Detailed information NTG0510784

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: STCNRZ1575_RS05560
• Genome accession: NZ_CP065490
• Coordinates: 1042891..1043598 (-)
• Length: 235 a.a.
• NCBI ID: WP_095559389.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CNRZ1575
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1037891..1048598

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ1575_RS05535 (STCNRZ1575_05530)	yidA	1038242..1039051 (+)	810	WP_011226081.1	sugar-phosphatase	-
STCNRZ1575_RS05540 (STCNRZ1575_05535)	-	1039053..1040267 (+)	1215	WP_002953123.1	aminoacyltransferase	-
STCNRZ1575_RS05545 (STCNRZ1575_05540)	-	1040319..1040680 (-)	362	Protein_1023	YbaN family protein	-
STCNRZ1575_RS05550 (STCNRZ1575_05545)	vicX	1040740..1041552 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
STCNRZ1575_RS05555 (STCNRZ1575_05550)	vicK	1041558..1042898 (-)	1341	WP_084830671.1	cell wall metabolism sensor histidine kinase VicK	Regulator
STCNRZ1575_RS05560 (STCNRZ1575_05555)	vicR	1042891..1043598 (-)	708	WP_095559389.1	response regulator YycF	Regulator
STCNRZ1575_RS05565 (STCNRZ1575_05560)	-	1044120..1044887 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
STCNRZ1575_RS05570 (STCNRZ1575_05565)	-	1044899..1045732 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
STCNRZ1575_RS05575 (STCNRZ1575_05570)	-	1045750..1046448 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
STCNRZ1575_RS05580 (STCNRZ1575_05575)	-	1046460..1047110 (+)	651	WP_095559390.1	amino acid ABC transporter permease	-
STCNRZ1575_RS05585 (STCNRZ1575_05580)	endA	1047182..1048063 (-)	882	WP_022096754.1	DNA/RNA non-specific endonuclease	Machinery gene
STCNRZ1575_RS05590 (STCNRZ1575_05585)	-	1048125..1048313 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=510784 STCNRZ1575_RS05560 WP_095559389.1 1042891..1043598(-) (vicR) [Streptococcus thermophilus strain CNRZ1575]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREGLEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=510784 STCNRZ1575_RS05560 WP_095559389.1 1042891..1043598(-) (vicR) [Streptococcus thermophilus strain CNRZ1575]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGGTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTTGCCAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

• Response regulator receiver domain (Response_reg) (4-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.106	100	0.851
micA	Streptococcus pneumoniae Cp1015	79.828	99.149	0.791
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.726	99.574	0.455
scnR	Streptococcus mutans UA159	38.136	100	0.383