Detailed information NTG0510978

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ST4021_RS08000
• Genome accession: NZ_CP065493
• Coordinates: 1547587..1549740 (-)
• Length: 717 a.a.
• NCBI ID: WP_041827772.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4021
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1542587..1554740

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4021_RS07965 (ST4021_07995)	-	1542707..1542937 (-)	231	WP_011226494.1	bacteriocin class II family protein	-
ST4021_RS07970 (ST4021_08000)	-	1543293..1543493 (-)	201	WP_011681569.1	hypothetical protein	-
ST4021_RS07975 (ST4021_08005)	-	1543512..1543688 (-)	177	WP_011681570.1	Blp family class II bacteriocin	-
ST4021_RS07980 (ST4021_08010)	-	1543939..1544676 (+)	738	WP_011681571.1	response regulator transcription factor	-
ST4021_RS07985	-	1545207..1546010 (+)	804	WP_223899638.1	ATP-binding protein	-
ST4021_RS07990 (ST4021_08020)	-	1546028..1546189 (-)	162	WP_011681573.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
ST4021_RS07995 (ST4021_08025)	-	1546204..1547571 (-)	1368	WP_011681574.1	bacteriocin secretion accessory protein	-
ST4021_RS08000 (ST4021_08030)	comA/nlmT	1547587..1549740 (-)	2154	WP_041827772.1	peptide cleavage/export ABC transporter	Regulator
ST4021_RS08005 (ST4021_08035)	-	1550754..1552499 (-)	1746	WP_011681577.1	ABC transporter ATP-binding protein	-
ST4021_RS08010 (ST4021_08040)	-	1552492..1554129 (-)	1638	WP_232991507.1	ABC transporter transmembrane domain-containing protein	-
ST4021_RS08015	-	1554438..1554644 (-)	207	WP_011681579.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80658.47 Da
• Isoelectric Point: 6.8843

>NTDB_id=510978 ST4021_RS08000 WP_041827772.1 1547587..1549740(-) (comA/nlmT) [Streptococcus thermophilus strain 4021]
MFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRELAKTNKEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDV
PYPFIAHVNKDGKLQHYYVIYKSTKDYLIIGDPDPSVKVTKMTKERFEKEWTGITLFMGPEPSYKPHKDKKNGLWDFLPL
IFKQRSLIANIVFASLLVTLINILGSYYLQGILDEYVPNQMKSTLGIISIGLVVTYVLQQMMTFARDYLLTILSQRFTID
VILSYIRHIFELPMSFFATRRTGEVISRFSDANSIIDALASTILSLFLDFSIVIIVGGVLLIQNSNLFKLVLCSVPIYTL
IVFAFMKPFERMNHDVMQSNAMVNSAIIEDINGIETIKSLTSEEVCYQKIDGEFIDYLDNSFRLSKLSILQTSLKQGAQL
ILNVLILWTGAQLVMGNTISIGQLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRLNEVYLIESEFGQSDDTYQEGIA
DGDITVTDLSYKYGFGRDTLTDVSLTIRQGEKISFVGVSGSGKTTLAKMLVNFYQPYKGHIDFNGQNISRIDKKTLRQHI
NYLPQQSYIFSGSVLENLTLGAARGITQADILKACEIAEIRQDIENMPMGFQTELSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKQVIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDHGRVVETGSHQDLMSYPGFYYQLFRK

Nucleotide

• Length: 2154 bp

>NTDB_id=510978 ST4021_RS08000 WP_041827772.1 1547587..1549740(-) (comA/nlmT) [Streptococcus thermophilus strain 4021]
ATGTTTCGTTTTCGTAGGACTTTTGTCCCTCAAATAGACATGAGGGATTGTGGAGTTGCTGCCTTGGCATCAGTGGCCAA
GTACTATGGTTCAGATTATTCATTAGCACATCTGCGTGAGTTGGCGAAGACCAATAAAGAAGGGACAACTGCCTTAGGTC
TTGTAGAGGCTGCTAAAAAAATTGGCTTTGAAACGAGAGCTATAAAGGCTGAAATGTCGCTCTTTGAGATGGAAGATGTT
CCTTATCCTTTTATTGCTCATGTTAATAAAGATGGGAAGCTTCAACATTATTATGTTATTTATAAAAGCACCAAGGATTA
TCTGATAATTGGAGACCCTGATCCAAGTGTAAAAGTAACTAAAATGACTAAAGAGCGTTTTGAGAAAGAGTGGACAGGTA
TTACTCTTTTTATGGGACCGGAACCCAGTTATAAACCACATAAGGATAAGAAAAATGGACTCTGGGACTTTCTCCCTTTG
ATCTTTAAACAAAGGTCCTTGATAGCTAATATTGTCTTTGCCAGTCTCTTGGTTACTTTAATAAATATTTTAGGTTCCTA
TTATTTACAAGGTATTCTAGACGAATATGTCCCTAATCAAATGAAGTCTACCTTAGGAATTATCTCAATTGGATTAGTTG
TGACCTATGTTTTACAACAAATGATGACTTTTGCAAGAGATTATCTCTTAACCATACTGAGTCAGCGATTTACCATTGAC
GTTATCTTGTCCTACATACGACATATCTTTGAACTCCCAATGTCTTTTTTTGCCACAAGACGTACAGGGGAGGTTATCTC
ACGTTTTAGTGATGCTAACTCTATTATCGATGCTCTGGCTTCGACGATATTATCACTTTTCCTTGATTTCTCTATTGTGA
TTATCGTAGGAGGCGTGTTATTGATACAAAATAGCAATCTCTTCAAGCTAGTTCTTTGTTCGGTTCCAATTTATACCCTT
ATCGTCTTTGCCTTTATGAAACCTTTTGAGCGAATGAATCATGACGTCATGCAGAGTAATGCTATGGTTAATTCAGCCAT
CATTGAGGACATTAATGGGATTGAAACCATAAAGTCACTAACCAGCGAAGAAGTATGCTATCAAAAGATTGATGGTGAGT
TTATTGACTATCTAGACAATTCTTTTCGCCTTTCTAAGTTATCTATACTACAAACATCATTGAAACAAGGTGCTCAACTT
ATTTTAAATGTACTTATCCTCTGGACAGGTGCTCAGTTGGTGATGGGAAATACCATTTCGATAGGACAATTGATTACTTT
TAATATGTTGCTTTCTTACTTCACGAATCCTTTGGAAAATATCATTAACCTGCAAACCAAGTTACAGTCTGCTAAGGTAG
CTAATACTAGGCTCAATGAGGTCTATCTGATTGAATCAGAGTTTGGACAAAGTGATGATACCTATCAAGAAGGCATTGCG
GATGGAGATATCACTGTTACGGATTTATCTTATAAATATGGTTTTGGTCGTGATACTTTGACTGATGTCAGTTTGACGAT
TAGACAAGGAGAAAAAATCAGTTTTGTTGGTGTCAGTGGATCTGGTAAGACTACTCTAGCTAAAATGTTGGTCAATTTTT
ATCAACCATATAAGGGGCACATAGATTTTAATGGTCAAAATATTAGTCGCATAGACAAGAAAACTCTTCGTCAACATATT
AACTATCTCCCTCAGCAATCCTATATATTTAGTGGTAGTGTTTTAGAAAATCTTACTTTAGGTGCAGCACGGGGTATTAC
GCAAGCTGATATTTTGAAAGCTTGTGAAATAGCAGAAATTCGTCAAGATATTGAAAACATGCCTATGGGGTTTCAGACAG
AGCTGTCTGATGGAGCAGGTCTGTCTGGAGGGCAAAAGCAACGTATCGCTTTGGCGCGTGCACTACTAACGAAATCTCCT
GTACTAATCTTAGATGAAGCAACTAGCGGATTGGATGTTTTGACAGAAAAGCAGGTTATTGATAACCTCCTAGCACTAAA
AGATAAAACGATCATCTTTGTAGCACACAGGCTTAGTATCGCTGAGCGGACCGACCGTATCGTAGTCATTGATCACGGAC
GCGTAGTGGAGACAGGTTCTCATCAAGACCTAATGTCTTATCCAGGTTTCTATTATCAATTATTTAGAAAGTGA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	67.787	99.582	0.675
comA	Streptococcus mitis NCTC 12261	65.963	99.163	0.654
comA	Streptococcus pneumoniae Rx1	65.541	99.163	0.65
comA	Streptococcus pneumoniae D39	65.541	99.163	0.65
comA	Streptococcus pneumoniae R6	65.541	99.163	0.65
comA	Streptococcus mitis SK321	65.26	99.163	0.647
comA	Streptococcus pneumoniae TIGR4	65.12	99.163	0.646
comA	Streptococcus gordonii str. Challis substr. CH1	64.146	99.582	0.639