Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   STAVA1121_RS06800 Genome accession   NZ_CP065488
Coordinates   1276199..1278070 (-) Length   623 a.a.
NCBI ID   WP_347131145.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain AVA1121     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1271199..1283070
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STAVA1121_RS06765 (STAVA1121_06680) rimM 1271606..1272124 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  STAVA1121_RS06780 (STAVA1121_06695) - 1272800..1273444 (-) 645 WP_002951384.1 response regulator transcription factor -
  STAVA1121_RS06785 (STAVA1121_06700) - 1273434..1274444 (-) 1011 WP_164178207.1 sensor histidine kinase -
  STAVA1121_RS06790 (STAVA1121_06705) liaF 1274441..1275139 (-) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  STAVA1121_RS06795 - 1275410..1275562 (-) 153 WP_347131144.1 ion channel -
  STAVA1121_RS06800 (STAVA1121_06715) stkP/pknB 1276199..1278070 (-) 1872 WP_347131145.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  STAVA1121_RS06805 (STAVA1121_06720) - 1278070..1278807 (-) 738 WP_002946881.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  STAVA1121_RS06810 (STAVA1121_06725) rsmB 1278851..1280173 (-) 1323 WP_014608533.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  STAVA1121_RS06815 (STAVA1121_06730) fmt 1280163..1281098 (-) 936 WP_002951411.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 67775.62 Da        Isoelectric Point: 6.9480

>NTDB_id=510671 STAVA1121_RS06800 WP_347131145.1 1276199..1278070(-) (stkP/pknB) [Streptococcus thermophilus strain AVA1121]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNESVAIKVLRTNYQTDQVAVARFQREARAMTELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKFIQDHAPLSNQDAVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGRAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPFDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHSRDSKVVFDDMTDAKTLPKVDSVPSVGPEKKISPKPSEPTPAP
SKQPREKASLSKKKKNLFSTLLKVLLGFVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKLESAGFKVGDVKEVEND
SVNKGKVIKTDPAAGTMRKEGASIDVYVSSGSKGFTLKNYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDNAKEGEILS
QSSEKNKSLNPKDSKAKIKFRVATPKTITMPDVTGLTVSTAVQTLNSKDISSSSIEYHDYNTGVKLDKSKVPSNTEVLYQ
DPQVGTAVDGTVILYVSVVTKSSSIQQSSSASTTQSPSSTSSSSESSTASSTETATEATHTEQ

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=510671 STAVA1121_RS06800 WP_347131145.1 1276199..1278070(-) (stkP/pknB) [Streptococcus thermophilus strain AVA1121]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGTGTAGCTATTAAGGTGCTACGTACCAATTATCAAACTGATCAGGTTG
CTGTGGCGCGTTTCCAGCGTGAAGCACGTGCCATGACTGAGCTTAGCCATCCGAATATCGTTGCGATTAGAGATATTGGT
GAAGAAGACGGTCAGCAGTTCTTGGTGATGGAGTATGTGGATGGTTCGGACTTGAAGAAATTCATTCAAGACCATGCACC
ATTGTCTAACCAAGATGCTGTGCGTATTATGGGGGAAGTCCTTTCCGCCATGACTCTTGCCCACCAAAAGGGTATTATTC
ACCGTGACCTTAAGCCACAGAACGTTCTATTAACTAAGGATGGTAGAGCTAAGGTTACAGACTTTGGTATCGCAGTAGCA
TTTGCTGAAACCAGCCTGACACAAACTAACTCAATGTTGGGGTCAGTCCATTATTTGTCACCAGAACAGGCACGTGGTTC
TAAAGCCACTATCCAAAGTGATATCTATGCTATGGGGATTATGCTCTTTGAAATGTTGACAGGGCATATCCCTTTTGATG
GCGATAGTGCAGTAACCATTGCACTTCAACATTTCCAAAAGCCCCTGCCATCGATTTTGGCTGAGAACCGTAACGTTCCT
CAAGCTTTAGAAAATGTTGTTATTAGAGCAACTGCTAAAAAGCTTGAAAATCGTTACAACAGCACTTTGGAAATGAGTCG
CGACCTAGTAACTAGTTTGCATCCTAGTCATAGTCGTGATTCTAAGGTAGTTTTTGATGACATGACGGATGCTAAGACCC
TGCCAAAGGTTGATTCAGTTCCATCAGTAGGTCCTGAGAAAAAGATTTCTCCTAAACCATCAGAGCCTACACCGGCTCCA
AGCAAACAACCGAGGGAAAAAGCTTCTCTATCTAAAAAAAAGAAAAATCTCTTTTCAACTCTACTCAAGGTTTTACTAGG
CTTCGTCTTTATAGGAATTATCATTTTTGCCTATCTTGTTTTTACCAATCCTGACAATGTCCAAGTACCAAATGTTGTAG
GTCAAGAGTTGTCAACAGCTCAGACGAAACTTGAAAGTGCAGGCTTTAAGGTTGGCGATGTTAAAGAAGTCGAAAATGAT
TCAGTCAATAAGGGCAAAGTTATCAAGACCGACCCTGCAGCTGGGACAATGCGTAAAGAAGGAGCAAGCATTGATGTCTA
TGTTTCTTCTGGTAGCAAAGGTTTCACTCTGAAAAATTACAAGGGGAAAAATTATAAGGATGCCATTGAGGATTTAACCT
CGAATTATGGGGTTTCCGAGGATCAGATCGATATTCAACATGTCGAAGACGATAATGCTAAAGAAGGCGAAATTCTATCT
CAAAGTTCGGAGAAAAACAAGTCCCTCAATCCTAAAGATAGTAAGGCAAAAATCAAGTTTCGTGTGGCAACTCCTAAGAC
TATAACTATGCCTGATGTGACTGGTTTAACTGTCTCGACAGCAGTCCAAACCTTGAATAGTAAAGACATTTCAAGTAGCA
GTATTGAGTATCATGACTATAATACTGGTGTTAAGTTGGATAAGAGTAAGGTACCTAGTAATACAGAGGTCCTTTATCAA
GATCCTCAAGTTGGTACTGCTGTTGATGGCACAGTGATTCTCTATGTTTCAGTCGTAACTAAGAGTTCAAGTATTCAACA
GTCAAGCTCAGCAAGTACGACACAATCGCCGTCATCTACAAGTTCTAGTTCTGAAAGTAGTACAGCTTCTAGTACCGAAA
CAGCTACAGAAGCTACTCACACAGAGCAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(508-577)

PASTA domain (PASTA)

(367-429)

PASTA domain (PASTA)

(436-502)

Protein kinase domain (Pkinase)

(12-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

90.189

93.258

0.841
  pknB Streptococcus mutans UA159

64.338

87.319

0.562
  stkP Streptococcus pneumoniae TIGR4

58.248

78.812

0.459
  stkP Streptococcus pneumoniae D39

58.045

78.812

0.457
  stkP Streptococcus pneumoniae R6

58.045

78.812

0.457
  stkP Streptococcus pneumoniae Rx1

57.841

78.812

0.456