Detailed information NTG0510989

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: ST4021_RS09640
• Genome accession: NZ_CP065493
• Coordinates: 1859415..1860650 (+)
• Length: 411 a.a.
• NCBI ID: WP_011681767.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4021
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1854415..1865650

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4021_RS09610 (ST4021_09685)	-	1854882..1857488 (+)	2607	WP_024704279.1	YfhO family protein	-
ST4021_RS09630 (ST4021_09705)	-	1858032..1858715 (-)	684	WP_011226711.1	YoaK family protein	-
ST4021_RS09635 (ST4021_09710)	rlmH	1858731..1859210 (-)	480	WP_011681766.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
ST4021_RS09640 (ST4021_09715)	htrA	1859415..1860650 (+)	1236	WP_011681767.1	trypsin-like peptidase domain-containing protein	Regulator
ST4021_RS09645 (ST4021_09720)	spo0J	1860716..1861483 (+)	768	WP_011681768.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42797.07 Da
• Isoelectric Point: 4.7061

>NTDB_id=510989 ST4021_RS09640 WP_011681767.1 1859415..1860650(+) (htrA) [Streptococcus thermophilus strain 4021]
MKKINWKKIVAPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDTGAKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=510989 ST4021_RS09640 WP_011681767.1 1859415..1860650(+) (htrA) [Streptococcus thermophilus strain 4021]
ATGAAAAAAATTAACTGGAAGAAAATAGTCGCGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGCAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGCCTGCAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCACGTTGTCGATGGGGCTAAAAAACTCGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATTGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (307-402)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• Peptidase family M50 (Peptidase_M50) (46-406)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.538	98.054	0.603
htrA	Streptococcus gordonii str. Challis substr. CH1	57.389	98.783	0.567
htrA	Streptococcus mitis NCTC 12261	53.808	99.027	0.533
htrA	Streptococcus pneumoniae TIGR4	53.563	99.027	0.53
htrA	Streptococcus pneumoniae D39	53.563	99.027	0.53
htrA	Streptococcus pneumoniae Rx1	53.563	99.027	0.53
htrA	Streptococcus pneumoniae R6	53.563	99.027	0.53