Detailed information NTG0511102

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: ST4067_RS08750
• Genome accession: NZ_CP065496
• Coordinates: 1682446..1682883 (-)
• Length: 145 a.a.
• NCBI ID: WP_263604537.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4067
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1677446..1687883

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4067_RS08715 (ST4067_08730)	-	1677505..1678167 (-)	663	WP_011227583.1	CPBP family intramembrane glutamic endopeptidase	-
ST4067_RS08720 (ST4067_08735)	-	1678270..1678713 (-)	444	WP_011681680.1	hypothetical protein	-
ST4067_RS08725	-	1678787..1679212 (-)	426	WP_263604536.1	CPBP family intramembrane glutamic endopeptidase	-
ST4067_RS08730 (ST4067_08745)	-	1679455..1679652 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
ST4067_RS08735 (ST4067_08750)	-	1679901..1681094 (-)	1194	WP_014608740.1	acetate kinase	-
ST4067_RS08740 (ST4067_08755)	comYH	1681150..1682106 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
ST4067_RS08745 (ST4067_08760)	comGG	1682151..1682468 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
ST4067_RS08750 (ST4067_08765)	comYF	1682446..1682883 (-)	438	WP_263604537.1	competence type IV pilus minor pilin ComGF	Machinery gene
ST4067_RS08755 (ST4067_08770)	comGE	1682867..1683160 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
ST4067_RS08760 (ST4067_08775)	comYD	1683132..1683560 (-)	429	WP_263604538.1	competence type IV pilus minor pilin ComGD	Machinery gene
ST4067_RS08765 (ST4067_08780)	comYC	1683520..1683846 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
ST4067_RS08770 (ST4067_08785)	comYB	1683843..1684943 (-)	1101	WP_148148900.1	competence type IV pilus assembly protein ComGB	Machinery gene
ST4067_RS08775 (ST4067_08790)	comGA/cglA/cilD	1684825..1685766 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
ST4067_RS08780 (ST4067_08795)	-	1685847..1686209 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16549.06 Da
• Isoelectric Point: 8.4474

>NTDB_id=511102 ST4067_RS08750 WP_263604537.1 1682446..1682883(-) (comYF) [Streptococcus thermophilus strain 4067]
MYLSSKLRAFTLLECLVALLVIDGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEWNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=511102 ST4067_RS08750 WP_263604537.1 1682446..1682883(-) (comYF) [Streptococcus thermophilus strain 4067]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGATGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGTGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.156	97.241	0.566
comYF	Streptococcus mutans UA159	57.447	97.241	0.559
comGF/cglF	Streptococcus pneumoniae D39	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae Rx1	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae R6	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae TIGR4	47.857	96.552	0.462
comGF/cglF	Streptococcus mitis NCTC 12261	46.099	97.241	0.448
comGF/cglF	Streptococcus mitis SK321	45.39	97.241	0.441
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441