Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   I6G43_RS02705 Genome accession   NZ_CP065706
Coordinates   573817..575700 (+) Length   627 a.a.
NCBI ID   WP_038806374.1    Uniprot ID   A0A7T3DWA0
Organism   Streptococcus oralis strain FDAARGOS_886     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 568817..580700
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G43_RS02690 (I6G43_02690) fmt 570823..571758 (+) 936 WP_038806375.1 methionyl-tRNA formyltransferase -
  I6G43_RS02695 (I6G43_02695) rsmB 571751..573064 (+) 1314 WP_009014086.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  I6G43_RS02700 (I6G43_02700) - 573080..573820 (+) 741 WP_000401536.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  I6G43_RS02705 (I6G43_02705) stkP 573817..575700 (+) 1884 WP_038806374.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  I6G43_RS02710 (I6G43_02710) - 575788..576546 (+) 759 WP_038806373.1 threonine/serine exporter family protein -
  I6G43_RS02715 (I6G43_02715) - 576548..577003 (+) 456 WP_000176903.1 threonine/serine exporter family protein -
  I6G43_RS02720 (I6G43_02720) - 577122..578294 (+) 1173 WP_025168409.1 hydroxymethylglutaryl-CoA synthase -
  I6G43_RS02725 (I6G43_02725) - 578294..579568 (+) 1275 WP_038806372.1 hydroxymethylglutaryl-CoA reductase, degradative -
  I6G43_RS02730 (I6G43_02730) - 579710..580675 (-) 966 WP_000225991.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 68400.76 Da        Isoelectric Point: 9.2125

>NTDB_id=513211 I6G43_RS02705 WP_038806374.1 573817..575700(+) (stkP) [Streptococcus oralis strain FDAARGOS_886]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMAELDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHSPLSNEEAVRIMGQILLAMRLAHTRGIIHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPAVP
QALENVVIKATAKKLTDRYQSVSEMYVDLSSCLSHNRRREPKLVFDEASKVDTKTLPKVPQSTLTSIPKAKPQLERPQSK
EQTQQVVDEAPVPKPAKKRKFKARYMILLASALLVAASLIWIFSRTPATIAIPDVSGQTVAEAKENLKKSNFEAGEEKSE
ASETVAEGRVIRTDPEAGSGRKEGSKVNLIVSSGKQSFKLSNYVGRKSSDVVAELKEKKVPENLIKIEEEETSESDPGTV
IRQTPAAGSTYDLTKATSIVLTVAKKVTSVSMPSYIGSSLEFTKNNLIQIVGVKEANIEVVEVSTAPEGTTAGTVVSQDP
KPGEKVDLNKTRVKISIYKPKPLPSSSSSSQHRNPGTDTTPSQSNNQGSNSTTDSSDGSRTSSNERN

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=513211 I6G43_RS02705 WP_038806374.1 573817..575700(+) (stkP) [Streptococcus oralis strain FDAARGOS_886]
ATGATCCAGATCGGCAAGATTTTTGCCGGACGATATCGGATTGTCAAACAGATTGGTCGAGGAGGCATGGCAGATGTTTA
CTTGGCCAAGGATTTGATCCTAGACGGGGAAGAAGTGGCGGTTAAGGTCCTGAGGACTAACTATCAGACAGATCCGATTG
CTGTGGCACGTTTTCAACGTGAAGCGAGAGCCATGGCGGAACTGGATCATCCCCATATCGTTCGAATAACAGATATCGGT
GAGGAAGACGGTCAGCAGTACCTAGCTATGGAGTATGTAGCAGGGCTTGACCTCAAACGTTATATCAAAGAACACTCCCC
TCTTTCAAATGAAGAAGCCGTCCGTATTATGGGACAGATTCTCTTGGCGATGCGTCTGGCGCATACGAGAGGGATTATCC
ACCGAGATTTGAAACCTCAAAATATCCTATTGACACCAGATGGAACTGCCAAAGTTACAGACTTTGGGATTGCCGTGGCT
TTTGCAGAGACCAGTCTGACACAGACCAACTCCATGCTCGGTTCAGTCCACTATCTCTCACCTGAGCAGGCCCGTGGTTC
CAAGGCAACTGTGCAGAGTGATATCTATGCTATGGGGATTATTTTCTATGAAATGTTGACTGGACATATCCCTTATGATG
GGGATAGTGCAGTGACTATTGCCCTCCAGCATTTCCAAAAACCACTTCCATCTGTTATTGCTGAGAATCCAGCAGTGCCA
CAAGCTTTGGAAAATGTTGTTATCAAGGCAACGGCCAAGAAATTGACAGATCGCTATCAGTCTGTATCAGAAATGTATGT
GGACTTGTCGAGTTGTTTGTCTCACAATCGTAGGAGAGAACCAAAGCTAGTCTTTGATGAGGCAAGCAAGGTTGATACCA
AGACCTTGCCTAAAGTTCCACAAAGCACTCTGACCTCTATTCCGAAAGCTAAGCCACAATTAGAGCGACCTCAATCAAAA
GAGCAGACTCAGCAGGTGGTAGATGAAGCACCAGTACCAAAACCAGCGAAAAAACGGAAGTTTAAAGCTCGCTACATGAT
TTTACTGGCCAGTGCCTTGCTAGTTGCAGCCTCTTTGATTTGGATCTTCTCCCGAACTCCAGCGACTATTGCCATTCCAG
ATGTATCGGGGCAGACAGTAGCAGAGGCCAAAGAAAACCTTAAAAAGTCCAATTTTGAAGCAGGCGAGGAAAAATCAGAG
GCAAGTGAGACGGTTGCTGAAGGTCGCGTCATTCGAACAGACCCAGAAGCTGGAAGCGGTCGAAAAGAAGGAAGCAAAGT
AAATCTAATCGTGTCTTCAGGTAAGCAATCCTTCAAACTAAGTAACTATGTAGGACGTAAGTCCTCGGATGTTGTCGCAG
AGCTCAAAGAGAAAAAGGTTCCAGAAAATCTTATCAAGATCGAGGAAGAAGAAACAAGTGAGAGCGATCCGGGCACAGTT
ATTAGACAAACCCCAGCTGCAGGAAGTACGTATGATTTGACCAAGGCAACCAGTATTGTTTTGACAGTCGCTAAGAAAGT
AACCAGCGTTTCCATGCCAAGTTACATTGGCTCCAGTCTCGAATTTACGAAAAATAATTTGATTCAAATTGTTGGTGTAA
AAGAGGCCAATATCGAAGTTGTGGAAGTATCGACTGCTCCTGAAGGAACTACTGCAGGAACCGTTGTTAGTCAGGACCCT
AAACCTGGAGAAAAGGTAGATCTCAATAAAACACGTGTTAAGATTTCGATTTATAAACCAAAACCACTTCCTTCTTCATC
AAGTTCGTCTCAACACAGAAATCCAGGAACAGACACGACGCCTTCTCAGAGTAACAATCAAGGTAGCAACTCTACAACGG
ATTCTTCAGATGGCAGTAGAACGTCAAGCAATGAACGAAATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(371-432)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T3DWA0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

77.015

92.982

0.716
  stkP Streptococcus pneumoniae D39

76.672

92.982

0.713
  stkP Streptococcus pneumoniae R6

76.672

92.982

0.713
  stkP Streptococcus pneumoniae Rx1

76.501

92.982

0.711
  pknB Streptococcus mutans UA159

56.11

92.663

0.52
  stkP/pknB Streptococcus salivarius strain HSISS4

51.186

94.099

0.482