Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   STCNRZ1202_RS01660 Genome accession   NZ_CP065506
Coordinates   302376..303893 (+) Length   505 a.a.
NCBI ID   WP_347229671.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CNRZ1202     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 297376..308893
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STCNRZ1202_RS01630 - 297701..297826 (+) 126 Protein_268 ascorbate 6-phosphate lactonase -
  STCNRZ1202_RS01635 (STCNRZ1202_01660) - 297843..298514 (-) 672 WP_002946492.1 TrkA family potassium uptake protein -
  STCNRZ1202_RS01640 (STCNRZ1202_01665) - 298554..299918 (-) 1365 WP_347229670.1 potassium transporter TrkG -
  STCNRZ1202_RS01645 (STCNRZ1202_01670) rsmG 299988..300701 (-) 714 WP_002949634.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  STCNRZ1202_RS01650 (STCNRZ1202_01675) - 300998..301534 (+) 537 WP_065972912.1 YceD family protein -
  STCNRZ1202_RS01655 (STCNRZ1202_01680) covR 301690..302379 (+) 690 WP_014607969.1 response regulator transcription factor Regulator
  STCNRZ1202_RS01660 (STCNRZ1202_01685) covS 302376..303893 (+) 1518 WP_347229671.1 HAMP domain-containing histidine kinase Regulator
  STCNRZ1202_RS01665 (STCNRZ1202_01690) nrdR 304015..304494 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  STCNRZ1202_RS01670 (STCNRZ1202_01695) - 304491..305666 (+) 1176 WP_002949643.1 DnaD domain protein -
  STCNRZ1202_RS01675 (STCNRZ1202_01700) dnaI 305670..306572 (+) 903 WP_002946786.1 primosomal protein DnaI -
  STCNRZ1202_RS01680 (STCNRZ1202_01705) der 306678..307988 (+) 1311 WP_002946789.1 ribosome biogenesis GTPase Der -
  STCNRZ1202_RS01685 (STCNRZ1202_01710) - 308052..308721 (+) 670 Protein_279 HI_0552 family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57522.90 Da        Isoelectric Point: 5.2689

>NTDB_id=511363 STCNRZ1202_RS01660 WP_347229671.1 302376..303893(+) (covS) [Streptococcus thermophilus strain CNRZ1202]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLEFYYALKERLIFLLIFLEVGMTVLVIAVSVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQITIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=511363 STCNRZ1202_RS01660 WP_347229671.1 302376..303893(+) (covS) [Streptococcus thermophilus strain CNRZ1202]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCCTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAGCTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAAGTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACGATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGCTTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAATCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTTCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGATTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

ArlS sensor domain (ArlS_N)

(39-187)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.422

99.406

0.939