Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   ST4067_RS06550 Genome accession   NZ_CP065496
Coordinates   1252721..1254592 (-) Length   623 a.a.
NCBI ID   WP_263604432.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4067     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1247721..1259592
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4067_RS06515 (ST4067_06540) rimM 1248133..1248651 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  ST4067_RS06530 (ST4067_06555) - 1249323..1249967 (-) 645 WP_002951384.1 response regulator transcription factor -
  ST4067_RS06535 (ST4067_06560) - 1249957..1250967 (-) 1011 WP_011226288.1 sensor histidine kinase -
  ST4067_RS06540 (ST4067_06565) liaF 1250964..1251662 (-) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  ST4067_RS06545 - 1251917..1252084 (-) 168 WP_014608530.1 potassium channel family protein -
  ST4067_RS06550 (ST4067_06575) stkP/pknB 1252721..1254592 (-) 1872 WP_263604432.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ST4067_RS06555 (ST4067_06580) - 1254592..1255329 (-) 738 WP_002946881.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ST4067_RS06560 (ST4067_06585) rsmB 1255373..1256695 (-) 1323 WP_014608533.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  ST4067_RS06565 (ST4067_06590) fmt 1256685..1257620 (-) 936 WP_002951411.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 67871.71 Da        Isoelectric Point: 6.9480

>NTDB_id=511085 ST4067_RS06550 WP_263604432.1 1252721..1254592(-) (stkP/pknB) [Streptococcus thermophilus strain 4067]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNESVAIKVLRTNYQTDQVAVARFQREARAMTELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKFIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGRAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPFDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHSRDSKVVFDDMTDAKTLPKVDSVSSVGPEKKISPKPSEPTPAP
SKQPREKASLSKKKKNLFSTLLKVLLGFVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKLESAGFKVGDVKEVEND
SVNKGKVIKTDPTAGTMRKEGASIDVYVSSGSKGFTLKNYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEGDNVKEGEILS
QSSEKNKSFNPKDSKAKIKFRVATPKTITMPDVTGLTVSTAVQTLNSKDISSSSIEYHDYNTGVKLDKSKVPSNTEVLYQ
DPQVGTAVDGTVILYVSVVTKSSSIQQSSSASTTQSPSSTSSSSESSTASSTETDTEATHTEQ

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=511085 ST4067_RS06550 WP_263604432.1 1252721..1254592(-) (stkP/pknB) [Streptococcus thermophilus strain 4067]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGTGTAGCTATTAAGGTGCTACGTACCAATTATCAAACTGATCAGGTTG
CTGTGGCGCGTTTCCAGCGTGAAGCACGTGCCATGACTGAGCTTAGCCATCCGAATATCGTTGCGATTAGAGATATTGGT
GAAGAAGACGGTCAGCAGTTCTTGGTGATGGAGTATGTGGATGGTTCGGACTTGAAGAAATTCATTCAAGACCATGCACC
ATTGTCTAACCAAGATGTTGTGCGTATTATGGGGGAAGTCCTTTCCGCCATGACTCTTGCCCACCAAAAGGGTATTATTC
ACCGTGACCTTAAGCCACAGAACGTTCTATTAACTAAGGATGGTAGAGCTAAGGTTACAGACTTTGGTATCGCAGTAGCA
TTTGCTGAAACCAGCCTGACACAAACTAACTCAATGTTGGGGTCAGTCCATTATTTGTCACCAGAACAGGCACGTGGTTC
TAAAGCCACTATCCAAAGTGATATCTATGCTATGGGGATTATGCTCTTTGAAATGTTGACAGGGCATATCCCTTTTGATG
GCGATAGTGCAGTAACCATTGCACTTCAACATTTCCAAAAGCCCCTGCCATCGATTTTGGCTGAGAACCGTAACGTTCCT
CAAGCTTTAGAAAATGTTGTTATTAGAGCAACTGCTAAAAAGCTTGAAAATCGTTACAACAGCACTTTGGAAATGAGTCG
CGACCTAGTAACTAGTTTGCATCCTAGTCATAGTCGTGATTCTAAGGTAGTTTTTGATGACATGACGGATGCTAAGACCC
TGCCAAAGGTTGATTCAGTTTCATCAGTAGGTCCTGAGAAAAAGATTTCTCCTAAACCATCAGAGCCTACACCGGCTCCA
AGCAAACAACCGAGGGAAAAAGCTTCTCTATCTAAAAAAAAGAAAAATCTCTTTTCAACTCTACTCAAGGTTTTACTAGG
CTTCGTCTTTATAGGAATTATCATTTTTGCCTATCTTGTTTTTACCAATCCTGACAATGTCCAAGTACCAAATGTTGTAG
GTCAAGAGTTGTCAACAGCTCAGACGAAACTTGAAAGTGCAGGCTTTAAGGTTGGCGATGTTAAAGAAGTCGAAAATGAT
TCAGTCAATAAGGGCAAAGTTATCAAGACCGACCCTACAGCTGGGACAATGCGTAAAGAGGGAGCAAGCATTGATGTCTA
TGTTTCTTCTGGTAGCAAAGGTTTCACTCTGAAAAATTACAAGGGGAAAAATTATAAGGATGCCATTGAGGATTTAACCT
CGAATTATGGGGTTTCCGAGGATCAGATCGATATTCAACATGTCGAAGGCGATAATGTTAAAGAAGGCGAAATTCTATCT
CAAAGTTCGGAGAAAAACAAGTCCTTCAATCCTAAAGATAGTAAGGCAAAAATCAAGTTTCGTGTGGCAACTCCTAAGAC
TATAACTATGCCTGATGTGACTGGTTTAACTGTCTCGACAGCAGTCCAAACCTTGAATAGTAAAGACATTTCAAGTAGCA
GTATTGAGTATCATGACTATAATACTGGTGTTAAGTTGGATAAGAGTAAGGTACCTAGTAATACAGAGGTCCTTTATCAA
GATCCTCAAGTTGGTACTGCTGTTGATGGCACAGTGATTCTCTATGTTTCAGTCGTAACTAAGAGTTCAAGTATTCAACA
GTCAAGCTCAGCAAGTACGACACAATCGCCGTCATCTACAAGTTCTAGTTCTGAAAGTAGTACAGCTTCTAGTACCGAAA
CAGATACAGAAGCTACTCACACAGAGCAATAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(508-577)

PASTA domain (PASTA)

(436-502)

PASTA domain (PASTA)

(367-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

90.189

93.258

0.841
  pknB Streptococcus mutans UA159

64.522

87.319

0.563
  stkP Streptococcus pneumoniae TIGR4

56.713

80.096

0.454
  stkP Streptococcus pneumoniae D39

56.513

80.096

0.453
  stkP Streptococcus pneumoniae R6

56.513

80.096

0.453
  stkP Streptococcus pneumoniae Rx1

56.313

80.096

0.451