Detailed information NTG0510700

Bioinformatically predicted

Overview

• Name: mecA
• Type: Regulator
• Locus tag: STCNRZ302_RS01055
• Genome accession: NZ_CP065489
• Coordinates: 180904..181653 (+)
• Length: 249 a.a.
• NCBI ID: WP_179970775.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CNRZ302
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 175904..186653

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ302_RS01025 (STCNRZ302_01010)	-	176479..176649 (+)	171	WP_011680664.1	hypothetical protein	-
STCNRZ302_RS01030 (STCNRZ302_01015)	-	176736..176843 (+)	108	WP_011226802.1	LPXTG cell wall anchor domain-containing protein	-
STCNRZ302_RS01035 (STCNRZ302_01020)	-	176930..177670 (-)	741	WP_002949253.1	amino acid ABC transporter ATP-binding protein	-
STCNRZ302_RS01040 (STCNRZ302_01025)	-	177670..179220 (-)	1551	WP_014607891.1	ABC transporter substrate-binding protein/permease	-
STCNRZ302_RS01045 (STCNRZ302_01030)	-	179423..180277 (+)	855	WP_041828107.1	undecaprenyl-diphosphate phosphatase	-
STCNRZ302_RS01050 (STCNRZ302_01035)	-	180423..180638 (-)	216	WP_011226805.1	DUF3021 family protein	-
STCNRZ302_RS01055 (STCNRZ302_01040)	mecA	180904..181653 (+)	750	WP_179970775.1	adaptor protein MecA	Regulator
STCNRZ302_RS01060 (STCNRZ302_01045)	-	181657..182814 (+)	1158	WP_167401408.1	MraY family glycosyltransferase	-
STCNRZ302_RS01065 (STCNRZ302_01050)	sufC	182974..183744 (+)	771	WP_002947634.1	Fe-S cluster assembly ATPase SufC	-
STCNRZ302_RS01070 (STCNRZ302_01055)	sufD	183781..185043 (+)	1263	WP_002947640.1	Fe-S cluster assembly protein SufD	-
STCNRZ302_RS01075 (STCNRZ302_01060)	-	185097..186329 (+)	1233	WP_011225367.1	cysteine desulfurase	-

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29147.66 Da
• Isoelectric Point: 4.0659

>NTDB_id=510700 STCNRZ302_RS01055 WP_179970775.1 180904..181653(+) (mecA) [Streptococcus thermophilus strain CNRZ302]
MEMKQINETTLKIMITMEDLEEHGMELKDFLISQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEALDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSEFYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide

• Length: 750 bp

>NTDB_id=510700 STCNRZ302_RS01055 WP_179970775.1 180904..181653(+) (mecA) [Streptococcus thermophilus strain CNRZ302]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTTCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGCCCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGAGCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAATTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

• Negative regulator of genetic competence (MecA) (MecA) (1-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mecA	Streptococcus thermophilus LMG 18311	99.598	100	0.996
mecA	Streptococcus thermophilus LMD-9	98.795	100	0.988
mecA	Streptococcus mutans UA159	56.967	97.992	0.558
mecA	Streptococcus pneumoniae Rx1	45.783	100	0.458
mecA	Streptococcus pneumoniae D39	45.783	100	0.458
mecA	Streptococcus pneumoniae R6	45.783	100	0.458
mecA	Streptococcus pneumoniae TIGR4	45.783	100	0.458