Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   STCNRZ1202_RS01655 Genome accession   NZ_CP065506
Coordinates   301690..302379 (+) Length   229 a.a.
NCBI ID   WP_014607969.1    Uniprot ID   A0A2H4K9N5
Organism   Streptococcus thermophilus strain CNRZ1202     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 296690..307379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STCNRZ1202_RS01630 - 297701..297826 (+) 126 Protein_268 ascorbate 6-phosphate lactonase -
  STCNRZ1202_RS01635 (STCNRZ1202_01660) - 297843..298514 (-) 672 WP_002946492.1 TrkA family potassium uptake protein -
  STCNRZ1202_RS01640 (STCNRZ1202_01665) - 298554..299918 (-) 1365 WP_347229670.1 potassium transporter TrkG -
  STCNRZ1202_RS01645 (STCNRZ1202_01670) rsmG 299988..300701 (-) 714 WP_002949634.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  STCNRZ1202_RS01650 (STCNRZ1202_01675) - 300998..301534 (+) 537 WP_065972912.1 YceD family protein -
  STCNRZ1202_RS01655 (STCNRZ1202_01680) covR 301690..302379 (+) 690 WP_014607969.1 response regulator transcription factor Regulator
  STCNRZ1202_RS01660 (STCNRZ1202_01685) covS 302376..303893 (+) 1518 WP_347229671.1 HAMP domain-containing histidine kinase Regulator
  STCNRZ1202_RS01665 (STCNRZ1202_01690) nrdR 304015..304494 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  STCNRZ1202_RS01670 (STCNRZ1202_01695) - 304491..305666 (+) 1176 WP_002949643.1 DnaD domain protein -
  STCNRZ1202_RS01675 (STCNRZ1202_01700) dnaI 305670..306572 (+) 903 WP_002946786.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26637.73 Da        Isoelectric Point: 4.7059

>NTDB_id=511362 STCNRZ1202_RS01655 WP_014607969.1 301690..302379(+) (covR) [Streptococcus thermophilus strain CNRZ1202]
MSKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLELALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIIKPFAIEELLARIRATFRRQDIEATKKAPAKASTYRDLKLDVQNRAVVRGDEVIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIRER

Nucleotide


Download         Length: 690 bp        

>NTDB_id=511362 STCNRZ1202_RS01655 WP_014607969.1 301690..302379(+) (covR) [Streptococcus thermophilus strain CNRZ1202]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCGGACAACGGACGCGAAGGACTTGAATTGGCACTTGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTCGAAGTGACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCTGGTTTGGATCGTGGAGCTGATGACTATATTATAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACCTTCCGTCGTCAAGATATCGAAGCTACTAAGAAGGCACCAGCTAAAGCGTCAA
CCTATCGCGATTTAAAATTGGATGTTCAAAACCGTGCAGTTGTTCGCGGTGATGAGGTAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAGCAATATGAACCAAGTAATGACCCGTGAGGAACTCTTGCTTCAAGTCTGGAAATA
TGATGACGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATACATTCAAACAGTACGAGGGATGGGTTACGTTATCCGTGAAAGATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2H4K9N5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

95.633

100

0.956
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.544

99.563

0.672
  vicR Streptococcus mutans UA159

45.259

100

0.459
  micA Streptococcus pneumoniae Cp1015

43.913

100

0.441