Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   I6G86_RS02665 Genome accession   NZ_CP065637
Coordinates   473928..475145 (-) Length   405 a.a.
NCBI ID   WP_042219629.1    Uniprot ID   -
Organism   Lactococcus garvieae strain FDAARGOS_929     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 468928..480145
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G86_RS02640 (I6G86_02640) - 469226..469975 (+) 750 WP_019298937.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  I6G86_RS02645 (I6G86_02645) - 470134..471183 (+) 1050 WP_042219635.1 BMP family protein -
  I6G86_RS02650 (I6G86_02650) - 471210..471434 (-) 225 WP_003133519.1 DUF1797 family protein -
  I6G86_RS02655 (I6G86_02655) - 471485..472819 (-) 1335 WP_042219632.1 glycosyltransferase family 4 protein -
  I6G86_RS02660 (I6G86_02660) - 472832..473830 (-) 999 WP_042219630.1 glycosyltransferase family 4 protein -
  I6G86_RS02665 (I6G86_02665) htrA 473928..475145 (-) 1218 WP_042219629.1 S1C family serine protease Regulator
  I6G86_RS02670 (I6G86_02670) rlmH 475449..475928 (+) 480 WP_003133515.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6G86_RS02675 (I6G86_02675) - 475925..476572 (+) 648 WP_042219626.1 DNA alkylation repair protein -
  I6G86_RS02680 (I6G86_02680) yajC 476647..476982 (+) 336 WP_042219624.1 preprotein translocase subunit YajC -
  I6G86_RS02685 (I6G86_02685) - 477183..477920 (+) 738 WP_003133511.1 isoprenyl transferase -
  I6G86_RS02690 (I6G86_02690) - 477917..478711 (+) 795 WP_003133509.1 phosphatidate cytidylyltransferase -
  I6G86_RS02695 (I6G86_02695) eeP 478887..480134 (+) 1248 WP_014025467.1 RIP metalloprotease RseP Regulator

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 41785.67 Da        Isoelectric Point: 4.8808

>NTDB_id=512393 I6G86_RS02665 WP_042219629.1 473928..475145(-) (htrA) [Lactococcus garvieae strain FDAARGOS_929]
MAKKNIASLLITGVAGGAIALGGSAIYQNMTNTPSSNNTSDNSVSTVNVQVNTDTTKAIKKISNTVVSVLNYQKSSSSND
FEKILGGGDTSSNDSNTPQLAGEGSGVIYKKDGNTAYIVTNYHVIEGASSLEVLMAGGQKVTAEVVGSDAYSDLAVLKID
AKYVKETATFGNSDKLTVGEPAIAVGSPLGSEYANSATEGIVSSLNRNVTLQNSQGQTINVNAIQTDAAINPGNSGGALI
NIQGQVIGITSSKITSTPSGTSGSGVSVEGMGFAIPANDVVNIINKLEKDGKVIRPALGVQMVNLSSLSQNMLASLNLPE
NVTNGVAIAEVQSGMPAAKAGLKQGDVIVKINDDEITSSMNLQSTLYKSSIGDTIKVTYYRDGKQATANIKLDKTSSDIN
FDKQN

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=512393 I6G86_RS02665 WP_042219629.1 473928..475145(-) (htrA) [Lactococcus garvieae strain FDAARGOS_929]
ATGGCAAAGAAAAATATCGCCTCATTACTTATTACGGGCGTAGCCGGAGGTGCTATCGCTCTTGGAGGTAGTGCTATCTA
CCAAAACATGACCAACACACCATCATCTAATAACACTTCGGACAATTCTGTAAGTACGGTTAACGTCCAAGTCAATACAG
ATACCACCAAAGCAATCAAGAAAATTTCGAACACTGTTGTTTCCGTTCTTAATTACCAAAAATCGTCCTCAAGCAACGAT
TTTGAGAAGATTTTAGGTGGAGGCGATACAAGCAGCAATGACAGTAACACGCCACAGCTGGCTGGTGAAGGTTCTGGTGT
TATTTATAAAAAGGATGGCAATACAGCATACATCGTCACCAACTATCACGTGATTGAAGGTGCTTCTTCCTTAGAAGTTC
TCATGGCTGGCGGCCAAAAAGTTACTGCTGAAGTTGTTGGTTCTGATGCTTATTCTGATTTAGCTGTCCTCAAAATTGAT
GCTAAGTATGTCAAAGAAACAGCAACATTCGGTAACTCTGACAAACTTACTGTTGGTGAGCCCGCTATCGCGGTTGGTTC
TCCTCTTGGAAGTGAGTATGCCAACTCAGCAACGGAAGGGATTGTTTCAAGTCTTAATCGTAATGTTACGCTGCAAAACA
GCCAAGGCCAAACAATTAATGTGAACGCAATTCAAACCGATGCAGCAATTAACCCAGGTAACTCTGGTGGTGCACTCATA
AATATTCAGGGACAAGTCATCGGTATTACTTCAAGTAAAATTACCTCAACACCAAGCGGAACAAGCGGCAGTGGTGTTTC
TGTAGAAGGAATGGGCTTTGCGATACCAGCCAATGATGTGGTCAATATTATCAATAAGTTGGAAAAAGATGGCAAAGTTA
TTCGACCTGCTCTCGGTGTACAAATGGTCAACTTGTCAAGTCTTTCACAAAATATGTTGGCTTCACTTAATCTTCCTGAA
AATGTGACAAATGGTGTTGCTATCGCTGAAGTTCAATCAGGAATGCCTGCTGCCAAAGCTGGACTCAAGCAAGGTGACGT
TATTGTCAAAATCAATGATGACGAAATCACTTCAAGTATGAACCTTCAAAGTACACTTTATAAGTCATCGATTGGTGATA
CGATTAAGGTAACTTATTATCGTGACGGAAAACAAGCTACTGCAAATATCAAGTTGGATAAGACAAGTAGTGACATCAAC
TTTGACAAACAAAATTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(296-392)

Peptidase family M50 (Peptidase_M50)

(294-396)

Trypsin-like peptidase domain (Trypsin_2)

(104-249)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

53.383

98.519

0.526
  htrA Streptococcus pneumoniae Rx1

53.133

98.519

0.523
  htrA Streptococcus pneumoniae D39

53.133

98.519

0.523
  htrA Streptococcus pneumoniae R6

53.133

98.519

0.523
  htrA Streptococcus pneumoniae TIGR4

53.133

98.519

0.523
  htrA Streptococcus gordonii str. Challis substr. CH1

54.22

96.543

0.523
  htrA Streptococcus mutans UA159

56.15

92.346

0.519