Detailed information NTG0510866

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: STCNRZ887_RS08445
• Genome accession: NZ_CP065491
• Coordinates: 1639393..1640493 (-)
• Length: 366 a.a.
• NCBI ID: WP_148148900.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CNRZ887
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1634393..1645493

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ887_RS08405 (STCNRZ887_08405)	-	1635005..1635202 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
STCNRZ887_RS08410 (STCNRZ887_08410)	-	1635451..1636644 (-)	1194	WP_022096898.1	acetate kinase	-
STCNRZ887_RS08415 (STCNRZ887_08415)	comYH	1636700..1637656 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
STCNRZ887_RS08420 (STCNRZ887_08420)	comGG	1637701..1638018 (-)	318	WP_011226623.1	competence type IV pilus minor pilin ComGG	-
STCNRZ887_RS08425 (STCNRZ887_08425)	comYF	1637996..1638433 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
STCNRZ887_RS08430 (STCNRZ887_08430)	comGE	1638417..1638710 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
STCNRZ887_RS08435 (STCNRZ887_08435)	comYD	1638682..1639110 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
STCNRZ887_RS08440 (STCNRZ887_08440)	comYC	1639070..1639396 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
STCNRZ887_RS08445 (STCNRZ887_08445)	comYB	1639393..1640493 (-)	1101	WP_148148900.1	competence type IV pilus assembly protein ComGB	Machinery gene
STCNRZ887_RS08450 (STCNRZ887_08450)	comGA/cglA/cilD	1640375..1641316 (-)	942	WP_011226629.1	competence type IV pilus ATPase ComGA	Machinery gene
STCNRZ887_RS08455 (STCNRZ887_08455)	-	1641397..1641759 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41754.88 Da
• Isoelectric Point: 10.0449

>NTDB_id=510866 STCNRZ887_RS08445 WP_148148900.1 1639393..1640493(-) (comYB) [Streptococcus thermophilus strain CNRZ887]
MPEKISKTIRLPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=510866 STCNRZ887_RS08445 WP_148148900.1 1639393..1640493(-) (comYB) [Streptococcus thermophilus strain CNRZ887]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCTACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCAGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGATATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.394	90.164	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413