Detailed information NTG0511105

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: ST4067_RS08770
• Genome accession: NZ_CP065496
• Coordinates: 1683843..1684943 (-)
• Length: 366 a.a.
• NCBI ID: WP_148148900.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4067
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1678843..1689943

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4067_RS08730 (ST4067_08745)	-	1679455..1679652 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
ST4067_RS08735 (ST4067_08750)	-	1679901..1681094 (-)	1194	WP_014608740.1	acetate kinase	-
ST4067_RS08740 (ST4067_08755)	comYH	1681150..1682106 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
ST4067_RS08745 (ST4067_08760)	comGG	1682151..1682468 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
ST4067_RS08750 (ST4067_08765)	comYF	1682446..1682883 (-)	438	WP_263604537.1	competence type IV pilus minor pilin ComGF	Machinery gene
ST4067_RS08755 (ST4067_08770)	comGE	1682867..1683160 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
ST4067_RS08760 (ST4067_08775)	comYD	1683132..1683560 (-)	429	WP_263604538.1	competence type IV pilus minor pilin ComGD	Machinery gene
ST4067_RS08765 (ST4067_08780)	comYC	1683520..1683846 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
ST4067_RS08770 (ST4067_08785)	comYB	1683843..1684943 (-)	1101	WP_148148900.1	competence type IV pilus assembly protein ComGB	Machinery gene
ST4067_RS08775 (ST4067_08790)	comGA/cglA/cilD	1684825..1685766 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
ST4067_RS08780 (ST4067_08795)	-	1685847..1686209 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41754.88 Da
• Isoelectric Point: 10.0449

>NTDB_id=511105 ST4067_RS08770 WP_148148900.1 1683843..1684943(-) (comYB) [Streptococcus thermophilus strain 4067]
MPEKISKTIRLPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=511105 ST4067_RS08770 WP_148148900.1 1683843..1684943(-) (comYB) [Streptococcus thermophilus strain 4067]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCTACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCAGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.394	90.164	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413