Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   STT55_RS01015 Genome accession   NZ_CP065502
Coordinates   172976..173725 (+) Length   249 a.a.
NCBI ID   WP_173940587.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST55     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 167976..178725
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STT55_RS00985 (STT55_00975) - 168550..168720 (+) 171 WP_172838670.1 hypothetical protein -
  STT55_RS00990 (STT55_00980) - 168807..168914 (+) 108 WP_084829946.1 LPXTG cell wall anchor domain-containing protein -
  STT55_RS00995 (STT55_00985) - 169002..169742 (-) 741 WP_002949253.1 amino acid ABC transporter ATP-binding protein -
  STT55_RS01000 (STT55_00990) - 169742..171292 (-) 1551 WP_347229931.1 ABC transporter substrate-binding protein/permease -
  STT55_RS01005 (STT55_00995) - 171495..172349 (+) 855 WP_041828107.1 undecaprenyl-diphosphate phosphatase -
  STT55_RS01010 (STT55_01000) - 172495..172710 (-) 216 WP_011226805.1 DUF3021 family protein -
  STT55_RS01015 (STT55_01005) mecA 172976..173725 (+) 750 WP_173940587.1 adaptor protein MecA Regulator
  STT55_RS01020 (STT55_01010) - 173729..174886 (+) 1158 WP_002947632.1 MraY family glycosyltransferase -
  STT55_RS01025 (STT55_01015) sufC 175047..175817 (+) 771 WP_002947634.1 Fe-S cluster assembly ATPase SufC -
  STT55_RS01030 (STT55_01020) sufD 175854..177116 (+) 1263 WP_173940586.1 Fe-S cluster assembly protein SufD -
  STT55_RS01035 (STT55_01025) - 177170..178402 (+) 1233 WP_173940585.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29156.71 Da        Isoelectric Point: 4.0844

>NTDB_id=511232 STT55_RS01015 WP_173940587.1 172976..173725(+) (mecA) [Streptococcus thermophilus strain ST55]
MEMKQINETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEALDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSEFYKLGDVYYMTILLYLADEPNYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=511232 STT55_RS01015 WP_173940587.1 172976..173725(+) (mecA) [Streptococcus thermophilus strain ST55]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGCCCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGAGCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAATTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTAATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMG 18311

99.598

100

0.996
  mecA Streptococcus thermophilus LMD-9

98.795

100

0.988
  mecA Streptococcus mutans UA159

56.967

97.992

0.558
  mecA Streptococcus pneumoniae Rx1

46.185

100

0.462
  mecA Streptococcus pneumoniae D39

46.185

100

0.462
  mecA Streptococcus pneumoniae R6

46.185

100

0.462
  mecA Streptococcus pneumoniae TIGR4

46.185

100

0.462