Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   I6G50_RS08170 Genome accession   NZ_CP065691
Coordinates   1628892..1630109 (+) Length   405 a.a.
NCBI ID   WP_081165926.1    Uniprot ID   -
Organism   Lactococcus garvieae strain FDAARGOS_893     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1623892..1635109
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G50_RS08140 (I6G50_08135) eeP 1623906..1625153 (-) 1248 WP_197908496.1 RIP metalloprotease RseP Regulator
  I6G50_RS08145 (I6G50_08140) - 1625323..1626117 (-) 795 WP_003136056.1 phosphatidate cytidylyltransferase -
  I6G50_RS08150 (I6G50_08145) - 1626114..1626851 (-) 738 WP_003136055.1 isoprenyl transferase -
  I6G50_RS08155 (I6G50_08150) yajC 1627053..1627388 (-) 336 WP_003136054.1 preprotein translocase subunit YajC -
  I6G50_RS08160 (I6G50_08155) - 1627463..1628110 (-) 648 WP_197908498.1 DNA alkylation repair protein -
  I6G50_RS08165 (I6G50_08160) rlmH 1628107..1628586 (-) 480 WP_081165923.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6G50_RS08170 (I6G50_08165) htrA 1628892..1630109 (+) 1218 WP_081165926.1 S1C family serine protease Regulator
  I6G50_RS08175 (I6G50_08170) - 1630207..1631205 (+) 999 WP_197908500.1 glycosyltransferase -
  I6G50_RS08180 (I6G50_08175) - 1631218..1632546 (+) 1329 WP_197908502.1 glycosyltransferase family 4 protein -
  I6G50_RS08185 (I6G50_08180) - 1632601..1632825 (+) 225 WP_003136047.1 DUF1797 family protein -
  I6G50_RS08190 (I6G50_08185) - 1632859..1633908 (-) 1050 WP_197908503.1 BMP family lipoprotein -
  I6G50_RS08195 (I6G50_08190) - 1634042..1634791 (-) 750 WP_197908505.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 41668.45 Da        Isoelectric Point: 4.7934

>NTDB_id=513021 I6G50_RS08170 WP_081165926.1 1628892..1630109(+) (htrA) [Lactococcus garvieae strain FDAARGOS_893]
MAKKNIASLLITGVAGGAIALGGSAVYQSMTNTPTTTNSQNNAVSTVNVQVNTDTTKAIKTISNTVVSVLNYQKSSSSED
LDSIFGNGNRSNESSSSPQLAGEGSGVIYKKDGNTAYVVTNYHVVEGASSLEVLMAGGQKVTAEVVGSDAFSDLAVLKID
AKYVKETATFGNSDKLTVGEPAIAVGSPLGSEYANSATEGIVSSLNRNVVLQNSQGQTINVNAIQTDAAINPGNSGGALI
NIEGQVIGITSSKITSTPSGTSSSGVSVEGMGFAIPANDVVNIINKLEKDGKVIRPALGVQMVNLSSLSQNSLASLNLPE
DVTNGVAVAEVQSGMPAAKAGLKQGDVIVKINDDEITSSVNLQSTLYKSSIGDTIKVTYYRDGKKATANVKLDKTSSDIN
FDKQN

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=513021 I6G50_RS08170 WP_081165926.1 1628892..1630109(+) (htrA) [Lactococcus garvieae strain FDAARGOS_893]
ATGGCAAAAAAAAATATCGCCTCACTGCTAATCACTGGCGTAGCTGGTGGTGCTATCGCTCTAGGAGGTAGTGCTGTTTA
TCAAAGCATGACCAACACACCAACAACCACTAATAGTCAAAATAACGCTGTTAGTACGGTTAATGTACAAGTCAATACAG
ATACAACCAAAGCAATAAAAACAATTTCAAACACTGTCGTCTCTGTCCTCAACTATCAAAAGTCATCTTCAAGCGAAGAT
TTAGATAGTATCTTTGGTAATGGCAATAGAAGTAATGAAAGTTCTAGTAGTCCACAGCTGGCAGGGGAAGGATCTGGTGT
AATCTATAAAAAAGATGGCAATACAGCTTATGTTGTGACAAACTACCACGTGGTCGAAGGTGCATCTTCATTAGAGGTTC
TCATGGCGGGCGGCCAAAAAGTAACTGCCGAAGTCGTGGGATCAGACGCCTTTTCTGATTTGGCTGTCCTCAAAATTGAT
GCTAAATATGTCAAAGAGACAGCCACTTTTGGGAATTCGGATAAACTGACTGTTGGTGAACCTGCAATAGCAGTTGGTTC
TCCTCTTGGAAGTGAATATGCCAATTCTGCAACGGAAGGAATTGTTTCAAGTCTTAACCGAAATGTTGTCCTTCAAAATA
GTCAAGGCCAAACCATCAATGTCAATGCTATCCAAACAGATGCGGCCATCAATCCAGGTAACTCTGGAGGTGCCCTCATC
AATATCGAAGGACAAGTCATCGGTATCACATCAAGTAAGATTACCTCAACACCAAGTGGTACAAGTAGCAGTGGCGTGTC
TGTAGAAGGGATGGGATTCGCTATTCCTGCAAATGATGTTGTCAATATCATTAATAAACTTGAAAAAGATGGAAAAGTGA
TACGTCCTGCCTTAGGCGTTCAAATGGTCAACCTCTCAAGCCTTTCACAAAATAGTTTGGCTTCCCTTAATCTACCAGAA
GATGTCACAAATGGTGTAGCGGTTGCTGAAGTTCAATCAGGTATGCCCGCAGCCAAGGCTGGACTCAAACAAGGCGATGT
TATCGTCAAAATTAATGATGACGAAATTACTTCAAGCGTAAATCTTCAAAGTACACTTTATAAATCTTCTATCGGTGATA
CTATTAAAGTAACTTACTACCGTGATGGGAAAAAAGCTACTGCTAACGTTAAGCTTGATAAAACAAGCAGTGATATTAAC
TTCGACAAACAAAATTGA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(296-392)

Peptidase family M50 (Peptidase_M50)

(169-396)

Trypsin-like peptidase domain (Trypsin_2)

(104-249)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

54.476

96.543

0.526
  htrA Streptococcus mutans UA159

56.8

92.593

0.526
  htrA Streptococcus mitis NCTC 12261

53

98.765

0.523
  htrA Streptococcus pneumoniae TIGR4

57.101

85.185

0.486
  htrA Streptococcus pneumoniae Rx1

57.101

85.185

0.486
  htrA Streptococcus pneumoniae D39

57.101

85.185

0.486
  htrA Streptococcus pneumoniae R6

57.101

85.185

0.486