Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   STT128_RS01760 Genome accession   NZ_CP065500
Coordinates   312314..313831 (+) Length   505 a.a.
NCBI ID   WP_347230109.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST128     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 307314..318831
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STT128_RS01730 - 307594..307764 (+) 171 Protein_288 ascorbate 6-phosphate lactonase -
  STT128_RS01735 (STT128_01760) - 307781..308452 (-) 672 WP_002946492.1 TrkA family potassium uptake protein -
  STT128_RS01740 (STT128_01765) - 308492..309856 (-) 1365 WP_347230107.1 potassium transporter TrkG -
  STT128_RS01745 (STT128_01770) rsmG 309926..310639 (-) 714 WP_002949634.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  STT128_RS01750 (STT128_01775) - 310936..311472 (+) 537 WP_065972912.1 YceD family protein -
  STT128_RS01755 (STT128_01780) covR 311628..312317 (+) 690 WP_347230108.1 response regulator transcription factor Regulator
  STT128_RS01760 (STT128_01785) covS 312314..313831 (+) 1518 WP_347230109.1 HAMP domain-containing histidine kinase Regulator
  STT128_RS01765 (STT128_01790) nrdR 313953..314432 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  STT128_RS01770 (STT128_01795) - 314429..315604 (+) 1176 WP_180474498.1 DnaD domain protein -
  STT128_RS01775 (STT128_01800) dnaI 315608..316510 (+) 903 WP_084828487.1 primosomal protein DnaI -
  STT128_RS01780 (STT128_01805) der 316616..317926 (+) 1311 WP_347230110.1 ribosome biogenesis GTPase Der -
  STT128_RS01785 (STT128_01810) - 317990..318658 (+) 669 Protein_299 HI_0552 family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57572.02 Da        Isoelectric Point: 5.5179

>NTDB_id=511182 STT128_RS01760 WP_347230109.1 312314..313831(+) (covS) [Streptococcus thermophilus strain ST128]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSSEPLLAAFY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLKFYYALKERLIFLLIFLEVGMTVLVIAVIVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQITIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=511182 STT128_RS01760 WP_347230109.1 312314..313831(+) (covS) [Streptococcus thermophilus strain ST128]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTTCAGAGCCGCTTTTAGCGGCCTTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGAAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAATTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACAATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGCTTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTCCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGATTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

ArlS sensor domain (ArlS_N)

(39-187)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

93.825

99.406

0.933