Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   STT128_RS01755 Genome accession   NZ_CP065500
Coordinates   311628..312317 (+) Length   229 a.a.
NCBI ID   WP_347230108.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST128     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 306628..317317
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STT128_RS01730 - 307594..307764 (+) 171 Protein_288 ascorbate 6-phosphate lactonase -
  STT128_RS01735 (STT128_01760) - 307781..308452 (-) 672 WP_002946492.1 TrkA family potassium uptake protein -
  STT128_RS01740 (STT128_01765) - 308492..309856 (-) 1365 WP_347230107.1 potassium transporter TrkG -
  STT128_RS01745 (STT128_01770) rsmG 309926..310639 (-) 714 WP_002949634.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  STT128_RS01750 (STT128_01775) - 310936..311472 (+) 537 WP_065972912.1 YceD family protein -
  STT128_RS01755 (STT128_01780) covR 311628..312317 (+) 690 WP_347230108.1 response regulator transcription factor Regulator
  STT128_RS01760 (STT128_01785) covS 312314..313831 (+) 1518 WP_347230109.1 HAMP domain-containing histidine kinase Regulator
  STT128_RS01765 (STT128_01790) nrdR 313953..314432 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  STT128_RS01770 (STT128_01795) - 314429..315604 (+) 1176 WP_180474498.1 DnaD domain protein -
  STT128_RS01775 (STT128_01800) dnaI 315608..316510 (+) 903 WP_084828487.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26692.83 Da        Isoelectric Point: 4.7834

>NTDB_id=511181 STT128_RS01755 WP_347230108.1 311628..312317(+) (covR) [Streptococcus thermophilus strain ST128]
MSKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIIKPFAIEELLARIRATFRRQDIEATKKVPAKASTYRDLKLDVQNRAVVRGDEVIPLTKRE
FDLLNTLLSNMNHVMTREELLLQVWKYDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIRER

Nucleotide


Download         Length: 690 bp        

>NTDB_id=511181 STT128_RS01755 WP_347230108.1 311628..312317(+) (covR) [Streptococcus thermophilus strain ST128]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCGGACAACGGACGCGAAGGACTTGAAATGGCACTTGAGAAAGATTTCGATCTGATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTCGAAGTGACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCTGGTTTGGATCGTGGAGCTGATGACTATATTATAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACCTTCCGTCGTCAAGATATCGAAGCTACTAAGAAGGTACCAGCTAAAGCGTCAA
CCTATCGCGATTTAAAATTGGATGTTCAAAACCGTGCAGTTGTTCGCGGTGATGAGGTAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAGCAATATGAACCACGTAATGACCCGTGAGGAACTCTTGCTTCAAGTCTGGAAATA
TGATGACGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATACATTCAAACAGTACGAGGGATGGGTTACGTTATCCGTGAAAGATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

95.197

100

0.952
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.544

99.563

0.672
  vicR Streptococcus mutans UA159

44.397

100

0.45
  micA Streptococcus pneumoniae Cp1015

41.667

100

0.437