCTTTTGTTTACCCAATCACCCAGCTTAACCTTGTCTTTGAGTGGTTGGAGGACATCATTCGCTTGGT
ATCGCAGCTGGCAAGCAGGCCCCTGGTCTTTGGTCAACCCAACGCATGGCTGTTGATTCTACTATTAATTTCCTTGGCAA
TACTGTATGATTTTAGGAAAAACATCAAAAGAGTAGCTGGAGTCAGCTTATTGATTATAGGTCTCTTTTTCCTAACCAAA
CATCCGCTGGAAAATGAAATCACCATGCTGGATGTCGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGTAAAGC
CATTCTCATAGATGTGGGAGGCAAGGCAGAGTCTGATAAGAAAATCGAAAAATGGCAAGAAAAGGCGACGACCAGCAATG
CCCAGAGAACCTTGATTCCCTATCTTAAAAGTCGTGGGGTAGCCAAGATTGACCAGCTGATTTTGACCAACACAGATAAA
GAACATGTTGGAGATTTGCTGGAGGTGACCAAGGCTTTCCATGTTGGGGAGATTTTAGTATCAAAAGGAATTCTGACACA
GAAGGAATTTGTAGCAGAACTAGAAGCAAGCCAAACCAAGGTGCGCAGTGTGACAGCAGGGGAGAACTTGCCAATTTTTG
GAAGTCAGTTAGAAGTCCTATCTCCAAGGCAGATTGGAGATGGAGATCGTGATGGTTCCCTGGTTCTTTATGGAAAACTT
TTGGATAAGCACTTTCTCTTTACAGGAAACTTGAAAGAGAAGGGAGAGAAGGATATTCTAAAGCAATACCCTAACTTAGA
GGTGGATGTCTTGAAAGTCGGTCAACATGGTTCTAAAACATCATCAAATCCAGCTTTTCTAGAAAAACTTAAACCAGAGA
TTTCTCTCATCTCAGTTGGAAAGAACAATCGTGCGAAACTCCCCCATCAGGAAACCTTGACTCGACTAGAGACCATCAAG
AGTAAGATTTACCGAACTGACCAGCAAGGAGCTATTCGCTTTAAAGGATGGAATAGTTGGCGAATTGAAACGGTTCGATA
A

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-457)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-638)

• Domain of unknown function (DUF4131) (DUF4131) (31-176)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	88.472	100	0.885
comEC/celB	Streptococcus mitis NCTC 12261	88.322	99.866	0.882
comEC/celB	Streptococcus pneumoniae TIGR4	86.997	100	0.87
comEC/celB	Streptococcus pneumoniae D39	86.595	100	0.866
comEC/celB	Streptococcus pneumoniae Rx1	86.595	100	0.866
comEC/celB	Streptococcus pneumoniae R6	86.595	100	0.866
comEC	Lactococcus lactis subsp. cremoris KW2	45.074	99.33	0.448