Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6G50_RS00800 Genome accession   NZ_CP065691
Coordinates   130673..131368 (+) Length   231 a.a.
NCBI ID   WP_003135047.1    Uniprot ID   K2PKE1
Organism   Lactococcus garvieae strain FDAARGOS_893     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 125673..136368
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G50_RS00770 (I6G50_00770) - 125757..126458 (+) 702 WP_003135053.1 DeoR/GlpR family DNA-binding transcription regulator -
  I6G50_RS00775 (I6G50_00775) pfkB 126455..127381 (+) 927 WP_197908877.1 1-phosphofructokinase -
  I6G50_RS00780 (I6G50_00780) - 127396..129303 (+) 1908 WP_197908878.1 PTS fructose transporter subunit IIABC -
  I6G50_RS00785 (I6G50_00785) - 129550..129792 (+) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  I6G50_RS00790 (I6G50_00790) - 129782..130039 (+) 258 WP_197908879.1 hypothetical protein -
  I6G50_RS00795 (I6G50_00795) - 130020..130571 (+) 552 WP_003135049.1 YceD family protein -
  I6G50_RS00800 (I6G50_00800) covR 130673..131368 (+) 696 WP_003135047.1 response regulator transcription factor Regulator
  I6G50_RS00805 (I6G50_00805) covS 131444..132934 (+) 1491 WP_197908880.1 HAMP domain-containing sensor histidine kinase Regulator
  I6G50_RS00810 (I6G50_00810) - 133327..134898 (+) 1572 WP_003135045.1 ABC transporter permease subunit -
  I6G50_RS00815 (I6G50_00815) - 134899..135636 (+) 738 WP_003135044.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 26996.73 Da        Isoelectric Point: 5.1203

>NTDB_id=513000 I6G50_RS00800 WP_003135047.1 130673..131368(+) (covR) [Lactococcus garvieae strain FDAARGOS_893]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQDNGRRGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDNIHIAEKADNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=513000 I6G50_RS00800 WP_003135047.1 130673..131368(+) (covR) [Lactococcus garvieae strain FDAARGOS_893]
ATGAATTCATCTAAACGTATTTTGATTATCGAAGACGATAAAAATATTGCGAGATTTGTTTCACTTGAGCTTGAGCATGA
AGGTTACCAGACTGCCGTTCAAGATAATGGTCGTAGAGGTCTTGAAGAAGCGATGTCAAAAGATTATGATTTGATTTTGC
TTGACCTGATGTTACCTGAACTTGATGGCTTCGAGGTTGCACGTCGCTTACGCCGTGAAAAAGATACTCATATTATTATG
ATGACGGCGCGTGATTCAACTATGGACCGCGTTGCTGGTCTTGATATTGGTGCTGATGACTATATTACAAAACCTTTTGC
CATCGAAGAGCTCTTGGCTCGTGTGCGTTCACTTTTCCGTCGTGAAGATAATATTCATATCGCGGAGAAGGCAGATAACA
CTTCATTCCGCGACTTGGTGATTGATAAAACAAACCGTACGGTTCATCGTGGTAAAAAGGTTATCGACCTTACACGCCGG
GAATATGACTTGCTCTTAACACTCATGCAAAATGTGGGTGACGTTGTAACACGTGAGTATTTGGTTTCAGAAGTCTGGGG
TTATGAAGAAGGAACCGAGACAAACGTTGTTGACGTTTATATTCGCTATTTGCGTAACAAAATTGATGTGGAAGGGCGTG
AGAGCTATATCCAAACCGTTCGTGGGATGGGATATGTCATGCGCGACCGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(7-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K2PKE1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

88.21

99.134

0.874
  covR Streptococcus salivarius strain HSISS4

68.122

99.134

0.675
  vicR Streptococcus mutans UA159

44.589

100

0.446
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424