Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   I6G86_RS09655 Genome accession   NZ_CP065637
Coordinates   1878648..1879343 (-) Length   231 a.a.
NCBI ID   WP_004259096.1    Uniprot ID   -
Organism   Lactococcus garvieae strain FDAARGOS_929     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1873648..1884343
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G86_RS09640 (I6G86_09645) - 1874363..1875100 (-) 738 WP_042217256.1 amino acid ABC transporter ATP-binding protein -
  I6G86_RS09645 (I6G86_09650) - 1875101..1876672 (-) 1572 WP_042217258.1 ABC transporter permease subunit -
  I6G86_RS09650 (I6G86_09655) covS 1877069..1878559 (-) 1491 WP_042217260.1 HAMP domain-containing histidine kinase Regulator
  I6G86_RS09655 (I6G86_09660) covR 1878648..1879343 (-) 696 WP_004259096.1 response regulator transcription factor Regulator
  I6G86_RS09660 (I6G86_09665) - 1879445..1879996 (-) 552 WP_023889673.1 DUF177 domain-containing protein -
  I6G86_RS09665 (I6G86_09670) - 1880213..1880455 (-) 243 WP_003135050.1 type B 50S ribosomal protein L31 -
  I6G86_RS09670 (I6G86_09675) - 1880567..1882471 (-) 1905 WP_014024348.1 fructose-specific PTS transporter subunit EIIC -
  I6G86_RS09675 (I6G86_09680) pfkB 1882486..1883412 (-) 927 WP_042217267.1 1-phosphofructokinase -
  I6G86_RS09680 (I6G86_09685) - 1883409..1884110 (-) 702 WP_004259114.1 DeoR/GlpR family DNA-binding transcription regulator -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 26979.74 Da        Isoelectric Point: 5.4730

>NTDB_id=512410 I6G86_RS09655 WP_004259096.1 1878648..1879343(-) (covR) [Lactococcus garvieae strain FDAARGOS_929]
MNSSKRILIIEDDKNIARFVSLELEHEGYQTAVQGNGRKGLEEAMSKDYDLILLDLMLPELDGFEVARRLRREKDTHIIM
MTARDSTMDRVAGLDIGADDYITKPFAIEELLARVRSLFRREDHIHTIEKSDNTSFRDLVIDKTNRTVHRGKKVIDLTRR
EYDLLLTLMQNVGDVVTREYLVSEVWGYEEGTETNVVDVYIRYLRNKIDVEGRESYIQTVRGMGYVMRDRK

Nucleotide


Download         Length: 696 bp        

>NTDB_id=512410 I6G86_RS09655 WP_004259096.1 1878648..1879343(-) (covR) [Lactococcus garvieae strain FDAARGOS_929]
ATGAATTCATCTAAACGTATTTTGATTATCGAAGACGATAAAAACATTGCGAGATTTGTTTCACTTGAGCTTGAACACGA
AGGATACCAAACTGCGGTTCAAGGCAATGGTCGTAAAGGTCTTGAAGAAGCAATGTCAAAAGATTATGATTTGATTTTGC
TTGACTTAATGCTCCCAGAGCTTGATGGCTTTGAGGTTGCACGACGCTTACGCCGTGAGAAAGATACACATATTATTATG
ATGACTGCACGTGATTCGACAATGGACCGTGTAGCAGGTCTTGATATTGGCGCAGATGACTATATTACAAAACCATTTGC
TATTGAAGAATTGTTAGCGCGTGTCCGCTCACTCTTCCGTCGTGAAGATCATATCCACACGATTGAAAAGTCCGACAATA
CTTCATTCCGTGATTTGGTAATTGATAAGACCAACCGTACTGTACACCGTGGAAAAAAAGTTATTGACCTTACACGCCGT
GAGTACGATTTGCTTTTGACACTGATGCAAAATGTAGGTGATGTCGTAACACGTGAATACTTGGTTTCTGAAGTATGGGG
TTACGAAGAAGGTACAGAAACAAACGTTGTGGACGTTTATATCCGTTATCTGCGTAACAAAATTGACGTGGAGGGCCGTG
AAAGCTATATCCAAACGGTTCGTGGTATGGGATATGTCATGCGTGACCGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(7-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

87.773

99.134

0.87
  covR Streptococcus salivarius strain HSISS4

66.81

100

0.671
  vicR Streptococcus mutans UA159

43.723

100

0.437
  micA Streptococcus pneumoniae Cp1015

42.424

100

0.424